DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ostgamma and ZK686.3

DIOPT Version :9

Sequence 1:	NP_609204.2	Gene:	Ostgamma / 34137	FlyBaseID:	FBgn0032015	Length:	330	Species:	Drosophila melanogaster
Sequence 2:	NP_498691.1	Gene:	ZK686.3 / 176089	WormBaseID:	WBGene00022793	Length:	331	Species:	Caenorhabditis elegans

Alignment Length:	335	Identity:	154/335 - (45%)
Similarity:	226/335 - (67%)	Gaps:	28/335 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 LFAIYAAAQSKSKTGLSLSEKVQNLVDMNAKKPLLRFNGPKFREYVKSAPRNYSMIVMLTALAPS 81
            |.|:|.:||.:     :|.:|||||||:.:::.:::||..|::..|:..|||||||||.|||:|.
Worm     2 LLAVYESAQQQ-----TLEDKVQNLVDLTSRQSIVKFNMDKWKTLVRMQPRNYSMIVMFTALSPG 61

  Fly    82 RQCQICRHAHDEFAIVANSYRFSSTYSN--KLFFAMVDFDDGSEVFQLLRLNTAPVFMHF-PAKG 143
            .||.||:.|:|||.|||||:|::|:..:  |:||.:||::|..::||.:.|||||:..|| |..|
Worm    62 VQCPICKPAYDEFMIVANSHRYTSSEGDRRKVFFGIVDYEDAPQIFQQMNLNTAPILYHFGPKLG 126

  Fly   144 KPKGADTMDIHRVGFAADSIAKFVAERTDITIRIFRPPNYSGTVAMITLVALVGSFLYIRRNNLE 208
            ..|..:.||..|.||.||:|.:|||::|::.:|:.|||||:..|.:...|||:...||::||:|:
Worm   127 AKKRPEQMDFQRQGFDADAIGRFVADQTEVHVRVIRPPNYTAPVVIALFVALLLGMLYMKRNSLD 191

  Fly   209 FLYNKNLWGAIAVFFCFAMISGQMWNHIRGPPLVHKSQN-GGVAYIHGSSQGQLVVETYIVMFLN 272
            ||:|:.:||.:.:...|..:||||||||||||.:..:.| ...::||||:|.||:.|||||..|.
Worm   192 FLFNRTVWGFVCLAITFIFMSGQMWNHIRGPPFMITNPNTKEPSFIHGSTQFQLIAETYIVGLLY 256

  Fly   273 AMIVLGMILLIESGTPKAHNKNR------------------IMAMTGLVLLTVFFSFLLSVFRSK 319
            |:|.:|.|.:.|: ..::::|:|                  .:|:.|||.:.|||||||||||||
Worm   257 ALIAIGFICVNEA-ADQSNSKDRKNAGKKLNPLSLLNIPTNTLAIAGLVCICVFFSFLLSVFRSK 320

  Fly   320 AQGYPYSFLF 329
            .:||||||||
Worm   321 YRGYPYSFLF 330

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ostgamma	NP_609204.2	OST3_OST6	164..312	CDD:282594	66/166 (40%)
ZK686.3	NP_498691.1	OST3_OST6	147..313	CDD:282594	66/166 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160164618
Domainoid	1	1.000	277	1.000	Domainoid score	I911
eggNOG	1	0.900	-	-		E1_KOG2603
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6937
Inparanoid	1	1.050	300	1.000	Inparanoid score	I1631
Isobase	1	0.950	-	0	Normalized mean entropy	S1891
OMA	1	1.010	-	-		QHG52911
OrthoDB	1	1.010	-	-		D1460433at2759
OrthoFinder	1	1.000	-	-		FOG0002554
OrthoInspector	1	1.000	-	-		oto17834
orthoMCL	1	0.900	-	-		OOG6_101708
Panther	1	1.100	-	-	LDO	PTHR12692
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1886
SonicParanoid	1	1.000	-	-		X2260
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	17	16.790