DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Btk29A and PERK7

DIOPT Version :9

Sequence 1:NP_001097121.1 Gene:Btk29A / 34132 FlyBaseID:FBgn0003502 Length:786 Species:Drosophila melanogaster
Sequence 2:NP_175353.1 Gene:PERK7 / 841351 AraportID:AT1G49270 Length:699 Species:Arabidopsis thaliana


Alignment Length:575 Identity:125/575 - (21%)
Similarity:203/575 - (35%) Gaps:188/575 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   229 NPSNGSS------PAQNSTRSISPNSSTTNSQFSLQHNSSGSLGGGVGGGLGGGGSLGLGGGGGG 287
            |.|:|||      |:.:|::|.||...:|:.  ..|.:::|:.|.......|..||  .|.||..
plant    70 NSSDGSSSSSPPPPSDSSSQSQSPPPPSTSP--PQQSDNNGNKGNNNENNKGNDGS--SGDGGNK 130

  Fly   288 GGSCTPTSLQPQSSLTTFKQSPTLLNGNGTLLDANMPGGIPTPGTPNSKAKDNSH---------- 342
            ..|.||......|..::..|..:|                 .|.|.||.:..:|:          
plant   131 NMSHTPPPPSKTSDHSSHSQPRSL-----------------APPTSNSGSNSSSNDGLNIGAVIG 178

  Fly   343 --------FVKLVVA-----------------------LYPFKAIEGGDLSLEKNAEYEVIDDSQ 376
                    |:.:::.                       .|| ....|||....:||..:    .|
plant   179 LVAAAGILFIVMILLCVCCFRKKKKKSKLDQMPYYGSNAYP-AGKTGGDQYYNQNAATQ----QQ 238

  Fly   377 EHWWKVKDALGNV----GYIPSNYVK----------------PKALLGLERYEWYVGDMSRQRAE 421
            :| :...|.:.|:    |.:.:|:|.                |..:.|               ..
plant   239 QH-YNQNDHIVNLPPPPGSMGTNWVSSPPPPPPGNWQPMPSPPAPVSG---------------GA 287

  Fly   422 SLLKQGDKEGCFVVRKSSTKGLYTLSLHTKVPQSHVKHYHIKQNARCEYYLSEKHCCETIPDLIN 486
            ::::.|:....|      :.|.|..||...                                   
plant   288 NVIQSGEMSSNF------SSGPYAPSLPPP----------------------------------- 311

  Fly   487 YHRHNSGGLACRLKSSPCDRPVPPTAGLSHDKWEIHPMELMLMEELGSGQFGVVRRGKWRGSIDT 551
               |.|..|.....:...:.....|.|.|.|:.            ||.|.||.|.:|......:.
plant   312 ---HPSVALGFNNSTFTYEELASATQGFSKDRL------------LGQGGFGYVHKGILPNGKEI 361

  Fly   552 AVKMMKEGT-MSEDDFIEEAKVMTKLQHPNLVQLYGVCSK---HRPIYIVTEYMKHGSLLNYLRR 612
            |||.:|.|: ..|.:|..|.::::::.|.:||.|.|.||.   .|  .:|.|::.:.:|      
plant   362 AVKSLKAGSGQGEREFQAEVEIISRVHHRHLVSLVGYCSNAGGQR--LLVYEFLPNDTL------ 418

  Fly   613 HEKTLIGNMGLLLD------MCIQVSKGMTYLERH---NYIHRDLAARNCLVGSENVVKVADFGL 668
             |..|.|..|.::|      :.:..:||:.||...   ..||||:.|.|.|:......|||||||
plant   419 -EFHLHGKSGTVMDWPTRLKIALGSAKGLAYLHEDCHPKIIHRDIKASNILLDHNFEAKVADFGL 482

  Fly   669 ARYVLDDQYTSSGGTKFPIKWAPPEVLNYTRFSSKSDVWAYGVLMWEIFTCGKMP 723
            |:...|:....|........:..||..:..:.:.||||:::||::.|:.| |:.|
plant   483 AKLSQDNNTHVSTRVMGTFGYLAPEYASSGKLTEKSDVFSFGVMLLELIT-GRGP 536

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Btk29ANP_001097121.1 PH_Btk 44..222 CDD:269944
SH3_Tec_like 346..399 CDD:212702 14/95 (15%)
SH2_Tec_family 403..505 CDD:198188 10/101 (10%)
PTKc_Tec_like 521..778 CDD:173637 64/216 (30%)
Pkinase_Tyr 526..777 CDD:285015 64/211 (30%)
PERK7NP_175353.1 PKc_like 342..612 CDD:389743 64/205 (31%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 119 1.000 Inparanoid score I1986
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.050

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