Sequence 1: | NP_001097121.1 | Gene: | Btk29A / 34132 | FlyBaseID: | FBgn0003502 | Length: | 786 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_001120662.1 | Gene: | CSK / 1445 | HGNCID: | 2444 | Length: | 450 | Species: | Homo sapiens |
Alignment Length: | 441 | Identity: | 166/441 - (37%) |
---|---|---|---|
Similarity: | 252/441 - (57%) | Gaps: | 26/441 - (5%) |
- Green bases have known domain annotations that are detailed below.
Fly 348 VALYPFKAIEGGDLSLEKNAEYEVIDDSQE-HWWKVKDALGNVGYIPSNYVKP----KALLGLER 407
Fly 408 YEWYVGDMSRQRAESLLKQGDKEGCFVVRKSST-KGLYTLSLHTKVPQSHVKHYHIKQNARCEYY 471
Fly 472 LSEKHCCETIPDLINYHRHNSGGLACRL-KSSPCDRPVPPTAGLSHDKWEIHPMELMLMEELGSG 535
Fly 536 QFGVVRRGKWRGSIDTAVKMMKEGTMSEDDFIEEAKVMTKLQHPNLVQLYGVCSKHR-PIYIVTE 599
Fly 600 YMKHGSLLNYLRRHEKTLIGNMGLL---LDMCIQVSKGMTYLERHNYIHRDLAARNCLVGSENVV 661
Fly 662 KVADFGLARYVLDDQYTSSGGTKFPIKWAPPEVLNYTRFSSKSDVWAYGVLMWEIFTCGKMPYGR 726
Fly 727 LKNTEVVERVQRGIILEKPKSCAKEIYDVMKLCWSHGPEERPAFRVLMDQL 777 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
Btk29A | NP_001097121.1 | PH_Btk | 44..222 | CDD:269944 | |
SH3_Tec_like | 346..399 | CDD:212702 | 16/51 (31%) | ||
SH2_Tec_family | 403..505 | CDD:198188 | 30/103 (29%) | ||
PTKc_Tec_like | 521..778 | CDD:173637 | 116/261 (44%) | ||
Pkinase_Tyr | 526..777 | CDD:285015 | 113/254 (44%) | ||
CSK | NP_001120662.1 | Interaction with PTPN22. /evidence=ECO:0000250|UniProtKB:P41241 | 9..70 | 16/54 (30%) | |
SH3_CSK | 11..67 | CDD:212703 | 16/51 (31%) | ||
SH2_csk_like | 78..175 | CDD:198190 | 29/101 (29%) | ||
PTKc_Csk | 188..443 | CDD:133213 | 117/263 (44%) | ||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E2759_KOG0197 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 1 | 1.000 | - | - | FOG0000006 | |
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
3 | 2.810 |