Protein Alignment CG7806 and Abcc4

DIOPT Version :10

• Sequence 1: NP_609207.1
• Gene: CG7806 / 34140
• FlyBaseID: FBgn0032018
• Length: 1487
• Species: Drosophila melanogaster
• Sequence 2: XP_038948894.1
• Gene: Abcc4 / 170924
• RGDID: 620266
• Length: 1382
• Species: Rattus norvegicus
• Alignment Length: 1387
• Identity: 434/1387 - (31%)
• Similarity: 691/1387 - (49%)
• Gaps: 197/1387 - (14%)

  Fly   229 EANLGSRFLFHWVQPLILKGVAGKLRKIE--DLFDLPDALNITRLSEKLH----------LALSQ 281
            :|||.||..|.|:.||.   .||..|::|  |:|.:........|.|:|.          ...::
  Rat    15 DANLCSRLFFWWLNPLF---KAGHKRRLEEDDMFSVLPEDRSKHLGEELQGYWDKEVLRAKKDAR 76

  Fly   282 SQSLWRALHRCFGVEFYLIGILRLIADLSGFAGPLLLGGLL-------RQDHADPNQVYYYALGL 339
            ..||.:|:.:|:...:.::||..||.:.:....|:.||.::       ..|.|..:..|.||..|
  Rat    77 KPSLTKAIVKCYWKSYLILGIFTLIEETTRVVQPIFLGKIIDYFEKYDSDDSAALHTAYGYAAVL 141

  Fly   340 FGSTLLSAVCATHFDWRMAMVSMKMRVGVVNSIYRKAL----EARGLKESKPDLLNLMSTDTDRI 400
            ...||:.|:....:.:.:....|::||.:.:.||||||    .|.| |.:...::||:|.|.::.
  Rat   142 SLCTLILAILHHLYFYHVQCAGMRIRVAMCHMIYRKALRLSNSAMG-KTTTGQIVNLLSNDVNKF 205

  Fly   401 VNSCISFHFFWSIPFKLFTTLYLLYLQLGAAFLAGVIFAALLIPINRWLAKRIGIFSSGLMTAKD 465
            ....|..||.|:.|.:......||::::|.:.|||:....:|:|:...:.|......|......|
  Rat   206 DQVTIFLHFLWAGPLQAIGVTILLWVEIGISCLAGLAILVILLPLQSCIGKLFSSLRSKTAAFTD 270

  Fly   466 ARLSATTETMQGAKQIKINAWEDIFITKIRGLRQEELRFLSKRKYLDA--MCVYFWATTPVLMCL 528
            ||:....|.:.|.:.||:.|||..|...|..||::|:..:....||..  |..:|.|...:|  .
  Rat   271 ARIRTMNEVITGMRIIKMYAWEKSFADLITNLRKKEISKILGSSYLRGMNMASFFIANKVIL--F 333

  Fly   529 LTFGVSVLMGNPLIAS------TTYTSVALLYMLIGPLNAFPWVLNGLIEAWVSIKRVQQLMDVP 587
            :||...||:||.:.||      |.|.:|.|...|.     ||..:..:.||.||::|::..:.:.
  Rat   334 VTFTTYVLLGNKITASHVFVAMTLYGAVRLTVTLF-----FPSAIERVSEAVVSVRRIKNFLLLD 393

  Fly   588 NLDYSSYYNPIMRGSGGSGAGDDAPLDAPKASVLQMKCASFCHDSDEQTSPTPFRMKDINVDIKA 652
            .|.......|    |.|            ||.|......:|.    ::...|| .::.::...:.
  Rat   394 ELPERKAQEP----SDG------------KAIVHVQDFTAFW----DKALDTP-TLQGLSFTARP 437

  Fly   653 GQLVCIEGPVGGGKSSFLSAIVANLQCTDGEVCVQELTTGFGYVPQSPWLQRGTIRDNIVWGAQF 717
            |:|:.:.||||.||||.|||::..|..|.|.|.|.   ....||.|.||:..||:|.||::|.::
  Rat   438 GELLAVVGPVGAGKSSLLSAVLGELPPTSGLVSVH---GRIAYVSQQPWVFSGTVRSNILFGRKY 499

  Fly   718 DEQWYKTVLHACALEEDLQIL-GGDLVGVGENGRTLSGGQRARVALARAVYQDKKVYLLDDVLSS 781
            :::.|:.|:.||||::|||:| .|||..:|:.|.||||||:|||.||||||||..:|||||.||:
  Rat   500 EKERYEKVIKACALKKDLQLLEDGDLTVIGDRGATLSGGQKARVNLARAVYQDADIYLLDDPLSA 564

  Fly   782 LDAHVARHIIKHCILRLLKHKTRIVVTRNIQLFFHANQILQVKDGQLLP----SEYMTQSIEL-S 841
            :||.|.:|:.:.||.:.|..|..|:||..:|....|:.||.:|||:::.    :|::...::. |
  Rat   565 VDAEVGKHLFQLCICQTLHEKITILVTHQLQYLKAASHILILKDGEMVQKGTYTEFLKSGVDFGS 629

  Fly   842 LDEDADDEQE-------PTVRRRSVE-----------------LSNQYDKKSLDSLLLEELREYG 882
            |.:..::|.|       ||:|.|:..                 :.:..|.::..:...||.|..|
  Rat   630 LLKKENEEAEPSPVPGTPTLRNRTFSEASIWSQQSSRPSLKDGVPDAQDAENTQAAQPEESRSEG 694

  Fly   883 HLSGNVFTCYWKAVTS--PLAFTVLLSVVLMQLTRNLSDAWLAYWVT-ETTLDPHKNDTSLDHIL 944
            .:....:..|:.|..|  .:.|.|||: ::.|:...|.|.||::|.. :..|:..||..
  Rat   695 RIGFKAYKNYFSAGASWFFIIFLVLLN-LMGQVFYVLQDWWLSHWANRQGALNDTKNAN------ 752

  Fly   945 MRPTVGNETESGHTTKFYLSIFTAIAVSNSLVTLARAFLFAYAGIKAAIFMHEKLLKKVMFAKFN 1009
                 ||.|.: ....:||.|:|.:.....|..:||:.|..|..:.|:..:|.::.:.::.|...
  Rat   753 -----GNVTGT-LDLSWYLGIYTGLTAVTVLFGIARSLLVFYVLVNASQTLHNRMFESILKAPVL 811

  Fly  1010 FFD----------------------------------------ITSV-----------------G 1017
            |||                                        :|||                 |
  Rat   812 FFDRNPIELTQLEVFRVVDGALDSHRHLSHPHPWPQNGSLQASVTSVTGSDVIRFPEVLLLALPG 876

  Fly  1018 RILNRFSSDTNTVDDSLP-----FILNILLAQLAGLVGALCVSLYAMPWLGLVIIPMVPIYLSLQ 1077
            |||||||.|...:||.||     ||..:||     :|..:.|:...:||:.:.::|:..|::.|:
  Rat   877 RILNRFSKDIGHMDDLLPLTFLDFIQTLLL-----VVSVIAVAAAVIPWILIPLVPLSIIFVVLR 936

  Fly  1078 QRYRHASRDIKRLSSNAMSPLYTHFTETLQGLTTIRSMRASPRFQRDFQVKLEESIKAQLTQSAA 1142
            :.:...|||:|||.|...||:::|.:.:||||.|||:.:|..|.|..|....:...:|.......
  Rat   937 RYFLETSRDVKRLESTTRSPVFSHLSSSLQGLWTIRAYKAEERCQELFDAHQDLHSEAWFLFLTT 1001

  Fly  1143 QQWLALRLQLLGTLLVGGAGLLAA---ITASHTTNPGLVGLCISYALSITGQLGDLLHAVAETEQ 1204
            .:|.|:||..:..:.|    ::.|   :..:.|.:.|.|||.:||:|::.|.....:...||.|.
  Rat  1002 SRWFAVRLDAICAVFV----IVVAFGSLVLAKTLDAGQVGLALSYSLTLMGMFQWSVRQSAEVEN 1062

  Fly  1205 ELVAVERIDQYLQLEEEQNASGSAEPPFGWPTQGVLSFREVQLSYREHLAPALRGITFQTEAFER 1269
            .:::|||:.:|..||:|........||.|||.:||:.|..|..:|.......|:.:|...::.|:
  Rat  1063 MMISVERVIEYTDLEKEAPWECRKRPPPGWPHEGVIVFDNVNFTYSLDGPLVLKHLTALIKSREK 1127

  Fly  1270 IGIVGRTGAGKTSVLAALLRVAPLTHGEIRLDQVNLKTLPLSVLRERIGVITQEPFLFEGTVREN 1334
            :||||||||||:|:::||.|::. ..|:|.:|::....:.|..||:::.:|.|||.||.||:|:|
  Rat  1128 VGIVGRTGAGKSSLISALFRLSE-PEGKIWIDKILTTEIGLHDLRKKMSIIPQEPVLFTGTMRKN 1191

  Fly  1335 LDPRHGFYDSEIWHAIKNSAAATLLVQQLGGLDGKVET----CGNNLSAGQRQLLCLARALLKNA 1395
            |||.:...|.|:|.|::.    ..|.:.:..|.||::|    .|:|.|.|||||:|||||:||..
  Rat  1192 LDPFNEHSDEELWKALEE----VQLKEAIEDLPGKMDTELAESGSNFSVGQRQLVCLARAILKKN 1252

  Fly  1396 KVVAIDEGTSNLDDESDLSIQQALRNAFKSCTLLFIAHRLRGLHAMDRIIVLDDGRICEEGNPQS 1460
            :::.|||.|:|:|..:|..|||.:|..|..||:|.|||||..:...|:|:|||.||:.|...|..
  Rat  1253 RILIIDEATANVDPRTDELIQQKIREKFAQCTVLTIAHRLNTIIDSDKIMVLDSGRLREYDEPYV 1317

  Fly  1461 LASDSSTIFYGMLLAQDIDPGE 1482
            |..:..::||.|:  |.:..||
  Rat  1318 LLQNPESLFYKMV--QQLGKGE 1337

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7806	NP_609207.1	MRP_assoc_pro	6..1472	CDD:188098	430/1375 (31%)
Abcc4	XP_038948894.1	MRP_assoc_pro	6..1334	CDD:188098	432/1382 (31%)