Protein Alignment Btk and AT3G06640

DIOPT Version :10

• Sequence 1: NP_476745.1
• Gene: Btk / 34132
• FlyBaseID: FBgn0003502
• Length: 786
• Species: Drosophila melanogaster
• Sequence 2: NP_187316.2
• Gene: AT3G06640 / 819844
• AraportID: AT3G06640
• Length: 730
• Species: Arabidopsis thaliana
• Alignment Length: 675
• Identity: 171/675 - (25%)
• Similarity: 270/675 - (40%)
• Gaps: 179/675 - (26%)

  Fly   143 GSGVGIEGQQSGRAVPQYTLYVIANSEKERSEWIRAIRQVCEDSNTP--KSYRYHPGLWSGKKWS 205
            ||.:||....|.  |..|....|:.::.:.||        .|.|:||  .|:.:..||.:
plant   163 GSLIGIVSITSD--VAPYLNPTISLAKLKASE--------VETSSTPARNSFAFKLGLDT----- 212

  Fly   206 CCKGLSRTTFGCRAAAHWREA-NNNPSNGSSPAQNSTRSISPNSSTTNSQF-----SLQHNSSGS 264
              ||...:..|..:....:.| .:..|:.:|..:|..||..|...::.:.|     ...|:..|.
plant   213 --KGAVVSKLGLDSDQPIQVAIASKISDLASKVRNKVRSKMPAGDSSVTVFEGETGDSHHSDHGV 275

  Fly   265 LGGGVGGGLGGGGSLGLGGGGGGGGSCTPTSLQPQSSLTTFKQSPTLLNGNGTLLD---ANMPGG 326
            .|..:...:....|         .|:.||..        .|.|||.   |..|..|   ::.|..
plant   276 FGATLSDHMDDAAS---------SGASTPRG--------DFIQSPF---GVFTCNDDKFSSEPFI 320

  Fly   327 IPTPGTPNSKAKDNSHFVKLVVALYPFKAIEGGDLSLEKNAEYEVIDDSQEHWWKVKDALGNVGY 391
            ..:.|.|              :.|:..||.|                      |.||..|.
plant   321 DSSDGYP--------------ITLFTSKAEE----------------------WMVKKGLS---- 345

  Fly   392 IPSNYVKPKALLGLERYEWYVGDMSRQRAESLLKQGDKEGCFVVRKSSTKGLYTLSLHTKVPQSH 456
                            :.|              |..::||      |..|..|::....:..|..
plant   346 ----------------WPW--------------KGNEQEG------SRVKPTYSVWPCVQNEQKK 374

  Fly   457 VKHYHIKQNARCEYYLSEKHCCETIPDLINYHRHN-SGGL--ACRLKSSPCDRPVPPTAGLSHD- 517
            .|.:.|.:.:..:   |:.|..|:     |...:| :.||  :|...:|...|.:     :||.
plant   375 DKSHQINRYSGVK---SKSHASES-----NKPTNNKASGLRSSCINANSAISRGI-----ISHST 426

  Fly   518 -----------KWEIHPMELMLMEELGSGQFGVVRRGKWRGSIDTAVKMMKEGTMSED---DFIE 568
                       ::||...:|.:.|::|.|..|.|..|.|.|| |.|||::.:...||:   .|.:
plant   427 MNKVDTNSNCLEYEILWDDLTIGEQIGQGSCGTVYHGLWFGS-DVAVKLISKQEYSEEVIQSFRQ 490

  Fly   569 EAKVMTKLQHPNLVQLYGVCSKHRPIYIVTEYMKHGSLLNYLRRHEKTLIGNMGLL-----LDMC 628
            |..:|.:|:|||::...|..:..:.:.||:|::..|||...|:|       ||..|     ::|.
plant   491 EVSLMQRLRHPNVLLFMGAVTLPQGLCIVSEFLPRGSLFRLLQR-------NMSKLDWRRRINMA 548

  Fly   629 IQVSKGMTYLERHN--YIHRDLAARNCLVGSENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAP 691
            :.:::||.||.|.:  .|||||.:.|.||.....||||||||:|.......||..|...| :|..
plant   549 LDIARGMNYLHRCSPPIIHRDLKSSNLLVDKNLTVKVADFGLSRIKHHTYLTSKSGKGMP-QWMA 612

  Fly   692 PEVLNYTRFSSKSDVWAYGVLMWEIFTCGKMPYGRLKNTEVVERV----QRGIILEKPKSCAKEI 752
            ||||.......|||::::||::||:.| .|:|:..|.:.:|:..|    ||   ||.||....:.
plant   613 PEVLRNESADEKSDIYSFGVVLWELAT-EKIPWENLNSMQVIGAVGFMNQR---LEIPKDIDPDW 673

  Fly   753 YDVMKLCWSHGPEERPAFRVLMDQL 777
            ..:::.||....:.||.|:.||::|
plant   674 ISLIESCWHRDAKLRPTFQELMERL 698

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Btk	NP_476745.1	PH_Btk	44..222	CDD:269944	20/80 (25%)
		SH3_Tec_like	346..399	CDD:212702	8/52 (15%)
		SH2_Tec_family	403..505	CDD:198188	19/104 (18%)
		PTKc_Tec_like	521..778	CDD:173637	95/271 (35%)
AT3G06640	NP_187316.2	PAS	65..>175	CDD:441804	5/13 (38%)
		STKc_MAP3K-like	452..698	CDD:270901	91/258 (35%)