DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ostgamma and Magt1

DIOPT Version :9

Sequence 1:	NP_609204.2	Gene:	Ostgamma / 34137	FlyBaseID:	FBgn0032015	Length:	330	Species:	Drosophila melanogaster
Sequence 2:	NP_001363931.1	Gene:	Magt1 / 67075	MGIID:	1914325	Length:	343	Species:	Mus musculus

Alignment Length:	329	Identity:	165/329 - (50%)
Similarity:	233/329 - (70%)	Gaps:	12/329 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LLVVALFAI--YAAAQSKSKTGLSLSEKVQNLVDMNAKKPLLRFNGPKFREYVKSAPRNYSMIVM 74
            :..|||..:  ..:|.::.|..:.|||||..|::...|:|::|.||.|||..||:.|||||::||
Mouse    13 IAAVALLLVSKVPSASAQRKKEMVLSEKVSQLMEWANKRPVIRMNGDKFRRLVKAPPRNYSVVVM 77

  Fly    75 LTALAPSRQCQICRHAHDEFAIVANSYRFSSTYSNKLFFAMVDFDDGSEVFQLLRLNTAPVFMHF 139
            .|||...|||.:|:.|.:||.|:|||:|:|:.::|::||||||||:||:|||:|.:|:||.|::|
Mouse    78 FTALQLHRQCVVCKQADEEFQILANSWRYSNAFTNRIFFAMVDFDEGSDVFQMLNMNSAPTFINF 142

  Fly   140 PAKGKPKGADTMDIHRVGFAADSIAKFVAERTDIT--------IRIFRPPNYSGTVAMITLVALV 196
            |.|||||.|||.::...||:|:.||:::|:|||:.        ||:.|||||:|.:.:..|:|::
Mouse   143 PPKGKPKRADTYELQVRGFSAEQIARWIADRTDVNVSLPALQKIRVIRPPNYAGPLMLGLLLAVI 207

  Fly   197 GSFLYIRRNNLEFLYNKNLWGAIAVFFCFAMISGQMWNHIRGPPLVHKS-QNGGVAYIHGSSQGQ 260
            |..:|:||:|:|||:||..|...|:.|..||.||||||||||||..||: ..|.|.|||||||.|
Mouse   208 GGLVYLRRSNMEFLFNKTGWAFAALCFVLAMTSGQMWNHIRGPPYAHKNPHTGHVNYIHGSSQAQ 272

  Fly   261 LVVETYIVMFLNAMIVLGMILLIESGTPKAH-NKNRIMAMTGLVLLTVFFSFLLSVFRSKAQGYP 324
            .|.||:||:..|..:.|||:||.|:.|.... .|.|:|.:.|:.|:.:|||::||:||||..|||
Mouse   273 FVAETHIVLLFNGGVTLGMVLLCEAATSDMDIGKRRMMCIAGIGLVVLFFSWMLSIFRSKYHGYP 337

  Fly   325 YSFL 328
            ||||
Mouse   338 YSFL 341

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ostgamma	NP_609204.2	OST3_OST6	164..312	CDD:282594	75/157 (48%)
Magt1	NP_001363931.1	OST3_OST6	42..338	CDD:368099	150/295 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847004
Domainoid	1	1.000	370	1.000	Domainoid score	I903
eggNOG	1	0.900	-	-		E1_KOG2603
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	391	1.000	Inparanoid score	I1970
Isobase	1	0.950	-	0	Normalized mean entropy	S1891
OMA	1	1.010	-	-		QHG52911
OrthoDB	1	1.010	-	-		D1460433at2759
OrthoFinder	1	1.000	-	-		FOG0002554
OrthoInspector	1	1.000	-	-		otm43872
orthoMCL	1	0.900	-	-		OOG6_101708
Panther	1	1.100	-	-	O	PTHR12692
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1886
SonicParanoid	1	1.000	-	-		X2260
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	17	16.750