DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Btk29A and STY8

DIOPT Version :9

Sequence 1:	NP_001097121.1	Gene:	Btk29A / 34132	FlyBaseID:	FBgn0003502	Length:	786	Species:	Drosophila melanogaster
Sequence 2:	NP_179361.1	Gene:	STY8 / 816278	AraportID:	AT2G17700	Length:	546	Species:	Arabidopsis thaliana

Alignment Length:	303	Identity:	99/303 - (32%)
Similarity:	173/303 - (57%)	Gaps:	29/303 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   485 INYHRHNSGGLACRLKSSPCDRPVP-----PTAGLSHDKWEIHPMELMLMEELGSGQFGVVRRGK 544
            |::..|:        |||  :..:|     ||.|.  |:|||...:|.:.:::.||.:|.:.||.
plant   252 ISFFEHD--------KSS--NELIPACIEIPTDGT--DEWEIDVTQLKIEKKVASGSYGDLHRGT 304

  Fly   545 WRGSIDTAVKMMKEGTMSED---DFIEEAKVMTKLQHPNLVQLYGVCSKHRPIYIVTEYMKHGSL 606
            : .|.:.|:|.:|...::.:   :|.:|..:|.|::|.|:||..|.|::...:.||||:|..||:
plant   305 Y-CSQEVAIKFLKPDRVNNEMLREFSQEVFIMRKVRHKNVVQFLGACTRSPTLCIVTEFMARGSI 368

  Fly   607 LNYLRRHEKTLIGNMGLLLDMCIQVSKGMTYLERHNYIHRDLAARNCLVGSENVVKVADFGLARY 671
            .::|  |::.....:..||.:.:.|:|||:||.::|.|||||...|.|:....:|||||||:||.
plant   369 YDFL--HKQKCAFKLQTLLKVALDVAKGMSYLHQNNIIHRDLKTANLLMDEHGLVKVADFGVARV 431

  Fly   672 VLDD-QYTSSGGTKFPIKWAPPEVLNYTRFSSKSDVWAYGVLMWEIFTCGKMPYGRLKNTE-VVE 734
            .::. ..|:..||   .:|..|||:.:..::.|:||::|.:::||:.| |.:||..|...: .|.
plant   432 QIESGVMTAETGT---YRWMAPEVIEHKPYNHKADVFSYAIVLWELLT-GDIPYAFLTPLQAAVG 492

  Fly   735 RVQRGIILEKPKSCAKEIYDVMKLCWSHGPEERPAFRVLMDQL 777
            .||:|:..:.||....::..:::.||...||:||.|..:::.|
plant   493 VVQKGLRPKIPKKTHPKVKGLLERCWHQDPEQRPLFEEIIEML 535

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Btk29A	NP_001097121.1	PH_Btk	44..222	CDD:269944
		SH3_Tec_like	346..399	CDD:212702
		SH2_Tec_family	403..505	CDD:198188	5/19 (26%)
		PTKc_Tec_like	521..778	CDD:173637	87/262 (33%)
		Pkinase_Tyr	526..777	CDD:285015	85/255 (33%)
STY8	NP_179361.1	ACT_TyrKc	172..239	CDD:153200
		Pkinase_Tyr	286..535	CDD:285015	85/255 (33%)
		STKc_MAP3K-like	292..535	CDD:270901	84/249 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	165	1.000	Domainoid score	I1208
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910