DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Btk29A and AT5G18910

DIOPT Version :9

Sequence 1:	NP_001097121.1	Gene:	Btk29A / 34132	FlyBaseID:	FBgn0003502	Length:	786	Species:	Drosophila melanogaster
Sequence 2:	NP_197392.2	Gene:	AT5G18910 / 832009	AraportID:	AT5G18910	Length:	511	Species:	Arabidopsis thaliana

Alignment Length:	364	Identity:	85/364 - (23%)
Similarity:	146/364 - (40%)	Gaps:	98/364 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   486 NYHRHNSGG----------------------------------LACRLKSSPCDRPVPPTAGLSH 516
            ::|.|:|||                                  |..|......|..||....|..
plant   103 HHHHHSSGGPNNGHWRRGFFRLLKKGSSAMPFNTFTPLKGVPKLTRRKSKRIRDNMVPVIPALDT 167

  Fly   517 D-------KW------EIHPMELMLMEE--LGSGQFGVVRRGKWRGSIDTAVKMMKEGTMSE--D 564
            |       .|      :|.........|  :|.|.:..|.:|:.......|:|.:..|:..|  .
plant   168 DHLFYFKPSWRNFSLRDIQTATNDYSRENLIGEGGYAEVYKGQMADGQIVAIKKLTRGSAEEMTM 232

  Fly   565 DFIEEAKVMTKLQHPNLVQLYGVCSKHRPIYIVTEYMKHGSLLNYLRRHEKTLIGNMGLLLDMCI 629
            |::.|..::..:.|||:.:|.|.|.: ..:::|.|...:|||.:.|...::.|  |..:...:.:
plant   233 DYLSELGIIVHVDHPNIAKLIGYCVE-GGMHLVLELSPNGSLASLLYEAKEKL--NWSMRYKVAM 294

  Fly   630 QVSKGMTYLE---RHNYIHRDLAARNCLVGSENVVKVADFGLARYVLDDQYTSSGGTKF--PIKW 689
            ..::|:.||.   :...||:|:.|.|.|:......:::|||||:: |.||:|....:|.  ...:
plant   295 GTAEGLYYLHEGCQRRIIHKDIKASNILLTQNFEAQISDFGLAKW-LPDQWTHHTVSKVEGTFGY 358

  Fly   690 APPEVLNYTRFSSKSDVWAYGVLMWEIFTCGKMPYGRLKNTEVVERVQRGIIL-EKP---KSCAK 750
            .|||...:.....|:||:|||||:.|:.|      ||    :.::..|..|:: .||   ::..|
plant   359 LPPEFFMHGIVDEKTDVYAYGVLLLELIT------GR----QALDSSQHSIVMWAKPLIKENKIK 413

  Fly   751 EI--------YDVMKLCWSHGPEERPAFRVLMDQLALVA 781
            ::        |||.:|                |:|..:|
plant   414 QLVDPILEDDYDVEEL----------------DRLVFIA 436

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Btk29A	NP_001097121.1	PH_Btk	44..222	CDD:269944
		SH3_Tec_like	346..399	CDD:212702
		SH2_Tec_family	403..505	CDD:198188	7/52 (13%)
		PTKc_Tec_like	521..778	CDD:173637	70/277 (25%)
		Pkinase_Tyr	526..777	CDD:285015	69/271 (25%)
AT5G18910	NP_197392.2	PKc_like	198..457	CDD:304357	70/269 (26%)
AT5G18910	NP_197392.2	TyrKc	198..457	CDD:197581	70/269 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	119	1.000	Inparanoid score	I1986
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050