Protein Alignment Btk and AT5G49470

DIOPT Version :10

• Sequence 1: NP_476745.1
• Gene: Btk / 34132
• FlyBaseID: FBgn0003502
• Length: 786
• Species: Drosophila melanogaster
• Sequence 2: NP_974914.2
• Gene: AT5G49470 / 835007
• AraportID: AT5G49470
• Length: 831
• Species: Arabidopsis thaliana
• Alignment Length: 876
• Identity: 201/876 - (22%)
• Similarity: 310/876 - (35%)
• Gaps: 270/876 - (30%)

  Fly    85 RRRERGRIHLKGVRLVEEATVSGE------GGDPFAP------DGYPF--QVGYCEISASA---- 131
            |..|..:.|||  |.:....||.|      ...|..|      ||.|.  :.|......::
plant    16 RELEESQEHLK--REMSRLKVSAEMKQRSHSASPQRPVRRNSNDGTPMWRKTGAASFRHASPLRK 78

  Fly   132 NSHQLENGNGGGSGVGIEGQQSGRAVPQYTLYVIANSEKERSEWIRAIRQVCE--DSNTPKSYRY 194
            .||....|.||      |||.:|:.           ::|:....::::.|...  |.|....:
plant    79 ESHAKVAGGGG------EGQSAGKF-----------TDKQYLNILQSMAQAVHVFDLNGQIIF-- 124

  Fly   195 HPGLWSGKKWSCCKGLSRTTFGCRAAAHWREA-NNNPSN------GSSPAQNSTRSISPNSSTT- 251
                     |:   .::...:|..|:    || ..:|.:      .:|.|||.||..|...|.|
plant   125 ---------WN---SMAEKLYGFSAS----EALGKDPIDILVDVQDASVAQNITRRCSSGESWTG 173

  Fly   252 --------NSQFSL------QHNSSGSLGGGV----GGGL-----GGGGSLGLGGGGGGGGSCTP 293
                    ..:||:      .::..|.|.|.:    ...|     |.......|..|....|...
plant   174 EFPVKNKAGERFSVVTTMSPSYDDDGCLIGIICITNDSALFQDPRGSPAKTRRGQEGETSFSRVT 238

  Fly   294 TSLQPQ----------SSLTTFKQSP---------TLLNGN--------GTLLDANMPGGIPTPG 331
            :|:..:          |.|....|.|         :.|.||        |....||:.|     |
plant   239 SSVASKLGLDSKEAVVSKLGLDSQQPIQVAIASKISDLVGNKVKSKMRAGDNNAANLEG-----G 298

  Fly   332 TPNSKAKDNSHFVKLVVALYPFKAIEGGD--------------LSLEKNAEYEVIDDSQEHWWKV 382
            :.:|...|...|...........|..|.|              |..::.|..:...||.:.
plant   299 SGDSHQSDQGFFDAAFADRREDAATSGADTPRGDFIQSPFGVFLRSDEKASTKPFRDSSDE---- 359

  Fly   383 KDALGNVGYIPSNYVKPKALLGLERYEWYVGDMSRQRAESLLKQGDKEG-CFVVRKSSTKGLYTL 446
                     ...|.|.||.|.. :..||.|                |:| .:..:.:..:||...
plant   360 ---------SDGNSVVPKTLTS-KAEEWMV----------------KKGLSWPWKGNEREGLEGR 398

  Fly   447 SLHTKVP-----QSHVKHYHIKQNARCEYYLSEKHCCETI-----------PDLINYHRHNSGGL 495
            ..|:..|     |...:.|....|...:   ||...||:|           ...:|.:..:|...
plant   399 RSHSVWPWVRNEQQKQQAYQSNSNHSVK---SESQACESIKASSNEPMGYWSSSVNVNSTSSSSS 460

  Fly   496 ACRLKSSPCDRPVPPTAGLSHD-KWEIHPMELMLMEELGSGQFGVVRRGKWRGSIDTAVKMMKEG 559
            .....||..::....:..|.:: .||    :|.:.|::|.|..|.|..|.|.|| |.|||:..:.
plant   461 CGSTSSSVMNKVDMDSDCLDYEILWE----DLTIGEQIGQGSCGTVYHGLWFGS-DVAVKVFSKQ 520

  Fly   560 TMSED---DFIEEAKVMTKLQHPNLVQLYGVCSKHRPIYIVTEYMKHGSLLNY-----------L 610
            ..||:   .|.:|..:|.:|:|||::...|..:..:.:.||||::....|:..           |
plant   521 EYSEEIITSFRQEVSLMKRLRHPNVLLFMGAVTSPQRLCIVTEFLPRFGLITLANITLPFVLFEL 585

  Fly   611 RRHEKTLI-----------------------GNMGL----------LLDMCIQV----------- 631
            |.....|.                       |::.:          .||..||:
plant   586 RGQNSDLPYQITFAVEVSSVCCRGTRQNWIGGDVSIWPRIFYLAYYSLDSLIQLLYLVYNMLHIF 650

  Fly   632 -------SKGMTYLERHN----YIHRDLAARNCLVGSENVVKVADFGLARYVLDDQYTSSGGTKF 685
                   ::||.||  |:    .|||||.:.|.||.....||||||||:|...:...|:..|...
plant   651 LTYFFAQARGMNYL--HHCTPPIIHRDLKSSNLLVDKNWTVKVADFGLSRIKHETYLTTKTGRGT 713

  Fly   686 PIKWAPPEVLNYTRFSSKSDVWAYGVLMWEIFTCGKMPYGRLKNTEVVERV----QRGIILEKPK 746
            | :|..||||.......||||:::||::||:.| .|:|:..|...:|:..|    ||   ||.||
plant   714 P-QWMAPEVLRNEAADEKSDVYSFGVILWELVT-EKIPWESLNAMQVIGAVGFMNQR---LEVPK 773

  Fly   747 SCAKEIYDVMKLCWSHGPEERPAFRVLMDQL 777
            :...:...:|:.||...|::||:|:.:|::|
plant   774 NVDPQWISLMESCWHSEPQDRPSFQEIMEKL 804

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Btk	NP_476745.1	PH_Btk	44..222	CDD:269944	31/156 (20%)
		SH3_Tec_like	346..399	CDD:212702	9/66 (14%)
		SH2_Tec_family	403..505	CDD:198188	21/118 (18%)
		PTKc_Tec_like	521..778	CDD:173637	96/330 (29%)
AT5G49470	NP_974914.2	PAS	101..>210	CDD:441804	23/126 (18%)
		STKc_MAP3K-like	494..804	CDD:270901	93/317 (29%)