DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8086 and nsp1

DIOPT Version :9

Sequence 1:	NP_001260237.1	Gene:	CG8086 / 34131	FlyBaseID:	FBgn0032010	Length:	1603	Species:	Drosophila melanogaster
Sequence 2:	NP_594158.1	Gene:	nsp1 / 2542668	PomBaseID:	SPAC26A3.15c	Length:	598	Species:	Schizosaccharomyces pombe

Alignment Length:	510	Identity:	120/510 - (23%)
Similarity:	170/510 - (33%)	Gaps:	151/510 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   247 NKTPEFSFGIKHHEQRPDYTPAPGTYKPEQVVLEHIPAYSFGLKTKHIQVSDTPAPGAYSPEKSR 311
            |:...||||   ...:|: :.|.|...|....|       || .|.:...|..|:.|.:....:.
pombe     8 NQNSGFSFG---KPAQPN-SAAQGAATPAATGL-------FG-NTNNNTSSTAPSGGLFGSNNAS 60

  Fly   312 LHSAPAYSIAGKAS---QDVVDCTPAPGAY-----------EPEKCVLSRT-PAFSFGHRAELAK 361
            ..|||:....|||:   ......|.:|.::           :|....|..| .|.|.|.:::...
pombe    61 NTSAPSTFSFGKAATTGNSTNASTSSPFSFGSTNTNNTAGAKPLFGGLGSTGSANSTGDKSKNTA 125

  Fly   362 SSDT------PAPGTYN------------PEKVRLDHTPAF--------------TLSGRPETRS 394
            ||.|      |:..|:|            |.......|||.              |.|..|...|
pombe   126 SSATGAATTNPSGSTFNFGSSNNSFNFGKPASTTNTTTPAAASTGSLFGKPAATGTTSNAPPASS 190

  Fly   395 VSETPAPGSYAPEKYRNDRTPAFTFG-----GKHEQRLESSTPAPGDYCPEKVRHDHNPAFSFAG 454
            .|.|||.||           ..|:||     |.......|:|.              |..|||.
pombe   191 TSTTPATGS-----------GGFSFGKPASLGSTNNASTSTTA--------------NSGFSFG- 229

  Fly   455 RHDLHKPSDTPAPGAYDTEKVRQDHNPAFSFAGRHDLHKPSETPAPGAYSPEKVRQDHNPAFSMA 519
                 ||:.|.|||:..|.      .|:.|..|.:| .||:.:....|  |........||...|
pombe   230 -----KPATTSAPGSNTTV------TPSSSITGTND-SKPAASNTGSA--PTTGFSFGKPAGQAA 280

  Fly   520 GKHSQKVTSDSPAPGDYCPEKVRLDHTPAYSFGVKSDPKVENNTPAPGD--YHPEKVRQDHNPAY 582
            ...:.|.|:.:.:.|            ..:|||..:..:..|...||..  ..|.....|:.|.:
pombe   281 STATDKGTTTTSSAG------------TGFSFGKPATTEDTNKPTAPNSAFTKPATSTGDNKPTF 333

  Fly   583 SFAGRHDLQKP-DNTPAPGAYFPEKVRLDHNPAFSMAGKYDAKVTNDT-PAPG------DYSPEK 639
            ||.   :..|| :||.......|                   .::|:| ||.|      .:|..|
pombe   334 SFG---NTSKPTENTSTTATSAP-------------------PLSNNTKPAEGANQTSSGFSFGK 376

  Fly   640 VRQDTNPAYSFAGRHDLHKPSETPA-PGAYSPEKVRLDHNPAFTMAGKHDQKILN 693
            ...||..:.|..|....:||::..| |||.:  .......|..::..|..|:|||
pombe   377 PATDTTTSTSKTGPLFGNKPADPSAKPGATA--STTPSEPPPSSIKHKTLQEILN 429

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8086	NP_001260237.1	None
nsp1	NP_594158.1	Nsp1_C	407..520	CDD:282867	6/25 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R852
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940