DRSC/TRiP Functional Genomics Resources

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Protein Alignment Btk29A and Matk

DIOPT Version :9

Sequence 1:NP_001097121.1 Gene:Btk29A / 34132 FlyBaseID:FBgn0003502 Length:786 Species:Drosophila melanogaster
Sequence 2:XP_006513357.1 Gene:Matk / 17179 MGIID:99259 Length:506 Species:Mus musculus


Alignment Length:476 Identity:154/476 - (32%)
Similarity:238/476 - (50%) Gaps:56/476 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly   321 ANMPGGIPTPGTPNSKAKDNSHFVKLVVALYPFKAIEGGDLSLEKNAEYEVIDDSQE-HWWKVK- 383
            |.||.....|||......:||.         |    :.|:|:..|.....:::..:: .|::.| 
Mouse    39 ARMPTQRWAPGTQCMTKCENSR---------P----KPGELAFRKGDMVTILEACEDKSWYRAKH 90

  Fly   384 DALGNVGYIPSNYVKPKALLG----LERYEWYVGDMSRQRAESLLKQGDKEGCFVVRKSST-KGL 443
            ...|..|.:.:..::.:..|.    |....|:.|.:|.|.|...| |..::|.|:||:|:. .|.
Mouse    91 HGSGQEGLLAAAALRQREALSTDPKLSLMPWFHGKISGQEAIQQL-QPPEDGLFLVRESARHPGD 154

  Fly   444 YTLSLHTKVPQSHVKHYHIKQNARCEYYLSEKHCCETIPDLINYHRHNSGGLACRLKSSPCDRPV 508
            |.|.:..   ...|.||.:..... ...:.|..|...:.|::.::..:.|.:        |.:.|
Mouse   155 YVLCVSF---GRDVIHYRVLHRDG-HLTIDEAVCFCNLMDMVEHYTKDKGAI--------CTKLV 207

  Fly   509 PP---------TAGLSHDKWEIHPMELMLMEELGSGQFGVVRRGKWRGSIDTAVKMMKEGTMSED 564
            .|         ...|:...|.:....|.|..::|.|:||.|.:|::.|. ..|||.:| ..::..
Mouse   208 KPRRKQGAKSAEEELAKAGWLLDLQHLTLGAQIGEGEFGAVLQGEYLGQ-KVAVKNIK-CDVTAQ 270

  Fly   565 DFIEEAKVMTKLQHPNLVQLYGVCSKHRPIYIVTEYMKHGSLLNYLRRHEKTLIGNMGLLLDMCI 629
            .|::|..|||||||.|||:|.||. .|..:|||.|::..|:|:|:||...:.|: :...||...:
Mouse   271 AFLDETAVMTKLQHRNLVRLLGVI-LHHGLYIVMEHVSKGNLVNFLRTRGRALV-STSQLLQFAL 333

  Fly   630 QVSKGMTYLERHNYIHRDLAARNCLVGSENVVKVADFGLA---RYVLDDQYTSSGGTKFPIKWAP 691
            .|::||.|||....:||||||||.||..:.|.||:|||||   |..||       .::.|:||..
Mouse   334 HVAEGMEYLESKKLVHRDLAARNILVSEDLVAKVSDFGLAKAERKGLD-------SSRLPVKWTA 391

  Fly   692 PEVLNYTRFSSKSDVWAYGVLMWEIFTCGKMPYGRLKNTEVVERVQRGIILEKPKSCAKEIYDVM 756
            ||.|...|||||||||::|||:||:|:.|:.||.::...||.|.|::|..:|.|..|...::.:|
Mouse   392 PEALKNGRFSSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVSEAVEKGYRMEPPDGCPGSVHTLM 456

  Fly   757 KLCWSHGPEERPAFRVLMDQL 777
            ..||...|..||.||.::::|
Mouse   457 GSCWEAEPARRPPFRKIVEKL 477

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Btk29ANP_001097121.1 PH_Btk 44..222 CDD:269944
SH3_Tec_like 346..399 CDD:212702 8/54 (15%)
SH2_Tec_family 403..505 CDD:198188 24/106 (23%)
PTKc_Tec_like 521..778 CDD:173637 109/260 (42%)
Pkinase_Tyr 526..777 CDD:285015 108/253 (43%)
MatkXP_006513357.1 SH3 49..107 CDD:388381 12/70 (17%)
SH2_csk_like 117..214 CDD:198190 25/109 (23%)
PKc_like 227..480 CDD:389743 110/262 (42%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0197
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000006
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.810

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