Protein Alignment Scgalpha and SGCA

DIOPT Version :10

• Sequence 1: NP_001260246.1
• Gene: Scgalpha / 34135
• FlyBaseID: FBgn0032013
• Length: 453
• Species: Drosophila melanogaster
• Sequence 2: NP_000014.1
• Gene: SGCA / 6442
• HGNCID: 10805
• Length: 387
• Species: Homo sapiens
• Alignment Length: 341
• Identity: 81/341 - (23%)
• Similarity: 146/341 - (42%)
• Gaps: 59/341 - (17%)

  Fly     6 LIVVVLA-LICNEVQGLKLQANVGELFTYKIEPQLFNWTHQVI----SQQFRYRPSLKNYPDLPS 65
            |:||:|| |...|.|...|...||.:|.:.::.:.|....:.:    :....|...|:.:||||.
Human    10 LLVVLLAGLGDTEAQQTTLHPLVGRVFVHTLDHETFLSLPEHVAVPPAVHITYHAHLQGHPDLPR 74

  Fly    66 WMRYMYSHEYHAGFLYGTPPASSAGKDLSLDVVALNRQNYETRRVVVTMFVAHK----FPTPNVV 126
            |:||.....:|.|||||:......|..: ::|.|.||.:::|.|..:.:.:...    .|.....
Human    75 WLRYTQRSPHHPGFLYGSATPEDRGLQV-IEVTAYNRDSFDTTRQRLVLEIGDPEGPLLPYQAEF 138

  Fly   127 QMKINNLNWVHLMDPGRRENLRNIFRN---DLWPNSKEDLSVVFMESAVNMGGRLPLRPQ-QREG 187
            .::.::...|....|..|      |.:   .||  ...:|.::.:.||::.|||:||..: ::||
Human   139 LVRSHDAEEVLPSTPASR------FLSALGGLW--EPGELQLLNVTSALDRGGRVPLPIEGRKEG 195

  Fly   188 VIVHVGSFAQFSPRLQEL---QEEVRPLYKLPSCTYKRTSVQKIFENVG--FKLDWCAFRMVGME 247
            |.:.|||.:.||..|:.:   ....|       |...:..:...::.:.  |::|||...:|...
Human   196 VYIKVGSASPFSTCLKMVASPDSHAR-------CAQGQPPLLSCYDTLAPHFRVDWCNVTLVDKS 253

  Fly   248 SPTEILFHSGKQNEQQMPDDLNQRQEDRWMGIARED--------VPERNYIDEFAFAFAIPGMIF 304
            .|.       ..:|...|.|          ||...|        .|:|:::.:......:|.::.
Human   254 VPE-------PADEVPTPGD----------GILEHDPFFCPPTEAPDRDFLVDALVTLLVPLLVA 301

  Fly   305 AILIGMLSAVLCFQHE 320
            .:|..:|:.|:|.:.|
Human   302 LLLTLLLAYVMCCRRE 317

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Scgalpha	NP_001260246.1	Sarcoglycan_2	2..410	CDD:461668	81/341 (24%)
SGCA	NP_000014.1	Sarcoglycan_2	21..347	CDD:461668	75/330 (23%)