| Sequence 1: | NP_001097121.1 | Gene: | Btk29A / 34132 | FlyBaseID: | FBgn0003502 | Length: | 786 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001268894.1 | Gene: | Itk / 16428 | MGIID: | 96621 | Length: | 625 | Species: | Mus musculus |
| Alignment Length: | 753 | Identity: | 280/753 - (37%) |
|---|---|---|---|
| Similarity: | 397/753 - (52%) | Gaps: | 159/753 - (21%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 48 MVKRAQNKKRFTPVNYKHRWFELTKRTFSYFDVENVERRRERGRIHLKGVRLVEEATVSGEGGDP 112
Fly 113 FAPDGYPFQ-VGYCEISASANSHQLENGNGGGSGVGIEGQQSGRAVPQYTLYVIANSEKERSEWI 176
Fly 177 RAIRQVCEDSNTPKSYRYHPGLWSGKKWSCCKGLSRTTFGCRAAAHWREANNNPSNGSSPAQNST 241
Fly 242 RSISPNSSTTNSQFSLQHNSSGSLGGGVGGGLGGGGSLGLGGGGGGGGSCTPTSLQPQSSLTTFK 306
Fly 307 QSPTLLNGNGTLLDANMPGGIPTPGTPNSKAKDNSHFVK-----LVVALYPFKAIEGGDLSLEKN 366
Fly 367 AEYEVIDDSQEHWWKVKDALGNVGYIPSNYVKPKALLGLERYEWYVGDMSRQRAESLLKQGDKEG 431
Fly 432 CFVVRKSSTKGLYTLSLHTKVPQSH---VKHYHIKQ--NARCEYYLSEKHCCETIPDLINYHRHN 491
Fly 492 SGGLACRLKSSPCD--RPVPPTAGLSHDKWEIHPMELMLMEELGSGQFGVVRRGKWRGSIDTAVK 554
Fly 555 MMKEGTMSEDDFIEEAKVMTKLQHPNLVQLYGVCSKHRPIYIVTEYMKHGSLLNYLRRHE----- 614
Fly 615 KTLIGNMGLLLDMCIQVSKGMTYLERHNYIHRDLAARNCLVGSENVVKVADFGLARYVLDDQYTS 679
Fly 680 SGGTKFPIKWAPPEVLNYTRFSSKSDVWAYGVLMWEIFTCGKMPYGRLKNTEVVERVQRGIILEK 744
Fly 745 PKSCAKEIYDVMKLCWSHGPEERPAFRVLMDQLALVAQ 782 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Btk29A | NP_001097121.1 | PH_Btk | 44..222 | CDD:269944 | 47/174 (27%) |
| SH3_Tec_like | 346..399 | CDD:212702 | 22/52 (42%) | ||
| SH2_Tec_family | 403..505 | CDD:198188 | 49/106 (46%) | ||
| PTKc_Tec_like | 521..778 | CDD:173637 | 142/261 (54%) | ||
| Pkinase_Tyr | 526..777 | CDD:285015 | 138/255 (54%) | ||
| Itk | NP_001268894.1 | PH | 5..117 | CDD:278594 | 35/136 (26%) |
| PH_Btk | 7..154 | CDD:269944 | 47/188 (25%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 153..174 | 8/108 (7%) | |||
| SH3_ITK | 180..235 | CDD:212841 | 22/54 (41%) | ||
| SH2_Tec_Itk | 238..345 | CDD:198259 | 49/106 (46%) | ||
| PTKc_Itk | 363..618 | CDD:133243 | 142/261 (54%) | ||
| Pkinase_Tyr | 368..617 | CDD:285015 | 138/255 (54%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 316 | 1.000 | Domainoid score | I1270 |
| eggNOG | 1 | 0.900 | - | - | E2759_KOG0197 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 559 | 1.000 | Inparanoid score | I1093 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG52659 | |
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 1 | 1.000 | - | - | FOG0000006 | |
| OrthoInspector | 1 | 1.000 | - | - | otm44145 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_102306 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR24418 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 1 | 1.000 | - | - | X592 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| 11 | 10.830 | |||||