DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ostgamma and magt1

DIOPT Version :9

Sequence 1:	NP_609204.2	Gene:	Ostgamma / 34137	FlyBaseID:	FBgn0032015	Length:	330	Species:	Drosophila melanogaster
Sequence 2:	NP_955994.1	Gene:	magt1 / 324944	ZFINID:	ZDB-GENE-030131-3667	Length:	328	Species:	Danio rerio

Alignment Length:	329	Identity:	178/329 - (54%)
Similarity:	243/329 - (73%)	Gaps:	4/329 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LLHKTLLSGLLVVALFAIYAAAQSKSKTGLSLSEKVQNLVDMNAKKPLLRFNGPKFREYVKSAPR 67
            :|||.|:...|||.|..:....|.|.:|  .|||||..:::..:|:.::|.||.||:..|::.||
Zfish     1 MLHKLLIVVFLVVCLHDMRLNGQKKKET--LLSEKVSQMMEWVSKRAVVRLNGEKFKRLVRAHPR 63

  Fly    68 NYSMIVMLTALAPSRQCQICRHAHDEFAIVANSYRFSSTYSNKLFFAMVDFDDGSEVFQLLRLNT 132
            |||:|||.|||.|.|||.:||.|.:|:.|:|||:|:||.::|::||||||||:||:|||:|.:|:
Zfish    64 NYSVIVMFTALQPQRQCGVCRQADEEYQILANSWRYSSAFTNRIFFAMVDFDEGSDVFQMLNMNS 128

  Fly   133 APVFMHFPAKGKPKGADTMDIHRVGFAADSIAKFVAERTDITIRIFRPPNYSGTVAMITLVALVG 197
            ||.|::||||||||.|||.::...||||:.:|::||:|||:.||:.|||||:|.:.:..|:|.:|
Zfish   129 APTFINFPAKGKPKRADTYELQVRGFAAEQLARWVADRTDVHIRVIRPPNYAGPLMLGLLLAFIG 193

  Fly   198 SFLYIRRNNLEFLYNKNLWGAIAVFFCFAMISGQMWNHIRGPPLVHKSQN-GGVAYIHGSSQGQL 261
            |..|:||||||||:|||:|...|:.|...|.||||||||||||..||:.| |.|:|||||||.|.
Zfish   194 SLAYLRRNNLEFLFNKNVWAFSALCFVLIMTSGQMWNHIRGPPYAHKNPNTGQVSYIHGSSQAQF 258

  Fly   262 VVETYIVMFLNAMIVLGMILLIESGTPKAH-NKNRIMAMTGLVLLTVFFSFLLSVFRSKAQGYPY 325
            |.||:||:..||.:.:||:||.|:.|.... .|.:||.:.|:.|:.:|||:||||||:|..||||
Zfish   259 VAETHIVLLFNAAVTIGMVLLHEAATSGLDIVKRKIMCVAGIGLVVLFFSWLLSVFRAKYHGYPY 323

  Fly   326 SFLF 329
            ||||
Zfish   324 SFLF 327

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ostgamma	NP_609204.2	OST3_OST6	164..312	CDD:282594	80/149 (54%)
magt1	NP_955994.1	PDI_a_family	47..140	CDD:239259	55/92 (60%)
magt1	NP_955994.1	OST3_OST6	160..310	CDD:282594	80/149 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592213
Domainoid	1	1.000	371	1.000	Domainoid score	I853
eggNOG	1	0.900	-	-		E1_KOG2603
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	386	1.000	Inparanoid score	I1980
OMA	1	1.010	-	-		QHG52911
OrthoDB	1	1.010	-	-		D1460433at2759
OrthoFinder	1	1.000	-	-		FOG0002554
OrthoInspector	1	1.000	-	-		otm25986
orthoMCL	1	0.900	-	-		OOG6_101708
Panther	1	1.100	-	-	O	PTHR12692
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1886
SonicParanoid	1	1.000	-	-		X2260
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.800