DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Btk29A and PERK3

DIOPT Version :9

Sequence 1:	NP_001097121.1	Gene:	Btk29A / 34132	FlyBaseID:	FBgn0003502	Length:	786	Species:	Drosophila melanogaster
Sequence 2:	NP_001319631.1	Gene:	PERK3 / 822050	AraportID:	AT3G24540	Length:	479	Species:	Arabidopsis thaliana

Alignment Length:	243	Identity:	72/243 - (29%)
Similarity:	112/243 - (46%)	Gaps:	21/243 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   497 CRLKSSPCDRPVPPTAGLSHDKWEIHPMELMLME------------ELGSGQFGVVRRGKWRGSI 549
            |:.|....|:.:|...||   ...||.......|            .||.|.||.|.:|......
plant   145 CKKKRPRDDKALPAPIGL---VLGIHQSTFTYGELARATNKFSEANLLGEGGFGFVYKGILNNGN 206

  Fly   550 DTAVKMMKEGT-MSEDDFIEEAKVMTKLQHPNLVQLYGVCSKHRPIYIVTEYMKHGSLLNYLRRH 613
            :.|||.:|.|: ..|.:|..|..:::::.|.|||.|.|.|.......:|.|::.:.:|..:|...
plant   207 EVAVKQLKVGSAQGEKEFQAEVNIISQIHHRNLVSLVGYCIAGAQRLLVYEFVPNNTLEFHLHGK 271

  Fly   614 EKTLIGNMGLLLDMCIQVSKGMTYLERH---NYIHRDLAARNCLVGSENVVKVADFGLARYVLDD 675
            .:..: ...|.|.:.:..|||::||..:   ..||||:.|.|.|:..:...||||||||:..||.
plant   272 GRPTM-EWSLRLKIAVSSSKGLSYLHENCNPKIIHRDIKAANILIDFKFEAKVADFGLAKIALDT 335

  Fly   676 QYTSSGGTKFPIKWAPPEVLNYTRFSSKSDVWAYGVLMWEIFTCGKMP 723
            ....|........:..||.....:.:.||||:::||::.|:.| |:.|
plant   336 NTHVSTRVMGTFGYLAPEYAASGKLTEKSDVYSFGVVLLELIT-GRRP 382

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Btk29A	NP_001097121.1	PH_Btk	44..222	CDD:269944
		SH3_Tec_like	346..399	CDD:212702
		SH2_Tec_family	403..505	CDD:198188	2/7 (29%)
		PTKc_Tec_like	521..778	CDD:173637	66/219 (30%)
		Pkinase_Tyr	526..777	CDD:285015	64/214 (30%)
PERK3	NP_001319631.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	119	1.000	Inparanoid score	I1986
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050