DRSC/TRiP Functional Genomics Resources

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Protein Alignment Btk and sla2a

DIOPT Version :10

Sequence 1:NP_476745.1 Gene:Btk / 34132 FlyBaseID:FBgn0003502 Length:786 Species:Drosophila melanogaster
Sequence 2:XP_009304328.1 Gene:sla2a / 100536664 ZFINID:ZDB-GENE-141216-296 Length:254 Species:Danio rerio


Alignment Length:229 Identity:58/229 - (25%)
Similarity:99/229 - (43%) Gaps:21/229 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly   348 VALYPFKAIEGGDLSLEKNAEYEVIDDSQEHWWKVKDALGNVGYIPSNYVKPKALLGLERYEWYV 412
            |||..|.:....:.::....:..:|.:..:.......:.||..:||..||..      ...:|:.
Zfish    34 VALCNFPSFRSDEHTICLGDKLNIISEDDDMLRVCSTSTGNECFIPHTYVSK------VHDQWFF 92

  Fly   413 GDMSRQRAESLLK-QGDKEGCFVVRKS-STKGLYTLSLHTKVPQSH-VKHYHIKQNARCEYYLSE 474
            ..:||:.||.||. ..:..|||::|:| |..|||:||:.....|.| |.||.|.|.....:|:..
Zfish    93 EGISRRNAEQLLMLPQNYSGCFLIRESQSFPGLYSLSVRQHSGQMHTVLHYKIYQLHNGWFYIQP 157

  Fly   475 KHCCETIPDLINYHRHNSGGLACRLKSSPC----------DRPVPPTAGLSHDKWEIHPMELMLM 529
            .|...|:..|::|:..:|.|..|.| :.||          ..|.|..|..|:..|......::..
Zfish   158 NHPFSTLSQLVDYYSRSSVGSFCHL-TEPCRLHDSIPTAAHSPSPVAAQKSNFNWRELSTSMIKR 221

  Fly   530 EELGSGQFGVVRRGKWRGSIDTAVKMMKEGTMSE 563
            :..|..|..:|..| .|.:::....:.:|.::.:
Zfish   222 QLKGMDQESLVSEG-LRETMNAYFYLAEESSLED 254

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
BtkNP_476745.1 PH_Btk 44..222 CDD:269944
SH3_Tec_like 346..399 CDD:212702 11/50 (22%)
SH2_Tec_family 403..505 CDD:198188 36/114 (32%)
PTKc_Tec_like 521..778 CDD:173637 6/43 (14%)
sla2aXP_009304328.1 SH3 32..86 CDD:473055 11/57 (19%)
SH2 79..180 CDD:472789 35/106 (33%)
Blue background indicates that the domain is not in the aligned region.

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