Protein Alignment Btk and AT1G73660

DIOPT Version :10

• Sequence 1: NP_476745.1
• Gene: Btk / 34132
• FlyBaseID: FBgn0003502
• Length: 786
• Species: Drosophila melanogaster
• Sequence 2: NP_177507.1
• Gene: AT1G73660 / 843701
• AraportID: AT1G73660
• Length: 1030
• Species: Arabidopsis thaliana
• Alignment Length: 658
• Identity: 155/658 - (23%)
• Similarity: 253/658 - (38%)
• Gaps: 156/658 - (23%)

  Fly   234 SSPAQNSTRSISPNSS------TTNSQFSLQHNSSGSLGGGVGGGLGGGGSLGLGGGGGGGGSCT 292
            :||..|.:..::.:|:      ..|::|....:.|.:...|.....||||.|
plant   401 ASPGDNDSIHVASSSNGIESSYEENTEFRTGEHRSSTKSSGERNQSGGGGDL------------- 452

  Fly   293 PTSLQPQSSLTTFKQ------------SPTLLNGNGTLLDANMPGGIPTPGTPNSKAKDNSHFV- 344
              .:.|..|....|.            |...::....:...:...|:.:|.....|.||.|.::
plant   453 --IVHPNISREDVKNQKKVEKAPFQNLSSRPIHSFTHMRSPSWTEGVSSPAAQRMKVKDVSQYMI 515

  Fly   345 -----------KL--------VVA-------LYPFK---AIEGGDLSLEKNAEYEVIDDSQEHWW 380
                       ||        |||       :||.:   .:|..:.:..|....:.::.:||  .
plant   516 DAAKENPRLAQKLHDVLLESGVVAPPNLFSEVYPQQLEATVESKNSTEAKKERGKDLETTQE--G 578

  Fly   381 KVKDALGNVGYIPSNYVKPKALLGLERYEWYVGDMSRQRAESLLKQGDKEGCFVVRKSSTKGLYT 445
            :.::..|.|.::|.          |.|.:.......::....::.|.|....   ..|||:  |.
plant   579 RHQNGFGPVRFLPP----------LPRVQSKTNAHDQRDNGKVVSQSDSSHS---EASSTE--YA 628

  Fly   446 LSLHTKVPQSHVKHYHIKQNARCEYYLSEKHCCE---------TIPDLI---------------- 485
            .::...|..:.|....:...|..:...|:....|         |...::
plant   629 RTVPAAVAAAAVVASSMVAAAAAKSANSDSSPIELPAAAAATATAAAVVATAAAVSRQLELGSNS 693

  Fly   486 ----------------NYHRHNSGGLACRLKS-------SPCDRPVPPTAGLSHDK--WEIHPME 525
                            :.|..||||.....||       |.||       .:|..:  ||    |
plant   694 DGDDGSGGHEPQGSGDSNHGPNSGGERISDKSIGNESSKSDCD-------DVSDCEILWE----E 747

  Fly   526 LMLMEELGSGQFGVVRRGKWRGSIDTAVKMMKEGTMSE--DDFIEEAKVMTKLQHPNLVQLYGVC 588
            :.:.|.:|.|.:|.|.||.|.|:.....|.:.:....|  ::|..|.::|.||:|||:|...|..
plant   748 ITVGERIGLGSYGEVYRGDWHGTEVAVKKFLDQDLTGEALEEFRSEVRIMKKLRHPNIVLFMGAV 812

  Fly   589 SKHRPIYIVTEYMKHGSLLNYLRRHEKTLIGNMGLLLDMCIQVSKGMTYLERHN--YIHRDLAAR 651
            ::...:.||||::..|||...:.|....|  :....|.|.:..::||.||...|  .:||||.:.
plant   813 TRPPNLSIVTEFLPRGSLYRLIHRPNNQL--DERRRLRMALDAARGMNYLHSCNPMIVHRDLKSP 875

  Fly   652 NCLVGSENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEVLNYTRFSSKSDVWAYGVLMWEI 716
            |.||....||||.||||:| :....|.||..|....:|..||||.......|.||::|||::||:
plant   876 NLLVDKNWVVKVCDFGLSR-MKHSTYLSSKSTAGTAEWMAPEVLRNEPADEKCDVYSYGVILWEL 939

  Fly   717 FTCGKMPYGRLKNTEVVERV----QRGIILEKPKSCAKEIYDVMKLCWSHGPEERPAFRVLMDQL 777
            ||. :.|:|::...:||..|    :|   |:.|......|.|::..||....:.||:|..:|..|
plant   940 FTL-QQPWGKMNPMQVVGAVGFQHRR---LDIPDFVDPAIADLISKCWQTDSKLRPSFAEIMASL 1000

  Fly   778 ALVAQTLT 785
            ..:.:.:|
plant  1001 KRLQKPVT 1008

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Btk	NP_476745.1	PH_Btk	44..222	CDD:269944
		SH3_Tec_like	346..399	CDD:212702	13/70 (19%)
		SH2_Tec_family	403..505	CDD:198188	22/149 (15%)
		PTKc_Tec_like	521..778	CDD:173637	89/264 (34%)
AT1G73660	NP_177507.1	EDR1	178..382	CDD:433922
		STKc_MAP3K-like	754..1000	CDD:270901	87/252 (35%)