Protein Alignment CG7806 and ABCC5

DIOPT Version :10

• Sequence 1: NP_609207.1
• Gene: CG7806 / 34140
• FlyBaseID: FBgn0032018
• Length: 1487
• Species: Drosophila melanogaster
• Sequence 2: NP_005679.2
• Gene: ABCC5 / 10057
• HGNCID: 56
• Length: 1437
• Species: Homo sapiens
• Alignment Length: 1372
• Identity: 419/1372 - (30%)
• Similarity: 673/1372 - (49%)
• Gaps: 159/1372 - (11%)

  Fly   225 HAQDEANLGSRFLFHWVQPLI-LKGVAGKLRKIEDLFDL----PDALNITRL----SEKLHLALS 280
            |..|.|.|.|...|.|:..|. :....|:| .:||::.|    ...:|..||    .|:|:....
Human    99 HPVDNAGLFSCMTFSWLSSLARVAHKKGEL-SMEDVWSLSKHESSDVNCRRLERLWQEELNEVGP 162

  Fly   281 QSQSLWRALHRCFGVEFYLIGILRLIADLSGFAGP-LLLGGLLRQDHADPNQVYYYALGLFGSTL 344
            .:.||.|.:.........|..:..:|..|:||:|| .::..||....|..:.:.|..|.:.|..|
Human   163 DAASLRRVVWIFCRTRLILSIVCLMITQLAGFSGPAFMVKHLLEYTQATESNLQYSLLLVLGLLL 227

  Fly   345 LSAVCATHFDWRMAM-------VSMKMRVGVVNSIYRKALEARGLKE-SKPDLLNLMSTDTDRIV 401
            ...|.:    |.:|:       ..:::|..::...::|.|:.:.:|| |..:|:|:.|.|..|:.
Human   228 TEIVRS----WSLALTWALNYRTGVRLRGAILTMAFKKILKLKNIKEKSLGELINICSNDGQRMF 288

  Fly   402 NSCISFHFFWSIPFKLFTTLYLLY--LQLG-AAFLAGVIFAALLIPINRWLAKRIGIFSSGLMTA 463
            .:..........|  :...|.::|  :.|| ..||...:| .|..|...:.::....|....:.|
Human   289 EAAAVGSLLAGGP--VVAILGMIYNVIILGPTGFLGSAVF-ILFYPAMMFASRLTAYFRRKCVAA 350

  Fly   464 KDARLSATTETMQGAKQIKINAWEDIFITKIRGLRQEELRFLSKRKYLDAMCVYFWATTPVLMCL 528
            .|.|:....|.:...|.||:.||...|...::.:|:||.|.|.|..|..::.|.......|:..:
Human   351 TDERVQKMNEVLTYIKFIKMYAWVKAFSQSVQKIREEERRILEKAGYFQSITVGVAPIVVVIASV 415

  Fly   529 LTFGVSVLMGNPLIASTTYTSVALLYMLIGPLNAFPWVLNGLIEAWVSIKRVQQ--LMD----VP 587
            :||.|.:.:|..|.|:..:|.|.:...:...|...|:.:..|.||.|::.|.:.  ||:    :.
Human   416 VTFSVHMTLGFDLTAAQAFTVVTVFNSMTFALKVTPFSVKSLSEASVAVDRFKSLFLMEEVHMIK 480

  Fly   588 NLDYSSYY-----NPIMRGSGGSGAGDDAPLDAPK-----------------------ASVLQMK 624
            |...|.:.     |..:.......:..::|...||                       .:||..:
Human   481 NKPASPHIKIEMKNATLAWDSSHSSIQNSPKLTPKMKKDKRASRGKKEKVRQLQRTEHQAVLAEQ 545

  Fly   625 CASFCHDSDEQTSPTPFRMK--------------DINVDIKAGQLVCIEGPVGGGKSSFLSAIVA 675
            ......||||:.||.....|              .|:::|:.|:||.|.|.||.||:|.:|||:.
Human   546 KGHLLLDSDERPSPEEEEGKHIHLGHLRLQRTLHSIDLEIQEGKLVGICGSVGSGKTSLISAILG 610

  Fly   676 NLQCTDGEVCVQELTTGFGYVPQSPWLQRGTIRDNIVWGAQFDEQWYKTVLHACALEEDLQIL-G 739
            .:...:|.:.:   :..|.||.|..|:...|:||||::|.::||:.|.:||::|.|..||.|| .
Human   611 QMTLLEGSIAI---SGTFAYVAQQAWILNATLRDNILFGKEYDEERYNSVLNSCCLRPDLAILPS 672

  Fly   740 GDLVGVGENGRTLSGGQRARVALARAVYQDKKVYLLDDVLSSLDAHVARHIIKHCILRLLKHKTR 804
            .||..:||.|..||||||.|::||||:|.|:.:|:|||.||:|||||..||....|.:.||.||.
Human   673 SDLTEIGERGANLSGGQRQRISLARALYSDRSIYILDDPLSALDAHVGNHIFNSAIRKHLKSKTV 737

  Fly   805 IVVTRNIQLFFHANQILQVKDGQL-----------LPSEYMTQSIELSLDEDADDEQEPTVRRRS 858
            :.||..:|.....::::.:|:|.:           |..:|.|....|.|.|      .|.|...|
Human   738 LFVTHQLQYLVDCDEVIFMKEGCITERGTHEELMNLNGDYATIFNNLLLGE------TPPVEINS 796

  Fly   859 VELSNQYDKKSLDS--------------------LLLEELREYGHLSGNVFTCYWKAVTSPLAFT 903
            .:.::...|||.|.                    :.||| :..|.:..:|:..|.:|...||||.
Human   797 KKETSGSQKKSQDKGPKTGSVKKEKAVKPEEGQLVQLEE-KGQGSVPWSVYGVYIQAAGGPLAFL 860

  Fly   904 VLLSVVLMQL-TRNLSDAWLAYWVTETTLDPHKNDTSLDHILMRPTVGNETESGHTTK------F 961
            |::::.::.: :...|..||:||:.:.:     .:|::       |.||||....:.|      :
Human   861 VIMALFMLNVGSTAFSTWWLSYWIKQGS-----GNTTV-------TRGNETSVSDSMKDNPHMQY 913

  Fly   962 YLSIFTAIAVSNSLVTLA-RAFLFAYAGIKAAIFMHEKLLKKVMFAKFNFFDITSVGRILNRFSS 1025
            |.||: |::::..|:..| |..:|....::|:..:|::|.::::.:...|||.|..||||||||.
Human   914 YASIY-ALSMAVMLILKAIRGVVFVKGTLRASSRLHDELFRRILRSPMKFFDTTPTGRILNRFSK 977

  Fly  1026 DTNTVDDSLP-----FILNILLAQLAGLVGALCVSLYA--MPWLGLVIIPMVPIYLSLQQRYRHA 1083
            |.:.||..||     ||.|::|.       ..||.:.|  .||..:.:.|:|.::..|....|..
Human   978 DMDEVDVRLPFQAEMFIQNVILV-------FFCVGMIAGVFPWFLVAVGPLVILFSVLHIVSRVL 1035

  Fly  1084 SRDIKRLSSNAMSPLYTHFTETLQGLTTIRSMRASPRFQRDFQVKLEESIKAQLTQSAAQQWLAL 1148
            .|::|||.:...||..:|.|.::|||.||.:......|...:|..|:::.......:.|.:|||:
Human  1036 IRELKRLDNITQSPFLSHITSSIQGLATIHAYNKGQEFLHRYQELLDDNQAPFFLFTCAMRWLAV 1100

  Fly  1149 RLQLLGTLLVGGAGLLAAITASHTTNPGLVGLCISYALSITGQLGDLLHAVAETEQELVAVERID 1213
            ||.|:...|:...||:..:...... |...||.||||:.:||.....:...:|||....:||||:
Human  1101 RLDLISIALITTTGLMIVLMHGQIP-PAYAGLAISYAVQLTGLFQFTVRLASETEARFTSVERIN 1164

  Fly  1214 QY---LQLEEEQNASGSAEPPFGWPTQGVLSFREVQLSYREHLAPALRGITFQTEAFERIGIVGR 1275
            .|   |.||........|..| .||.:|.::|...::.|||:|...|:.::|..:..|:||||||
Human  1165 HYIKTLSLEAPARIKNKAPSP-DWPQEGEVTFENAEMRYRENLPLVLKKVSFTIKPKEKIGIVGR 1228

  Fly  1276 TGAGKTSVLAALLRVAPLTHGEIRLDQVNLKTLPLSVLRERIGVITQEPFLFEGTVRENLDPRHG 1340
            ||:||:|:..||.|:..|:.|.|::|.|.:..:.|:.||.::.:|.|||.||.||||.||||.:.
Human  1229 TGSGKSSLGMALFRLVELSGGCIKIDGVRISDIGLADLRSKLSIIPQEPVLFSGTVRSNLDPFNQ 1293

  Fly  1341 FYDSEIWHAIKNSAAATLLVQQLGGLDGKVETCGNNLSAGQRQLLCLARALLKNAKVVAIDEGTS 1405
            :.:.:||.|::.:.....:.|....|:.:|...|:|.|.|:|||||:|||||::.|::.:||.|:
Human  1294 YTEDQIWDALERTHMKECIAQLPLKLESEVMENGDNFSVGERQLLCIARALLRHCKILILDEATA 1358

  Fly  1406 NLDDESDLSIQQALRNAFKSCTLLFIAHRLRGLHAMDRIIVLDDGRICEEGNPQSLASDSSTIFY 1470
            .:|.|:||.||:.:|.||..||:|.|||||..:...|||:||..|::.|...|..|.|:.|:.||
Human  1359 AMDTETDLLIQETIREAFADCTMLTIAHRLHTVLGSDRIMVLAQGQVVEFDTPSVLLSNDSSRFY 1423

  Fly  1471 GMLLAQD 1477
            .|..|.:
Human  1424 AMFAAAE 1430

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7806	NP_609207.1	MRP_assoc_pro	6..1472	CDD:188098	417/1365 (31%)
ABCC5	NP_005679.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	15..41
		PLN03130	100..1425	CDD:215595	416/1364 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	501..538		3/36 (8%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	794..827		5/32 (16%)