DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7806 and tap1

DIOPT Version :9

Sequence 1:	NP_609207.1	Gene:	CG7806 / 34140	FlyBaseID:	FBgn0032018	Length:	1487	Species:	Drosophila melanogaster
Sequence 2:	XP_002665053.1	Gene:	tap1 / 100333043	ZFINID:	ZDB-GENE-050517-43	Length:	731	Species:	Danio rerio

Alignment Length:	652	Identity:	170/652 - (26%)
Similarity:	291/652 - (44%)	Gaps:	104/652 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   867 KKSLDSLLL----EELREYGHLSGNVFTCYWKAVTSPLA----FTVLLSVVLMQLTRNLSDAWLA 923
            |:.:.::||    |...:.|..|......|.|..:...|    |.|:.|:..|.:
Zfish   125 KRHVPTILLTAKKERTEKKGKASLQRLLGYMKPFSGRFAAVFFFVVISSLGEMAI---------- 179

  Fly   924 YWVTETTLDPHKNDTSLDHILMRPTVGNETES---GHTTKFYLSIFTAIAVSNSL---------- 975
                     ||......|.|:      ||.|.   .|.    :::.|.:.:.:::
Zfish   180 ---------PHYTGKMTDWIM------NEDEPEAFNHA----ITVMTLMTIMSAVCEFVCDLIYN 225

  Fly   976 VTLARAFLFAYAGIKAAIFMHEKLLKKVMFAKFNFFDITSVGRILNRFSSDTNTVDDSLPFILNI 1040
            :|::|    .:..|:..:|  :.:||:    ...|||..:.|.|::|.::||||:.:||...|::
Zfish   226 ITMSR----IHTSIQGLVF--QAVLKQ----DIAFFDKATTGDIVSRITTDTNTMSESLSEKLSL 280

  Fly  1041 LL------AQLAGLVGALCVSLYAMPWLGLVIIPMVP-IYLSLQQRYRHASRDIKRLSSNAMSPL 1098
            |:      ..|.|.:..|...|.....|||.:|.::| |:          .|..::||:.....|
Zfish   281 LMWYFMRVIFLFGSMLMLSTRLCCFTLLGLPVIWIIPEIF----------GRFYQKLSAQVQDSL 335

  Fly  1099 YTH---FTETLQGLTTIRSMRASPRFQRDFQVKLEESI---KAQLTQSAAQQW------LALRLQ 1151
            ...   .|||...:.|:||..........::..||::.   |.:....|...|      |||::.
Zfish   336 AKANEVATETFSSMKTVRSFANEDGETERYRKCLEDTFALNKVEAAAYAVSTWTNSMSSLALKVS 400

  Fly  1152 LLGTLLVGGAGLLAAITASHTTNPGLVGLCISYALSITGQLGDLLHAVAETEQELVAVERIDQYL 1216
            :   |..||    ..:|.|..::..||.. :.|.|..|..:..|:......::.:.|.|:|.:|:
Zfish   401 I---LYYGG----RLVTGSDVSSGDLVSF-VLYELQFTSAVEVLMSYWPHVKKAVGASEKIFEYV 457

  Fly  1217 QLEEEQNASGSAEPPFGWPTQGVLSFREVQLSY-REHLAPALRGITFQTEAFERIGIVGRTGAGK 1280
            ..:.:....||..|.   ..:|.:.||.|..:| :......|:.::.:.:|.:...:||.:|:||
Zfish   458 DRKPDVPPDGSLAPK---TLKGHVQFRNVTFAYPKRPDTDVLKNVSLELKAGKITALVGPSGSGK 519

  Fly  1281 TSVLAALLRVAPLTHGEIRLDQVNLKTLPLSVLRERIGVITQEPFLFEGTVRENLD-PRHGFYDS 1344
            |:|::.|.|.....:|||.|||..|.:.....|.|:|.|::|||.||..:||||:. .:....:.
Zfish   520 TTVVSLLERFYQPQNGEILLDQKPLLSYKDQYLHEKISVVSQEPVLFARSVRENIKYGKENATNE 584

  Fly  1345 EIWHAIKNSAAATLLVQQLGGLDGKVETCGNNLSAGQRQLLCLARALLKNAKVVAIDEGTSNLDD 1409
            ||:.|.:.:.|...:.....|.|......|..:|.||:|.:.:||||::..:::.:|:.||:||.
Zfish   585 EIYAAARLANAHDFISSLPKGYDTDAGEKGGQVSGGQKQRIAIARALIQKPQILVLDDATSSLDT 649

  Fly  1410 ESDLSIQQALRNAFKSCTLLFIAHRLRGLHAMDRIIVLDDGRICEEGNPQSLASDSSTIFYGMLL 1474
            ||:..:..||:...:|||:|.|:|||.|:...|.|:.|.:|.:.||||.|.|.....  ||...:
Zfish   650 ESEHRVYSALKKELQSCTVLLISHRLSGVENADHILFLREGELVEEGNHQQLLDKQG--FYAEFV 712

  Fly  1475 AQ 1476
            .|
Zfish   713 KQ 714

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7806	NP_609207.1	MRP_assoc_pro	6..1472	CDD:188098	169/646 (26%)
		ABC_membrane	328..560	CDD:294371
		ABCC_MRP_domain1	621..827	CDD:213217
		ABC_membrane	948..1192	CDD:279056	63/275 (23%)
		ABCC_MRP_domain2	1238..1458	CDD:213211	76/221 (34%)
tap1	XP_002665053.1	3a01208	42..712	CDD:273363	169/648 (26%)
		ABC_membrane	166..433	CDD:279056	71/323 (22%)
		P-loop_NTPase	467..692	CDD:304359	76/227 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000