DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7840 and B0024.13

DIOPT Version :9

Sequence 1:	NP_609203.1	Gene:	CG7840 / 34136	FlyBaseID:	FBgn0032014	Length:	326	Species:	Drosophila melanogaster
Sequence 2:	NP_001256209.1	Gene:	B0024.13 / 179438	WormBaseID:	WBGene00007102	Length:	309	Species:	Caenorhabditis elegans

Alignment Length:	277	Identity:	99/277 - (35%)
Similarity:	150/277 - (54%)	Gaps:	22/277 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 YGKHSFKGETDPLVAWLEVPKSWFKHFYTFALFWSWLAFYVLVSTVREQKEAPEY----VLQFLD 119
            |||.:.:.|.:.||..:.|||.||||||...|    |..::.:.||......|.|    ||:.|.
Worm    46 YGKAADQQEDNSLVEKISVPKKWFKHFYAIGL----LTLFICLHTVHSLIYNPNYLHPVVLKILA 106

  Fly   120 IMGGGRSHRKVEIDSTTACVGAFMLTLQCTRRFYETNFVQIFSKKSKINLSHYAVGYVHYFGAVI 184
            .:  .||:....|..:|:.:...:::|...||.|||.||.::| .|::||.|||||.|||....|
Worm   107 TL--TRSYSIPPITPSTSILALLLISLHVARRLYETIFVSVYS-DSRMNLFHYAVGIVHYIILPI 168

  Fly   185 ALLSNTSGFVRGSKPMEFSLDKLTSQQILYLGVFFLA-WQQQYASNMILVNLRKDPRTGSVKTEK 248
            :::..|.|.......:..|:|.::..|.....:|::. |:|...:..| .|.||.|| |.::...
Worm   169 SIMCETQGVASKLPQLHVSIDDISLTQWAGAVLFWICNWKQHQLAEQI-ANTRKGPR-GLIRNYA 231

  Fly   249 HLLPKGGLFNLLSSPHMFLEVVMY----FCIADLYMPVRIWRLIFLWVASNQTINALLTHKWYQE 309
            :.:..||.|||:|.||...|:.:|    ..|.|.|    ::|.|.::|..|||..||:||.||.:
Worm   232 YGICFGGWFNLVSCPHFLFEICIYLSLFLVIPDAY----VYRFIIMFVCINQTFAALITHSWYHK 292

  Fly   310 TFREYPKNRRAIIPFLL 326
            ||.:|||:|:|:||::|
Worm   293 TFPKYPKSRKALIPYVL 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7840	NP_609203.1	PEMT	77..325	CDD:304400	92/256 (36%)
B0024.13	NP_001256209.1	PEMT	189..309	CDD:304400	46/125 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160163724
Domainoid	1	1.000	83	1.000	Domainoid score	I5368
eggNOG	1	0.900	-	-		E1_KOG1640
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41385
Inparanoid	1	1.050	162	1.000	Inparanoid score	I2846
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54685
OrthoDB	1	1.010	-	-		D1574389at2759
OrthoFinder	1	1.000	-	-		FOG0002741
OrthoInspector	1	1.000	-	-		oto19668
orthoMCL	1	0.900	-	-		OOG6_103960
Panther	1	1.100	-	-	LDO	PTHR14624
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2089
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.800