| Sequence 1: | NP_001097121.1 | Gene: | Btk29A / 34132 | FlyBaseID: | FBgn0003502 | Length: | 786 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001309123.1 | Gene: | JAK2 / 3717 | HGNCID: | 6192 | Length: | 1132 | Species: | Homo sapiens |
| Alignment Length: | 290 | Identity: | 98/290 - (33%) |
|---|---|---|---|
| Similarity: | 154/290 - (53%) | Gaps: | 32/290 - (11%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 517 DKWEIHPMELMLMEELGSGQFGVVRRGKW------RGSIDTAVKMMKEGTMSE-DDFIEEAKVMT 574
Fly 575 KLQHPNLVQLYGVC--SKHRPIYIVTEYMKHGSLLNYLRRHEKTLIGNMGLLLDMCIQVSKGMTY 637
Fly 638 LERHNYIHRDLAARNCLVGSENVVKVADFGLARYVLDDQ--YTSSGGTKFPIKWAPPEVLNYTRF 700
Fly 701 SSKSDVWAYGVLMWEIFT---------------CGKMPYGRLKNTEVVERVQRGIILEKPKSCAK 750
Fly 751 EIYDVMKLCWSHGPEERPAFRVL---MDQL 777 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Btk29A | NP_001097121.1 | PH_Btk | 44..222 | CDD:269944 | |
| SH3_Tec_like | 346..399 | CDD:212702 | |||
| SH2_Tec_family | 403..505 | CDD:198188 | |||
| PTKc_Tec_like | 521..778 | CDD:173637 | 97/286 (34%) | ||
| Pkinase_Tyr | 526..777 | CDD:285015 | 96/279 (34%) | ||
| JAK2 | NP_001309123.1 | Interaction with cytokine/interferon/growth hormone receptors. /evidence=ECO:0000250 | 1..239 | ||
| B41 | 38..270 | CDD:214604 | |||
| FERM_C_JAK2 | 266..386 | CDD:270141 | |||
| SH2_Jak2 | 386..482 | CDD:198242 | |||
| PTK_Jak2_rpt1 | 545..806 | CDD:270663 | |||
| Pkinase_Tyr | 545..805 | CDD:285015 | |||
| PTKc_Jak2_rpt2 | 844..1127 | CDD:271107 | 97/286 (34%) | ||
| TyrKc | 849..1119 | CDD:197581 | 94/272 (35%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E2759_KOG0197 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||