| Sequence 1: | NP_001097121.1 | Gene: | Btk29A / 34132 | FlyBaseID: | FBgn0003502 | Length: | 786 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_000206.2 | Gene: | JAK3 / 3718 | HGNCID: | 6193 | Length: | 1124 | Species: | Homo sapiens |
| Alignment Length: | 440 | Identity: | 130/440 - (29%) |
|---|---|---|---|
| Similarity: | 196/440 - (44%) | Gaps: | 71/440 - (16%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 397 VKPKALLGLE----RYEWYVGDMSRQRAESLLKQGDKEGCFVVRKSSTKGLYTLSLHTKVPQSHV 457
Fly 458 KHYHIKQNARC----EYYLSEKHCC-----------ETIPDL-----INYHRHNSGGLACRLKSS 502
Fly 503 PCDRPVPPTAGL--------SHDKWEIHPMELMLMEELGSGQFGVVR------RGKWRGSIDTAV 553
Fly 554 KMMKEGTMSEDDFIEEAKVMTKLQHPNLVQLYGVC--SKHRPIYIVTEYMKHGSLLNYLRRHEKT 616
Fly 617 LIGNMGLLLDMCIQVSKGMTYLERHNYIHRDLAARNCLVGSENVVKVADFGLARYV-LD-DQYTS 679
Fly 680 SGGTKFPIKWAPPEVLNYTRFSSKSDVWAYGVLMWEIFT-CGK-----MPYGRLKNTE------- 731
Fly 732 -VVERVQRGIILEKPKSCAKEIYDVMKLCWSHGPEERPAFRVLMDQLALV 780 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Btk29A | NP_001097121.1 | PH_Btk | 44..222 | CDD:269944 | |
| SH3_Tec_like | 346..399 | CDD:212702 | 1/1 (100%) | ||
| SH2_Tec_family | 403..505 | CDD:198188 | 26/125 (21%) | ||
| PTKc_Tec_like | 521..778 | CDD:173637 | 96/280 (34%) | ||
| Pkinase_Tyr | 526..777 | CDD:285015 | 95/274 (35%) | ||
| JAK3 | NP_000206.2 | Interaction with cytokine/interferon/growth hormone receptors. /evidence=ECO:0000250 | 1..223 | ||
| B41 | 39..>200 | CDD:214604 | |||
| PH-like | 250..362 | CDD:302622 | |||
| SH2_Jak3 | 362..458 | CDD:198243 | |||
| PTK_Jak3_rpt1 | 521..778 | CDD:271110 | 24/106 (23%) | ||
| Pkinase_Tyr | 521..777 | CDD:285015 | 23/105 (22%) | ||
| PTKc_Jak3_rpt2 | 817..1099 | CDD:270665 | 97/284 (34%) | ||
| Pkinase_Tyr | 822..1095 | CDD:285015 | 95/274 (35%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E2759_KOG0197 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||