DRSC/TRiP Functional Genomics Resources

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Protein Alignment Btk29A and sel-15

DIOPT Version :9

Sequence 1:NP_001097121.1 Gene:Btk29A / 34132 FlyBaseID:FBgn0003502 Length:786 Species:Drosophila melanogaster
Sequence 2:NP_001366799.1 Gene:sel-15 / 175225 WormBaseID:WBGene00016030 Length:847 Species:Caenorhabditis elegans


Alignment Length:344 Identity:99/344 - (28%)
Similarity:160/344 - (46%) Gaps:52/344 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly   484 LINYHRHNSGGLACRLKSS------PCDRPVPPTAGLSHDKWEIHPM-------------ELMLM 529
            |.:|......|..|...||      |...|:.....|:.||.::..:             |:...
 Worm   455 LKHY
AARTVEGDVCSEYSSGESSYTPLPSPMGRLTSLTRDKADLLQLRSALPAPFHLCLAEIEFQ 519

  Fly   530 EELGSGQFGVVRRGKWRGSIDTAVK---MMKEGTMSEDDFI-EEAKVMTKLQHPNLVQLYGVCSK 590
            |.:|||.||.|.:|.:||.: .|||   .|..|..||.|.: .|..::::|.|||:|...|. |.
 Worm   520 ESIGSGSFGKVYKGTYRGKL-VAVKRYRAMAFGCKSETDMLCREVSILSRLAHPNVVAFVGT-SL 582

  Fly   591 HRP--IYIVTEYMKHGSLLNYLRRHEKTLIGNMGLLLDMCIQVSKGMTYLER---HNYIHRDLAA 650
            ..|  ..|:||::::|||...|  ||:..:.:....|.:.:.|::||.||..   ...|||||.:
 Worm   583 DDPSQFAIITEFVENGSLFRLL--HEEKRVMDPAFRLRISLDVARGMRYLHESAAKPVIHRDLNS 645

  Fly   651 RNCLVGSENVVKVADFGLARYVL---DDQYTSSGGTKFPIKWAPPEVLNYT-RFSSKSDVWAYGV 711
            .|.|:.::....|||||.:|:|.   |:..|...|.   ::|..|||.:.: ::..|.||:::.:
 Worm   646 HNILIHADGRSVVADFGESRFVCQREDENLTKQPGN---LRWMAPEVFSQSGKYDRKVDVFSFAL 707

  Fly   712 LMWEIFTCGKMPYGRLK----NTEVVERVQRGIILEKPKS-CAKEIYDVMKLCWSHGPEERPAFR 771
            ::|||.| .::|:..||    ..|:..:..|..:..:|.: ....|..::...|......||.| 
 Worm   708 VIWEIHT-AELPFSHLKPAAAAAEMTYKRGRPTLPNQPTAQFPAHILSLIPQAWHPESSSRPDF- 770

  Fly   772 VLMDQLAL----VAQTLTD 786
              ::.:||    |..|.||
 Worm   771 --VEIVALLEPHVESTHTD 787

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Btk29ANP_001097121.1 PH_Btk 44..222 CDD:269944
SH3_Tec_like 346..399 CDD:212702
SH2_Tec_family 403..505 CDD:198188 7/26 (27%)
PTKc_Tec_like 521..778 CDD:173637 82/287 (29%)
Pkinase_Tyr 526..777 CDD:285015 81/268 (30%)
sel-15NP_001366799.1 ANKYR 3..217 CDD:223738
ANK repeat 115..147 CDD:293786
PHA03095 128..>388 CDD:222980
ANK repeat 153..180 CDD:293786
ANK repeat 182..213 CDD:293786
ANK repeat 215..246 CDD:293786
ANK repeat 285..318 CDD:293786
ANK repeat 320..353 CDD:293786
ANKYR <323..458 CDD:223738 1/2 (50%)
ANK repeat 355..380 CDD:293786
PKc_TNNI3K 522..780 CDD:270966 82/268 (31%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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