Protein Alignment CG7806 and abcc5

DIOPT Version :9

• Sequence 1: NP_609207.1
• Gene: CG7806 / 34140
• FlyBaseID: FBgn0032018
• Length: 1487
• Species: Drosophila melanogaster
• Sequence 2: XP_012818083.1
• Gene: abcc5 / 100125060
• XenbaseID: XB-GENE-986260
• Length: 1437
• Species: Xenopus tropicalis
• Alignment Length: 1425
• Identity: 423/1425 - (29%)
• Similarity: 686/1425 - (48%)
• Gaps: 188/1425 - (13%)

  Fly   183 IPKGSAVYSSLPRSGVSAREDEGLLSQRY-----TYFQFDLNESHLGHAQDEANLGSRFLFHWVQ 242
            :|...:|:|:|...      |||....:|     ....|.:...| .|..|.|.|.|...|.|:.
 Frog    60 LPLDISVHSNLKIL------DEGHHKGKYHKGLNLLKPFRITSKH-QHPVDNAGLFSFMTFSWLT 117

  Fly   243 PLILKGVAGKLRKI--EDLFDL----PDALNITRLSEKLHL----ALSQSQSLWRALHRCFGVEF 297
            |  :..:|.|..::  ||::.|    ...:|..|| |||.|    .....:|..|::...|....
 Frog   118 P--MARIAYKKGELFFEDIWPLSKHESSDINSKRL-EKLWLEEVTEKGADESSLRSVVWHFCRTR 179

  Fly   298 YLIGILRL-IADLSGFAGP-LLLGGLL---RQDHADPNQVYYYALGLFGSTLLSAVCATHFDWRM 357
            .:|.|:.| :..|:||.|| .::..||   :|...||.    |:|.|..:.|::.:..:   |.:
 Frog   180 LIISIMCLMLTQLAGFIGPAFVVKSLLEYTQQSSKDPG----YSLLLVFALLMTEIVRS---WSL 237

  Fly   358 AM-------VSMKMRVGVVNSIYRKALEARGLKE-SKPDLLNLMSTDTDRIVNSCISFHFFWSIP 414
            |:       ...::|..|:...::|.|:.:.:|| |..:|:|:.|:|..|:..:..........|
 Frog   238 ALTWALNYRTGSRLRGAVLTMAFKKILKLKNIKEKSMGELINVCSSDGQRMFEAAAVGSLLAGGP 302

  Fly   415 FKLFTTLYLLY--LQLG-AAFLAGVIFAALLIPINRWLAKRIGIFSSGLMTAKDARLSATTETMQ 476
              :...|.::|  :.|| ..||...:| .|..|...::::....|....::..|.|:....|.:.
 Frog   303 --IVAILGMIYNVIILGPTGFLGSAVF-ILFYPAMMFVSRLTAYFRRKCVSVTDERVQKMNEVLN 364

  Fly   477 GAKQIKINAWEDIFITKIRGLRQEELRFLSKRKYLDAMCVYFWATTPVLMCLLTFGVSVLMGNPL 541
            ..|.||:.||...|...::.:|:.|...|.:..|..::.|.......|:..:|||.|.:::|..|
 Frog   365 YIKFIKMYAWVKAFSQNVQKIRENERSILERAGYFQSITVGIAPIVVVIASVLTFSVHMILGYDL 429

  Fly   542 IASTTYTSVALLYMLIGPLNAFPWVLNGLIEAWVSIKRVQQLM------------DVPNLDYSSY 594
            .|:..:|.|.:...:...|...|:.:..|.||.||:.|.:.|.            ..|||
 Frog   430 TAAQAFTVVTVFNSMTFALKVTPFSVKSLSEASVSMDRFKSLFLMEEVHMVKKKPSSPNL----- 489

  Fly   595 YNPIMRGSGGSGAGDD-------APLDAPK----------------------ASVLQMKCASFCH 630
               |:.....:.|.|.       :|...||                      .:||..:......
 Frog   490 ---IIELKNATLAWDTTYASTQCSPKGTPKLKKGKKGVKGKKEKCSHEIEGSQAVLAEQKGHLLI 551

  Fly   631 DSDEQTSP------TPF-------RMKDINVDIKAGQLVCIEGPVGGGKSSFLSAIVANLQCTDG 682
            ||||..||      .|.       .:..|::||:.|:|:.|.|.||.||:|.:|||:..:...:|
 Frog   552 DSDEHPSPDEETKELPVINVKLQRALYSIDLDIEKGKLIGICGSVGSGKTSLISAILGQMTLLEG 616

  Fly   683 EVCVQELTTGFGYVPQSPWLQRGTIRDNIVWGAQFDEQWYKTVLHACALEEDLQIL-GGDLVGVG 746
            .:.|   :..|.||.|..|:...|:||||::|.:|||:.|..||:.|.|..||.|| .|||..:|
 Frog   617 SIAV---SGSFAYVAQQAWILNATLRDNILFGKEFDEEEYNAVLNVCCLRPDLAILPNGDLTEIG 678

  Fly   747 ENGRTLSGGQRARVALARAVYQDKKVYLLDDVLSSLDAHVARHIIKHCILRLLKHKTRIVVTRNI 811
            |.|..||||||.|::||||:|.|:.:|:|||.||:|||||..||....|.:.||.||.:.:|..:
 Frog   679 ERGANLSGGQRQRISLARALYSDRSIYILDDPLSALDAHVGNHIFNSAIRKHLKSKTILFITHQL 743

  Fly   812 QLFFHANQILQVKDGQL-----------LPSEY-------------------MTQSIELSLDEDA 846
            |.....:.::.:|:|.:           |..||                   :.::::.||.:..
 Frog   744 QYLVDCDDVIYMKEGCITERGTHEDLIKLNGEYAAIFNNFQLGDAPHIEQMNLKKNLKNSLKKPL 808

  Fly   847 DD-------EQEPTVRRRSVELSNQYDKKSLDSLLLEELREYGHLSGNVFTCYWKAVTSPLAFTV 904
            :.       ::|.||::...:|           :.||| :..|.:..:|:..|.::...|.||.:
 Frog   809 EKGNKAGSVKKEKTVKKEEGQL-----------MQLEE-KGKGSVPWSVYGAYIQSAGGPFAFLI 861

  Fly   905 LLSVVLMQL-TRNLSDAWLAYWVTE----TTLDPHKNDTSLDHILMRPTVGNETESGHTTKFYLS 964
            ::::.::.: :...|:.||:||:.:    ||:..| |:|         .|.|..:......||.:
 Frog   862 IMTLFVLNVGSTAFSNWWLSYWIKQGSGNTTVVVH-NET---------VVSNSMKDNPHVLFYTA 916

  Fly   965 IFTAIAVSNSLVTLARAFLFAYAGIKAAIFMHEKLLKKVMFAKFNFFDITSVGRILNRFSSDTNT 1029
            |:....|...|:...|..:|....::|:..:|::|.::::.:...|||.|..||:|||||.|.:.
 Frog   917 IYALSMVVMLLLKAVRGIVFVKGTLRASSRLHDELFRRILRSPMKFFDTTPTGRVLNRFSKDMDE 981

  Fly  1030 VDDSLPFILNILLAQLAGLVGALCVSLYAMPWLGLVIIPMVPIYLSLQQRYRHASRDIKRLSSNA 1094
            ||..|||...:.:..:..:...|.|..:..||..:.:.|:|.::..|....|...|::|||.:..
 Frog   982 VDVRLPFQAEMFVQNVILVFFCLGVISFVFPWFLVAVGPLVVLFTILHVVSRVFIRELKRLENIT 1046

  Fly  1095 MSPLYTHFTETLQGLTTIRSMRASPRFQRDFQVKLEESIKAQLTQSAAQQWLALRLQLLGTLLVG 1159
            .||..:|.|.::||||||.:......|...:|..|:.:.......:.|.:|||:||.::...|:.
 Frog  1047 QSPFLSHITSSIQGLTTIHAYSKGNEFLLRYQELLDNNQAPFYLFNCAMRWLAIRLDVISVSLIT 1111

  Fly  1160 GAGLLAAITASH-TTNPGLVGLCISYALSITGQLGDLLHAVAETEQELVAVERIDQY---LQLEE 1220
            ..||:  |...| ..:|...||.:|||:.:||.....:...:|||....:||||:.|   |.||.
 Frog  1112 TTGLM--IVLMHGNISPAYAGLAMSYAVQLTGLFQFTVRLASETEARFTSVERINHYIKTLALEA 1174

  Fly  1221 EQNASGSAEPPFGWPTQGVLSFREVQLSYREHLAPALRGITFQTEAFERIGIVGRTGAGKTSVLA 1285
            .......| ||..||.:|.:.|...::.|||:|...|:.::|..:..|:||||||||:||||:..
 Frog  1175 PARIKNKA-PPADWPQEGEIKFENAEMRYRENLPLVLKKVSFTIKPKEKIGIVGRTGSGKTSLGM 1238

  Fly  1286 ALLRVAPLTHGEIRLDQVNLKTLPLSVLRERIGVITQEPFLFEGTVRENLDPRHGFYDSEIWHAI 1350
            ||.|:..|:.|.|::|.|.:..:.|:.||.::.:|.|||.||.||||.||||...:.:.:||.|:
 Frog  1239 ALFRLVELSGGCIKIDGVKISDIGLADLRSKLSIIPQEPVLFSGTVRSNLDPFSQYSEEQIWDAL 1303

  Fly  1351 KNSAAATLLVQQLGGLDGKVETCGNNLSAGQRQLLCLARALLKNAKVVAIDEGTSNLDDESDLSI 1415
            :.:.....:.|....|:.:|...|.|.|.|:|||:|:||.||:..|::.:||.|:.:|.|:||.|
 Frog  1304 ERTHMKECVAQLPLKLETEVLENGENFSVGERQLMCIARVLLRRCKILILDEATAAMDTETDLLI 1368

  Fly  1416 QQALRNAFKSCTLLFIAHRLRGLHAMDRIIVLDDGRICEEGNPQSLASDSSTIFYGMLLA 1475
            |:.:|.||..||:|.|||||..:.:.|||:||..|::.|...|.:|.|:.:|.|:.|..|
 Frog  1369 QETIREAFAECTMLTIAHRLHTVLSCDRIMVLAQGQVMEYDTPSALLSNENTRFFSMFAA 1428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7806	NP_609207.1	MRP_assoc_pro	6..1472	CDD:188098	421/1420 (30%)
		ABC_membrane	328..560	CDD:294371	55/242 (23%)
		ABCC_MRP_domain1	621..827	CDD:213217	88/219 (40%)
		ABC_membrane	948..1192	CDD:279056	73/244 (30%)
		ABCC_MRP_domain2	1238..1458	CDD:213211	92/219 (42%)
abcc5	XP_012818083.1	PLN03130	101..1425	CDD:215595	410/1372 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D138195at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920