DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8086 and nup62l

DIOPT Version :9

Sequence 1:	NP_001260237.1	Gene:	CG8086 / 34131	FlyBaseID:	FBgn0032010	Length:	1603	Species:	Drosophila melanogaster
Sequence 2:	NP_001107068.1	Gene:	nup62l / 563392	ZFINID:	ZDB-GENE-030131-8491	Length:	507	Species:	Danio rerio

Alignment Length:	532	Identity:	106/532 - (19%)
Similarity:	158/532 - (29%)	Gaps:	167/532 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly  1107 TPAFTFGGKNDPKVE------------NNTPAPGDYHPEKVRQDHVPAFSFAGRHDLHKPNETPA 1159
            |..|.||   .||..            ::|||.|             .||| |.:.....|....
Zfish    10 TGGFNFG---TPKTTAAATTGFGVPQGSSTPAGG-------------GFSF-GANQPQTQNFGNP 57

  Fly  1160 PGAYSPEKVRQDHNPAFTMAGKHDPKVTHDTPAPGDYHPEKVRLDHNPAFSFAGRHDLHKPSETP 1224
            |...:....:...|...|..|......|..|.|.|             .|||.|  .|.|.|...
Zfish    58 PSQIAGLLAQPTQNNGSTQGGFSFGAQTQSTTAGG-------------GFSFGG--SLPKLSTPA 107

  Fly  1225 APGDYFPEKVRQDFNPA--------------FTFAGKHDPRSLSESPAPGDYSPEKVRLDHAPAF 1275
            ||            .||              |:..|.....:.::.|..|              |
Zfish   108 AP------------QPATTGVSLGASTTGTGFSLGGLTPQTTAAQQPMGG--------------F 146

  Fly  1276 SFGGKHDPKTEHLHPAPCDYAPEKVRLDHTPAYTIAGRPAADHVSQTPAPCDYHPEQCQVDSTPA 1340
            |||.   ||.:....||.         ..||..::..:|       |.......|....:.||.|
Zfish   147 SFGA---PKVQAASVAPA---------QPTPVLSLGVQP-------TTGLSLGAPTAASIASTTA 192

  Fly  1341 FTFGMRLGRERISDTPAPSAYEPEKHS------------LHSTPAYSFGTKSDIRVTTDAPAPGH 1393
            ..||:     :.|.||||::......|            :.|||...|...|...........|
Zfish   193 INFGI-----KTSATPAPASTALSSQSSTAPVSSLFANPIASTPVTGFTLGSSTASVAPVMTSG- 251

  Fly  1394 YHPEQCKLDSSPAYSFGLKTVPTASLPEPRGAYIEDRIVQRRERRLASPVRNNAECTTTTTNHTN 1458
                    .|:|| |..||  |..::|                     .:...|..|..||..:.
Zfish   252 --------SSAPA-SLSLK--PLGAVP---------------------AITTAAASTGATTGFSL 284

  Fly  1459 NNAGSSTTTTTTTTTTTKTFINGVEQPELQKKETTKQVNGTHKE--------LKSAPQAPLSNGN 1515
            ....:::|...:||.|:.|.:.....|.:...:....:|....|        |:.|.|....:..
Zfish   285 GLKTAASTALASTTATSTTVVTASTAPVMSYAQLEALINKWSSELEDQERHFLQQATQVNAWDRM 349

  Fly  1516 IVSNGNHSKMVSTTTRIQEVAHGQKE-SGNLKVVASGKSDASATKAAAVSHQTVVQADGAI-VTS 1578
            :|.||  .|:.:....:::|...|:. ...|..:.|.:.:..  ...:...::|.:..|.| :.:
Zfish   350 LVENG--EKITALHKDMEKVKLDQRRLDQELDFILSQQKELE--DLLSPLEESVKEQSGTIYMQN 410

  Fly  1579 GQSSRMQTVKYA 1590
            ....|.:|.|.|
Zfish   411 ADEERERTYKLA 422

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8086	NP_001260237.1	None
nup62l	NP_001107068.1	Nsp1_C	313..414	CDD:282867	16/104 (15%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R852
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.030