Protein Alignment Scgalpha and sgca-1

DIOPT Version :10

• Sequence 1: NP_001260246.1
• Gene: Scgalpha / 34135
• FlyBaseID: FBgn0032013
• Length: 453
• Species: Drosophila melanogaster
• Sequence 2: NP_001360086.1
• Gene: sgca-1 / 180946
• WormBaseID: WBGene00019227
• Length: 458
• Species: Caenorhabditis elegans
• Alignment Length: 491
• Identity: 112/491 - (22%)
• Similarity: 195/491 - (39%)
• Gaps: 117/491 - (23%)

  Fly     1 MKFLNLIVVVLALICNEVQGLKLQANV----GELFTYKI-EPQLFNWTHQVISQQFRYRPSLKNY 60
            ::.|:..:..:.|:....:..|...:|    |:.|.:.: ....|..|.:|     ::..:|...
 Worm     3 IRLLDFSIFSILLLFRTSKSFKAPTHVTATKGKFFVHTLHSAHFFPSTVKV-----KWEATLNKK 62

  Fly    61 PDLPSWMRYMYSHEYHAGFLYGTPPASSAGKDLSLDVVALNRQNYE-TRRVVVTMFV---AHKFP 121
            |.||:|:|.:.|......:|.|||..:.  :.::|.|:|....|:: .:|:||...|   .::..
 Worm    63 PALPNWLRLLPSRHPEIAYLIGTPVTNV--QHVTLHVIAKRLDNFDIQQRMVVINLVEDSLYQGN 125

  Fly   122 TPNVVQMKINNLNWVHLMDPGRRE------NLRNIFRND-------------LWPNSKEDLSVVF 167
            |..|.::.||.|:...|:....|:      :|||.||..             :.|..||.   :|
 Worm   126 TQQVFELPINGLDVEDLVSNRDRKISQLENSLRNTFRGRNVNPYIAGVRSRYIIPRGKEH---IF 187

  Fly   168 MESAVNMGGRLPLRPQQREGVIVHVGSFAQFSPRLQELQEEVRPLYKLPS-CTYKRTSVQKIFEN 231
            ..|.               |.:|:||:..:|.|....:   |..|..:|. |:...:.|...:..
 Worm   188 KNSF---------------GTMVYVGTQQKFYPGTMSI---VHNLQTMPEFCSNPSSVVMNKYFA 234

  Fly   232 VGFKLDWC--AFRMVGM---ESPTEILFHSGKQNEQQ------MPD-DLNQRQEDRWMGIAREDV 284
            ..|.:|||  |.|.:..   |...|::     ::||:      .|| :||::.|.
 Worm   235 PTFPVDWCNVAVRNISSLEGEGIDELI-----KDEQEEKLTKANPDQNLNEKPEQ---------- 284

  Fly   285 PERNYIDEFAFAFAIPGMIFAILIG-----MLSAVLCF----QHEKFYDPHS------EFFFA-- 332
            |.|.........|:|  ::|||::|     :.:.||.|    :.:|:.|..:      ||...
 Worm   285 PPRELYGYSEHGFSI--VLFAIILGVSILFVFALVLIFFGSREGQKWRDDKTSGETLGEFISIRD 347

  Fly   333 NIFHICEESCAPQSAS----SDSGADDGSES--SSNSDYPMASTVQMVQCSDSKSNQPITTLKSL 391
            |...:.|.|...|..|    ::|.|..|..|  .|.|..|..|..:..: |.|:.|....|::.|
 Worm   348 NQKKLRELSLQRQLLSMGPDTNSTAPSGIHSYLQSRSRAPSTSIARFSK-SASRLNDKEDTIELL 411

  Fly   392 KDPNFLLDNTSMRSQSPNNSFYQLDCGNS-SIYARP 426
            ..    :|:..:..|:...:..|  ||:| .:|..|
 Worm   412 PS----VDHVPVGKQTVAEAAKQ--CGSSLHLYRNP 441

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Scgalpha	NP_001260246.1	Sarcoglycan_2	2..410	CDD:461668	106/471 (23%)
sgca-1	NP_001360086.1	Sarcoglycan_2	2..>288	CDD:461668	72/327 (22%)
		CADG	29..118	CDD:214795	24/95 (25%)