DRSC/TRiP Functional Genomics Resources

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Protein Alignment Btk29A and Ack

DIOPT Version :9

Sequence 1:NP_001097121.1 Gene:Btk29A / 34132 FlyBaseID:FBgn0003502 Length:786 Species:Drosophila melanogaster
Sequence 2:NP_647859.1 Gene:Ack / 38489 FlyBaseID:FBgn0028484 Length:1073 Species:Drosophila melanogaster


Alignment Length:274 Identity:108/274 - (39%)
Similarity:157/274 - (57%) Gaps:23/274 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly   521 IHPMELMLMEELGSGQFGVVRRGKWRGS-----IDTAVKMMKEGTMSE----DDFIEEAKVMTKL 576
            ||..::.:..:||.|.|||||||:|..|     |..|||::|...:::    |||..|.:.|..|
  Fly   118 IHEKDITMGLKLGDGSFGVVRRGEWSASPAGKVIPVAVKVLKSDNLTQPGIIDDFFREVQAMHAL 182

  Fly   577 QHPNLVQLYGVCSKHRPIYIVTEYMKHGSLLNYLR---RHEK-TLIGNMGLLLDMCIQVSKGMTY 637
            .|.|||:||||... :|:.::||..:.||||:.||   ||.. |:|.|..      :|:..||.|
  Fly   183 DHANLVRLYGVVLS-QPMMMITELAERGSLLDTLRKQCRHTSLTIIWNWS------VQIVTGMAY 240

  Fly   638 LERHNYIHRDLAARNCLVGSENVVKVADFGLARYV--LDDQYTSSGGTKFPIKWAPPEVLNYTRF 700
            ||:..::|||||.||.|:.:.|.:|:.||||.|.:  .||.|..|...|.|..|..||.|.:.:|
  Fly   241 LEQKRFLHRDLACRNVLLAAGNKIKIGDFGLMRALPQEDDCYVMSEHKKVPFPWCAPESLRFRQF 305

  Fly   701 SSKSDVWAYGVLMWEIFTCGKMPYGRLKNTEVVERVQR-GIILEKPKSCAKEIYDVMKLCWSHGP 764
            |..||.|.:||.:||:|:.|:.|:..|..::::.::.| |..|.:|.:|..::|.:|..||...|
  Fly   306 SHASDTWMFGVTLWEMFSFGEDPWVGLNGSQILRKIDREGERLHQPDACPPDVYAMMLQCWDKTP 370

  Fly   765 EERPAFRVLMDQLA 778
            .|||.|..|.:.||
  Fly   371 AERPTFAALKEYLA 384

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Btk29ANP_001097121.1 PH_Btk 44..222 CDD:269944
SH3_Tec_like 346..399 CDD:212702
SH2_Tec_family 403..505 CDD:198188
PTKc_Tec_like 521..778 CDD:173637 106/272 (39%)
Pkinase_Tyr 526..777 CDD:285015 104/266 (39%)
AckNP_647859.1 SAM_TNK-like 14..75 CDD:188938
PTKc_Ack_like 128..385 CDD:270636 106/264 (40%)
UBA_TNK1 1031..1070 CDD:270513
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45468345
Domainoid 1 1.000 165 1.000 Domainoid score I1208
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR24418
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
43.940

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