Protein Alignment Btk and l(3)05822

DIOPT Version :10

• Sequence 1: NP_476745.1
• Gene: Btk / 34132
• FlyBaseID: FBgn0003502
• Length: 786
• Species: Drosophila melanogaster
• Sequence 2: XP_322013.6
• Gene: l(3)05822 / 1282018
• VectorBaseID: AGAMI1_009579
• Length: 606
• Species: Anopheles gambiae
• Alignment Length: 323
• Identity: 68/323 - (21%)
• Similarity: 108/323 - (33%)
• Gaps: 91/323 - (28%)

  Fly   128 SASANSHQLENGNGGGSGVGIEGQQSGRA--VPQYTLY----------------VIANSEKERSE 174
            |:|.....|:...||.:.    |..||||  .|...:|                .:.||:.::|:
Mosquito   282 SSSVPWGDLDPFEGGSTA----GTSSGRAKTAPPPVIYGTIPLASSSSTAQIRTPLINSKLQKSD 342

  Fly   175 WIRAIRQVCE-DSNTPKSYRYHPGLWSGKKWSCCKGLSRTTFGCRAAAHWREANNNPSNGSSPAQ 238
            ::..:   |. .|..|:    ||            .:|..|.          .....|:.||.:|
Mosquito   343 FVDPL---CNGQSVLPR----HP------------TMSMPTI----------IKPPTSSNSSDSQ 378

  Fly   239 NSTRSISPNSSTTNSQFSLQHNSSGSLGGGVGGGLGGGGSLGLGGGGGGGGSCTPTSLQPQSSLT 303
            .||    |:.|.      |..:::.|           |.|..:......||......::..|
Mosquito   379 KST----PSHSV------LPRHAAAS-----------GSSKQMAPIPPAGGQDPYAGMEADS--- 419

  Fly   304 TFKQSPTLLNGNGTLLDANMPGGIPTPGTPNSKAKDNSHFVKLVVALYPFKAIEGGDLSLEKNAE 368
                ...:|....:|....||...|.|..|.::|.....:   .:|||.|:.....|||.:.|.:
Mosquito   420 ----CSDVLGAFDSLPSQPMPSIPPPPPPPATEAYAEDPY---GIALYDFQGEADEDLSFKANEK 477

  Fly   369 YEVIDDSQEHWWKVKDALGNVGYIPSNYVKPKALLGLERYEWYVGDMSRQRAESLLKQGDKEG 431
            ..::....|.|:..:|..|..|..|.|||:.|..|        |.:.|.:....|:......|
Mosquito   478 IYLLKRLTEEWYMGRDKRGLEGMFPVNYVEVKVPL--------VDEQSNESVTRLIPATSDNG 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Btk	NP_476745.1	PH_Btk	44..222	CDD:269944	22/112 (20%)
		SH3_Tec_like	346..399	CDD:212702	17/52 (33%)
		SH2_Tec_family	403..505	CDD:198188	5/29 (17%)
		PTKc_Tec_like	521..778	CDD:173637
l(3)05822	XP_322013.6	None