DRSC/TRiP Functional Genomics Resources

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Protein Alignment Btk and YES1

DIOPT Version :10

Sequence 1:NP_476745.1 Gene:Btk / 34132 FlyBaseID:FBgn0003502 Length:786 Species:Drosophila melanogaster
Sequence 2:NP_005424.1 Gene:YES1 / 7525 HGNCID:12841 Length:543 Species:Homo sapiens


Alignment Length:50 Identity:14/50 - (28%)
Similarity:20/50 - (40%) Gaps:16/50 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 QNTNMSNM---------YNGTTEPLLSLPNTQSLIEPQTPTIPEIYFFIL 42
            ||:...|:         .:|...||.:.|       |.||:.|:..||.|
Human   514 QNSERRNLKLLDTRKLSRDGAGSPLRTSP-------PSTPSSPDDTFFNL 556

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
BtkNP_476745.1 PH_Btk 44..222 CDD:269944
SH3_Tec_like 346..399 CDD:212702
SH2_Tec_family 403..505 CDD:198188
PTKc_Tec_like 521..778 CDD:173637
YES1NP_005424.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..45
SH3_Yes 94..151 CDD:212940
SH2_Src_family 154..253 CDD:199827
PTKc_Yes 264..542 CDD:270654 6/27 (22%)
Blue background indicates that the domain is not in the aligned region.

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