Protein Alignment CG7840 and SRD5A3

DIOPT Version :10

• Sequence 1: NP_609203.1
• Gene: CG7840 / 34136
• FlyBaseID: FBgn0032014
• Length: 326
• Species: Drosophila melanogaster
• Sequence 2: NP_078868.1
• Gene: SRD5A3 / 79644
• HGNCID: 25812
• Length: 318
• Species: Homo sapiens
• Alignment Length: 327
• Identity: 88/327 - (26%)
• Similarity: 147/327 - (44%)
• Gaps: 43/327 - (13%)

  Fly    21 INLLQMMFGTFIATIVFFGGLMTFVEKYLPNSI-------RQSFRYGKHSFKGETDPLVA-WLEV 77
            :|.|:.::.|..|..     |:|.:.:.||..:       :...||||......:.|... ..:|
Human    12 LNPLRAVWLTLTAAF-----LLTLLLQLLPPGLLPGCAIFQDLIRYGKTKCGEPSRPAACRAFDV 71

  Fly    78 PKSWFKHFYTFALFWSWLAFYVLVSTVREQKEAPEYVLQFLDIMGGGRSHRKVEIDSTTACVGAF 142
            ||.:|.|||..::.|:....:.|..::......|.::...|.|:|.      .:.......:.||
Human    72 PKRYFSHFYIISVLWNGFLLWCLTQSLFLGAPFPSWLHGLLRILGA------AQFQGGELALSAF 130

  Fly   143 M----LTLQCTRRFYETNFVQIFSKKSKINLSHYAVGYVHYFGAVIALLSNTSGFVRGSKPMEFS 203
            :    |.|...||.:|..:|.:|| ...|::..|..|.|:|....:.:||..        ||:..
Human   131 LVLVFLWLHSLRRLFECLYVSVFS-NVMIHVVQYCFGLVYYVLVGLTVLSQV--------PMDGR 186

  Fly   204 LDKLTSQQIL-------YLGVFFLAWQ--QQYASNMILVNLRKDPRTGSVKTEKHLLPKGGLFNL 259
            ...:|.:.:|       .||:....|.  .||..::||.||||: :.|.|....|.:|.|..|..
Human   187 NAYITGKNLLMQARWFHILGMMMFIWSSAHQYKCHVILGNLRKN-KAGVVIHCNHRIPFGDWFEY 250

  Fly   260 LSSPHMFLEVVMYFCIADLY-MPVRIWRLIFLWVASNQTINALLTHKWYQETFREYPKNRRAIIP 323
            :|||:...|:::|..:|..: .....|.|:...|..||.::|.|:|::|:..|..|||:|:|.:|
Human   251 VSSPNYLAELMIYVSMAVTFGFHNLTWWLVVTNVFFNQALSAFLSHQFYKSKFVSYPKHRKAFLP 315

  Fly   324 FL 325
            ||
Human   316 FL 317

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7840	NP_609203.1	ICMT	77..325	CDD:473892	73/261 (28%)
SRD5A3	NP_078868.1	ICMT	69..318	CDD:473892	75/265 (28%)