| Sequence 1: | NP_001097121.1 | Gene: | Btk29A / 34132 | FlyBaseID: | FBgn0003502 | Length: | 786 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_038510.2 | Gene: | Btk / 12229 | MGIID: | 88216 | Length: | 659 | Species: | Mus musculus |
| Alignment Length: | 768 | Identity: | 299/768 - (38%) |
|---|---|---|---|
| Similarity: | 408/768 - (53%) | Gaps: | 152/768 - (19%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 42 VVKSGSMVKRAQNKKRFTPVNYKHRWFELTKRTFSY--FDVENVERRRERGRIHLKGVRLVEEAT 104
Fly 105 VSGEGGDPFAPD----------------------GYPFQVGYCEISASANSHQLENGNGGGSGVG 147
Fly 148 IEGQQSGRAVPQYTLYVIANSEKERSEWIRAIRQVCEDSNTPKSYRYHPGLWSGKKWSCCKGLSR 212
Fly 213 TTFGCRAAAHWREANNNPSNGSSPAQNSTRSISPNSSTTNSQFSLQHNSSGSLGGGVGGGLGGGG 277
Fly 278 SLGLGGGGGGGGSCTPTSLQPQSSLTTFKQSPTLLNGNGTLLDANMPGGIPTP-GTPNSKAKDNS 341
Fly 342 HFVKLVVALYPFKAIEGGDLSLEKNAEYEVIDDSQEHWWKVKDALGNVGYIPSNYVKPKALLGLE 406
Fly 407 RYEWYVGDMSRQRAESLLKQGDKEGCFVVRKSSTKGLYTLSLHTK---VPQSHVKHYHIKQNARC 468
Fly 469 EYYLSEKHCCETIPDLINYHRHNSGGLACRLK--SSPCDRPVPPTAGLSHDKWEIHPMELMLMEE 531
Fly 532 LGSGQFGVVRRGKWRGSIDTAVKMMKEGTMSEDDFIEEAKVMTKLQHPNLVQLYGVCSKHRPIYI 596
Fly 597 VTEYMKHGSLLNYLR--RHEKTLIGNMGLLLDMCIQVSKGMTYLERHNYIHRDLAARNCLVGSEN 659
Fly 660 VVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEVLNYTRFSSKSDVWAYGVLMWEIFTCGKMPY 724
Fly 725 GRLKNTEVVERVQRGIILEKPKSCAKEIYDVMKLCWSHGPEERPAFRVLMDQL 777 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Btk29A | NP_001097121.1 | PH_Btk | 44..222 | CDD:269944 | 50/201 (25%) |
| SH3_Tec_like | 346..399 | CDD:212702 | 23/52 (44%) | ||
| SH2_Tec_family | 403..505 | CDD:198188 | 53/106 (50%) | ||
| PTKc_Tec_like | 521..778 | CDD:173637 | 148/259 (57%) | ||
| Pkinase_Tyr | 526..777 | CDD:285015 | 146/252 (58%) | ||
| Btk | NP_038510.2 | PH_Btk | 6..166 | CDD:269944 | 49/197 (25%) |
| Inositol-(1,3,4,5)-tetrakisphosphate 1-binding. /evidence=ECO:0000250 | 12..24 | 6/11 (55%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 171..210 | 12/93 (13%) | |||
| SH3_BTK | 217..271 | CDD:212839 | 24/54 (44%) | ||
| SH2_Tec_Btk | 274..378 | CDD:198260 | 52/103 (50%) | ||
| PTKc_Btk_Bmx | 397..652 | CDD:173657 | 148/259 (57%) | ||
| Inhibitor-binding. /evidence=ECO:0000250 | 474..479 | 4/4 (100%) | |||
| CAV1-binding. /evidence=ECO:0000250 | 581..588 | 5/6 (83%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 316 | 1.000 | Domainoid score | I1270 |
| eggNOG | 1 | 0.900 | - | - | E2759_KOG0197 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 559 | 1.000 | Inparanoid score | I1093 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG52659 | |
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 1 | 1.000 | - | - | FOG0000006 | |
| OrthoInspector | 1 | 1.000 | - | - | otm44145 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_102306 | |
| Panther | 1 | 1.100 | - | - | O | PTHR24418 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 1 | 1.000 | - | - | X592 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| 11 | 10.830 | |||||