Protein Alignment CG7840 and SRD5A2

DIOPT Version :9

• Sequence 1: NP_609203.1
• Gene: CG7840 / 34136
• FlyBaseID: FBgn0032014
• Length: 326
• Species: Drosophila melanogaster
• Sequence 2: NP_000339.2
• Gene: SRD5A2 / 6716
• HGNCID: 11285
• Length: 254
• Species: Homo sapiens
• Alignment Length: 320
• Identity: 75/320 - (23%)
• Similarity: 118/320 - (36%)
• Gaps: 108/320 - (33%)

  Fly    33 ATIVFFGGLMTFVEKYLPNSIRQSFRYGKH--SFKGETDPLVAWLEVPKSWF-KHFYTFALFWSW 94
            ||:|..|.|..:|.|  |:.      ||||  |.|    |....|....:|| :...:||:
Human    15 ATLVALGALALYVAK--PSG------YGKHTESLK----PAATRLPARAAWFLQELPSFAV---- 63

  Fly    95 LAFYVLVSTVREQKEAPEYVL--QFLDIMGGGRSHRKVEIDSTTACVGAFMLTLQCTRRFYETNF 157
                            |..:|  |.|.:.|.               .|..:|.|.|...|:.| |
Human    64 ----------------PAGILARQPLSLFGP---------------PGTVLLGLFCLHYFHRT-F 96

  Fly   158 VQIFSKKSKINLSHYAVGYVHYFGAVIALLSNTSGFVRGSKPMEFSLDKLTSQQILY-------- 214
            |.....:.:            .:.|::.|  ..:.|..|:       ..|....::|
Human    97 VYSLLNRGR------------PYPAILIL--RGTAFCTGN-------GVLQGYYLIYCAEYPDGW 140

  Fly   215 -------LGV--FFLAWQQQYASNMILVNLRKDPRTGSVKTEKHLLPKGGLFNLLSSPHMFLEVV 270
                   |||  |.|.......|:.||..|||   .|.:   .:.:|:||||..:|..:...|::
Human   141 YTDIRFSLGVFLFILGMGINIHSDYILRQLRK---PGEI---SYRIPQGGLFTYVSGANFLGEII 199

  Fly   271 MY--FCIADLYMPV---RIWRLIFLWVASNQTINALLTHKWYQETFREYPKNRRAIIPFL 325
            .:  :.:|...:|.   ..:.|.||      .:.|...|::|.:.|.:|||:|:|:|||:
Human   200 EWIGYALATWSLPALAFAFFSLCFL------GLRAFHHHRFYLKMFEDYPKSRKALIPFI 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7840	NP_609203.1	PEMT	77..325	CDD:304400	58/272 (21%)
SRD5A2	NP_000339.2	Steroid_dh	105..254	CDD:251363	42/182 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1574389at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1297
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.920