Protein Alignment Btk and AT3G06620

DIOPT Version :10

• Sequence 1: NP_476745.1
• Gene: Btk / 34132
• FlyBaseID: FBgn0003502
• Length: 786
• Species: Drosophila melanogaster
• Sequence 2: NP_187314.1
• Gene: AT3G06620 / 819841
• AraportID: AT3G06620
• Length: 773
• Species: Arabidopsis thaliana
• Alignment Length: 856
• Identity: 187/856 - (21%)
• Similarity: 295/856 - (34%)
• Gaps: 268/856 - (31%)

  Fly    14 SIKSSSSLRSSSKSFQAKMDLMSERLYDVVKSGSMVKRAQNKKRFTPVNYKH------------- 65
            |.:::|.||..|: .|..|.|.||     |..|     ..:..:||...|.:
plant    67 SFRNASPLRKESR-IQNSMRLRSE-----VGGG-----GPSAGKFTDKQYLNILQSMAQAVHAFD 120

  Fly    66 ------RWFELTKRTFSYFDVE--------------------NVERRRERGRIHLKGVRLVEEAT 104
                  .|..:.::.:.|...|                    |:.||..||.      ....|..
plant   121 LNMRIIFWNAMAEKVYGYSAAEALGENPINVIADDRDAAFAMNIARRCVRGE------SWTGEFP 179

  Fly   105 VSGEGGDPFAPDGYPFQVGYCEISASANSHQLENGNGGGSGVGIEGQQSGRAVPQYTLYVIANSE 169
            |..:.||.|              ||........:.:|...|:
plant   180 VKSKSGDRF--------------SAVTTCSPFYDDDGALMGI----------------------- 207

  Fly   170 KERSEWIRAIRQVCEDSNTPKSYRYHPGLWSGKKWSCCKGLSRTTFGCRAAAHWREANNNPSNGS 234
                        :|..|||..        :...:.|..|               .:|.......|
plant   208 ------------ICITSNTAP--------YLNPRISLAK---------------LKAQEEGETSS 237

  Fly   235 SPAQNSTRSISPNSSTTNSQFSLQHNSSGSLGGGVGGGLGGGGSLGLGGGGGGGGSCTPTSLQPQ 299
            .||:||..|            .|..:|.|::...:  ||.....:.:..........:..|.:.:
plant   238 IPARNSFAS------------KLGLDSRGAVISKL--GLDSDQPIQVAIASKISDLASKVSNKVR 288

  Fly   300 SSLTTFKQSPTLLNG-------------NGTLLDANMPGGIPTPGTPNSKAKDNSHFVKLVVALY 351
            |.:.....|.||..|             ..||:|...........||      ...|::....::
plant   289 SKMRAGDNSATLSEGGSGDSHQKDHNVFGATLVDHRDDAASSGASTP------RGDFIQSPFGVF 347

  Fly   352 ----------PFKAIEGGDLSLEKNAEYEVIDDSQEHW---------WKVKDALGNVGYIPSNYV 397
                      |||  :..|.|..|.|.::|:....|.|         ||..:..|:.|. |:|.|
plant   348 TCNDEKFVSKPFK--DSSDESDGKPAIHKVLTSKAEEWMVKKGLSWPWKGNEQEGSKGR-PTNSV 409

  Fly   398 KPKALLGLERYEWYVGDMSRQRAESLLKQGDKEGCFVVRKSSTKGLYTLSLHTKVPQSHVKHYHI 462
            .|          |...:..::|.                                       :.|
plant   410 WP----------WVQNEQKKERC---------------------------------------HQI 425

  Fly   463 KQNARCEYYLSEKHCCETIPDL-----------INYHRHNSGGLACRLKSSPCDRPVPPTAGLSH 516
            ..:|..:|   |.|..|:...:           ||.:..:|........||..::....:.||.:
plant   426 NPSAGVQY---ESHAFESNKPINNEASSLWSSPINANSTSSASSCGSTSSSVMNKVDTDSEGLEY 487

  Fly   517 D-KWEIHPMELMLMEELGSGQFGVVRRGKWRGSIDTAVKMMKEGTMSE---DDFIEEAKVMTKLQ 577
            : .|:    :|.:.|::|.|..|.|..|.|.|| |.|||:..:...|.   :.|.:|..:|.:|:
plant   488 EILWD----DLTIGEQVGQGSCGTVYHGLWFGS-DVAVKVFSKQEYSAEVIESFKQEVLLMKRLR 547

  Fly   578 HPNLVQLYGVCSKHRPIYIVTEYMKHGSLLNYLRRHEKTLIGNMGLLLDMCIQVSKGMTYLERHN 642
            |||::...|..:..:.:.||:|::..|||...|::....|  :....:.|.:.:::||.||...:
plant   548 HPNVLLFMGAVTSPQRLCIVSEFLPRGSLFRLLQKSTSKL--DWRRRIHMALDIARGMNYLHHCS 610

  Fly   643 --YIHRDLAARNCLVGSENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEVLNYTRFSSKSD 705
              .|||||.:.|.||.....||||||||:|...:...||..|...| :|..||||.......|||
plant   611 PPIIHRDLKSSNLLVDKNWTVKVADFGLSRIKHETYLTSKSGKGTP-QWMAPEVLRNESADEKSD 674

  Fly   706 VWAYGVLMWEIFTCGKMPYGRLKNTEVVERV----QRGIILEKPKSCAKEIYDVMKLCWSHGPEE 766
            ::::||::||:.| .|:|:..|.:.:|:..|    ||   ||.||........:|:.||....:.
plant   675 IYSFGVVLWELAT-EKIPWETLNSMQVIGAVGFMDQR---LEIPKDIDPRWISLMESCWHSDTKL 735

  Fly   767 RPAFRVLMDQL 777
            ||.|:.|||:|
plant   736 RPTFQELMDKL 746

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Btk	NP_476745.1	PH_Btk	44..222	CDD:269944	27/216 (13%)
		SH3_Tec_like	346..399	CDD:212702	17/71 (24%)
		SH2_Tec_family	403..505	CDD:198188	13/112 (12%)
		PTKc_Tec_like	521..778	CDD:173637	91/266 (34%)
AT3G06620	NP_187314.1	PAS	104..>210	CDD:441804	18/160 (11%)
		STKc_MAP3K-like	500..746	CDD:270901	88/253 (35%)