Protein Alignment Btk and CG3277

DIOPT Version :10

• Sequence 1: NP_476745.1
• Gene: Btk / 34132
• FlyBaseID: FBgn0003502
• Length: 786
• Species: Drosophila melanogaster
• Sequence 2: NP_608762.3
• Gene: CG3277 / 33543
• FlyBaseID: FBgn0031518
• Length: 789
• Species: Drosophila melanogaster
• Alignment Length: 355
• Identity: 98/355 - (27%)
• Similarity: 155/355 - (43%)
• Gaps: 93/355 - (26%)

  Fly   513 GLSHDKWEIHPMELMLMEELGSGQFGVVRRG------KWRGSIDTAVKMMKEGTMSED--DFIEE 569
            ||: |.:|:....:.:...||.|.||.|...      :.||:...|||.:|....:::  :::.|
  Fly   414 GLA-DIFEVPHSAIQIGRMLGEGAFGQVHEATAINLRRMRGTTIVAVKQLKPNPKADEVAEYLAE 477

  Fly   570 AKVMTKL-QHPNLVQLYGVCSKHRPIYIVTEYMKHGSLLNYLR--RHEKTLIGNMGLLLDMC--- 628
            .:::..: .|.|:|...|.|:...|..::.||:..|:||:|||  |.|.:.:.|.......|
  Fly   478 IEMLKGVGTHHNVVSFLGCCTIKPPYLMIMEYVNKGNLLSYLRTVRKEASKLRNRNANYTSCRPI 542

  Fly   629 ----------------------------------------------------------------- 628
                                                                             
  Fly   543 MTRTNSTSSPKSQSVNYIELKASSQTIEMPQEDSTAHMNGIRQPHPSFAETTYTIVEDEDAFEYI 607

  Fly   629 ----------IQVSKGMTYLERHNYIHRDLAARNCLVGSENVVKVADFGLARYVLDDQYTSSGGT 683
                      :|::.||.:||.....||||||||.|:.|...:|::||||:|:.:   ||::...
  Fly   608 LDNKELHNFALQIANGMRFLEEQEITHRDLAARNVLIDSNKTLKISDFGLSRHGI---YTNTRTR 669

  Fly   684 KFPIKWAPPEVLNYTRFSSKSDVWAYGVLMWEIFTCGKMPYGRLKNTEVVERVQRGIILEKPKSC 748
            |.|::|...|.:....:|||||:|||||::|||.|.|..||..:.|.|::..:..|..||:|:.|
  Fly   670 KLPLRWLSIEAIRENVYSSKSDIWAYGVVLWEIGTLGASPYPTISNDELIPFLMAGNRLERPEIC 734

  Fly   749 AKEIYDVMKLCWSHGPEERPAFRVLMDQLA 778
            ..::|.:|..||...|||||.|..|...|:
  Fly   735 TPQVYTIMLQCWLEEPEERPTFDALYKVLS 764

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Btk	NP_476745.1	PH_Btk	44..222	CDD:269944
		SH3_Tec_like	346..399	CDD:212702
		SH2_Tec_family	403..505	CDD:198188
		PTKc_Tec_like	521..778	CDD:173637	93/345 (27%)
CG3277	NP_608762.3	PTKc	430..763	CDD:270623	93/335 (28%)