| Sequence 1: | NP_001097121.1 | Gene: | Btk29A / 34132 | FlyBaseID: | FBgn0003502 | Length: | 786 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001372133.1 | Gene: | TYK2 / 7297 | HGNCID: | 12440 | Length: | 1257 | Species: | Homo sapiens |
| Alignment Length: | 593 | Identity: | 159/593 - (26%) |
|---|---|---|---|
| Similarity: | 234/593 - (39%) | Gaps: | 175/593 - (29%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 297 QPQSSLTTFKQSPTLLNGN---GTLLDANMPGGIPTPGTPNSKAKDNSHFVKLV----------- 347
Fly 348 ---VALYPFKAIE---GGDLSLEKNAE--------YEVIDDSQ--------------EHWWKVKD 384
Fly 385 ALGNVGYIPSNYVKPKALLGLERYEWYVGDMSRQRAESLLKQGDKEGCFVVRKSSTKG------- 442
Fly 443 --------LYTLSLHTKVPQSHVK-HYHIKQNARCEYYLSEKHC---------CET--------- 480
Fly 481 ---IPDLINYHRHNSGGLACRLKSSPCDRPVPPTAGLSHDKWEIHPMELMLMEELGSGQFGVVRR 542
Fly 543 GKWRGSID-----TAVKMMKE--GTMSEDDFIEEAKVMTKLQHPNLVQLYGVCSK--HRPIYIVT 598
Fly 599 EYMKHGSLLNYLRRHEKTLIGNMGLLLDMCIQVSKGMTYLERHNYIHRDLAARNCLVGSENVVKV 663
Fly 664 ADFGLARYVLD--DQYTSSGGTKFPIKWAPPEVLNYTRFSSKSDVWAYGVLMWEIFT-C------ 719
Fly 720 ------------GKMPYGRLKNTEVVERVQRGIILEKPKSCAKEIYDVMKLCWSHGPEERPAFRV 772
Fly 773 LMDQLALV 780 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Btk29A | NP_001097121.1 | PH_Btk | 44..222 | CDD:269944 | |
| SH3_Tec_like | 346..399 | CDD:212702 | 18/91 (20%) | ||
| SH2_Tec_family | 403..505 | CDD:198188 | 27/138 (20%) | ||
| PTKc_Tec_like | 521..778 | CDD:173637 | 96/286 (34%) | ||
| Pkinase_Tyr | 526..777 | CDD:285015 | 95/280 (34%) | ||
| TYK2 | NP_001372133.1 | FERM_F1 | 28..125 | CDD:408179 | |
| FERM_F2 | 143..266 | CDD:408177 | |||
| Jak1_Phl | 285..432 | CDD:407742 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 335..366 | ||||
| SH2 | 437..534 | CDD:417686 | |||
| PKc_like | 589..937 | CDD:419665 | 51/266 (19%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 610..629 | ||||
| PTKc_Tyk2_rpt2 | 962..1244 | CDD:270664 | 98/290 (34%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E2759_KOG0197 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||