DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Btk29A and SERK1

DIOPT Version :9

Sequence 1:	NP_001097121.1	Gene:	Btk29A / 34132	FlyBaseID:	FBgn0003502	Length:	786	Species:	Drosophila melanogaster
Sequence 2:	NP_177328.1	Gene:	SERK1 / 843513	AraportID:	AT1G71830	Length:	625	Species:	Arabidopsis thaliana

Alignment Length:	598	Identity:	138/598 - (23%)
Similarity:	215/598 - (35%)	Gaps:	192/598 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   294 TSLQPQSSLTTFKQSPTLLNGNGTLLDANMPGGIP------TPGTPNSKAKDNSHFVKLVVALYP 352
            |.:.|.:.|.::  .|||:|              |      |....||..:.:....:|...|.|
plant    39 TLVDPNNVLQSW--DPTLVN--------------PCTWFHVTCNNENSVIRVDLGNAELSGHLVP 87

  Fly   353 FKAIEGGDLSLEKNAEY-EVIDDSQEHWWKVKDALGNV-GYIPSNYVKPKALLGLERYEWYVGDM 415
                   :|.:.||.:| |:..:             |: |.||||...   |..|...:.|:...
plant    88 -------ELGVLKNLQYLELYSN-------------NITGPIPSNLGN---LTNLVSLDLYLNSF 129

  Fly   416 SRQRAESLLKQGDKEGCFVVRKSSTKGLYTLSLHTKVPQSHVKHYHIKQNARCEYYLSEKHCCET 480
            |....|||.|. .|.....:..:|..|...:|| |.:....|..            ||......:
plant   130 SGPIPESLGKL-SKLRFLRLNNNSLTGSIPMSL-TNITTLQVLD------------LSNNRLSGS 180

  Fly   481 IPDLINYHRH------NSGGLACRLKSSPCD-----RPVPP-----------------------T 511
            :||..::...      |:..|...:.|.||.     .|.||                       .
plant   181 VPDNGSFSLFTPISFANNLDLCGPVTSHPCPGSPPFSPPPPFIQPPPVSTPSGYGITGAIAGGVA 245

  Fly   512 AG---------LSHDKW------------------EIH--------PMELMLMEE-------LGS 534
            ||         ::...|                  |:|        ..||.:..:       ||.
plant   246 AGAALLFAAPAIAFAWWRRRKPLDIFFDVPAEEDPEVHLGQLKRFSLRELQVASDGFSNKNILGR 310

  Fly   535 GQFGVVRRGKWRGSIDTAVKMMKEGTM--SEDDFIEEAKVMTKLQHPNLVQLYGVCSKHRPIYIV 597
            |.||.|.:|:.......|||.:||...  .|..|..|.::::...|.||::|.|.|.......:|
plant   311 GGFGKVYKGRLADGTLVAVKRLKEERTPGGELQFQTEVEMISMAVHRNLLRLRGFCMTPTERLLV 375

  Fly   598 TEYMKHGSLLNYLRR------------HEKTLIGNMGLLLDMCIQVSKGMTYLERH---NYIHRD 647
            ..||.:||:.:.||.            .::..:|:           ::|::||..|   ..||||
plant   376 YPYMANGSVASCLRERPPSQPPLDWPTRKRIALGS-----------ARGLSYLHDHCDPKIIHRD 429

  Fly   648 LAARNCLVGSENVVKVADFGLARYVLD--DQY--TSSGGTKFPIKWAPPEVLNYTRFSSKSDVWA 708
            :.|.|.|:..|....|.|||||: ::|  |.:  |:..||   |....||.|:..:.|.|:||:.
plant   430 VKAANILLDEEFEAVVGDFGLAK-LMDYKDTHVTTAVRGT---IGHIAPEYLSTGKSSEKTDVFG 490

  Fly   709 YGVLMWEIFTCGKMPY--GRLKNTEVVERVQ--RGIILEKPKSC--------------AKEIYDV 755
            ||:::.|:.| |:..:  .||.|.:.|..:.  :|::.||....              .:::..|
plant   491 YGIMLLELIT-GQRAFDLARLANDDDVMLLDWVKGLLKEKKLEMLVDPDLQTNYEERELEQVIQV 554

  Fly   756 MKLCWSHGPEERP 768
            ..||....|.|||
plant   555 ALLCTQGSPMERP 567

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Btk29A	NP_001097121.1	PH_Btk	44..222	CDD:269944
		SH3_Tec_like	346..399	CDD:212702	14/54 (26%)
		SH2_Tec_family	403..505	CDD:198188	22/107 (21%)
		PTKc_Tec_like	521..778	CDD:173637	82/302 (27%)
		Pkinase_Tyr	526..777	CDD:285015	80/289 (28%)
SERK1	NP_177328.1	PLN00113	2..>182	CDD:215061	42/195 (22%)
		leucine-rich repeat	73..94	CDD:275380	4/27 (15%)
		leucine-rich repeat	95..118	CDD:275380	9/38 (24%)
		leucine-rich repeat	119..142	CDD:275380	7/23 (30%)
		leucine-rich repeat	143..166	CDD:275380	5/23 (22%)
		STK_BAK1_like	308..579	CDD:271134	79/276 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	119	1.000	Inparanoid score	I1986
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050