Protein Alignment CG8086 and nup189

DIOPT Version :9

• Sequence 1: NP_001260237.1
• Gene: CG8086 / 34131
• FlyBaseID: FBgn0032010
• Length: 1603
• Species: Drosophila melanogaster
• Sequence 2: NP_594093.1
• Gene: nup189 / 2541547
• PomBaseID: SPAC1486.05
• Length: 1778
• Species: Schizosaccharomyces pombe
• Alignment Length: 1152
• Identity: 228/1152 - (19%)
• Similarity: 339/1152 - (29%)
• Gaps: 347/1152 - (30%)

  Fly   353 FGHRAELAKSSDTPAPGTYNPEKVRL----DHTPAFTLSGRPETRSVSETPAPGSYAPEKYRNDR 413
            ||..........|.|.|..|.:...|    .:||..||.|...|    .|...|....:......
pombe     2 FGQNNSSGFGGGTGAFGQNNQQTGGLFGSNSNTPGNTLFGSQNT----STTGFGQNTTQPLFGSN 62

  Fly   414 TPAFTFGGKHEQRL----------------ESSTPAPGDYCPEKVRHDHNPAFSFAGRHDLHKPS 462
            |....||.::....                :|:|||                  |.|.::...||
pombe    63 TNGGLFGNRNNTTTTGGTGFGMSSGTGMFGQSNTPA------------------FGGTNNATNPS 109

  Fly   463 DTPAPGAYDTEKVRQDHNPAFSF-----AGR---------HDLHKPSETPAPGAYSPEKVRQDHN 513
               ..|.:.:.....:.|...||     ||.         ..|...|.|||.            .
pombe   110 ---GGGLFGSNTANNNANTGTSFSFGSNAGSTGFGSQGTGGGLFGSSTTPAT------------T 159

  Fly   514 PAFSMAGKHSQKVTSDSPAPGDYCPEKVRLDHTPAYSFGVKSDPKVENNT--------PAPGDYH 570
            .||..:|    .|:|::.|        |.....|.|:...:.||:....:        ||...|.
pombe   160 NAFGTSG----FVSSNANA--------VNGTANPPYAVTSEKDPQTNGTSVFQSITCMPAYRSYS 212

  Fly   571 PEKVR-QDHNPAYSFAGRHDLQKPD---NTPAPGAY---FPEKVRLDHNPAFSMAGKYDAKVTND 628
            .|::| ||:|....|..........   :|||.||.   |.:.:....|.|....   .:..||.
pombe   213 FEELRLQDYNQGRRFGNASSTNTTSAFGSTPAFGASTTPFGQNLSGTTNNATPFG---TSNATNT 274

  Fly   629 TPAPGDYSPEKV--RQDTNPAYSFAGRHDL--------HKPSETPAPGAYSPEKVRLDHNPAFTM 683
            ||..|.:.....  ...||..:. :|.::.        :..:.||:.|.:...... ...|||:.
pombe   275 TPGSGLFGGGSAFGSNTTNTGFG-SGTNNASGGLFGQNNNTTSTPSTGLFGGSTFN-QQKPAFSG 337

  Fly   684 AGKHDQKILNGTPAP--GDYSPEKCRLDHTPAYSFGG--------------------KNDPKV-- 724
            .|........||...  |..:........|....|||                    .|.|..
pombe   338 FGSTTNTTNTGTGTGLFGSNNATNTGTGQTTGGLFGGAATGTGTGFGSSTGGFGSNTNNQPNSGT 402

  Fly   725 ---------ENNTPAPGDYHPEKVRLDHNPA-YSF-AGRHDLQKPS--------DTPAPGAYS-P 769
                     .||..|..:..|......:|.: :|| |..:...|||        .|||.|.:| .
pombe   403 MGTGLFGFGANNNTANNNTAPTSTFGGNNSSNFSFGANNNAATKPSGFGFGSTTTTPASGGFSFG 467

  Fly   770 EKVRQDHNPAFSM------------------AGKPVEKLTNGTPAPGDYSPEKVRLNHTPAYTFG 816
            :.......|||..                  ||......||.|...|....   ..|...:..||
pombe   468 QNANNAPKPAFGSTATTAPKPAGTGLFGGLGAGANTNTATNATGTGGSLFG---NANTAGSNMFG 529

  Fly   817 GKNDPKVENNTPAPGDYHPEKVRQ-----------DHNPAFSFAGRHDLHKPNDTPAPGAYCPEK 870
            ..|     ::||..|.:...:...           .:|...:..|....:||:.|.. |.:....
pombe   530 SAN-----SSTPGTGLFGSTQTNNATSNTGTGLFGSNNANTTNTGGSLFNKPSTTTG-GLFGNTT 588

  Fly   871 VRQDHNPAFSMAGKYTQKVANDTPAPGDYSPEKVRLDHTPAYTFGGKNDPKVESNTPAPGDYHPE 935
            .:|   |:.:.:|.:.....|:.....::.          ...|||....:.:....|..|.:|
pombe   589 AQQ---PSTTTSGLFGASNTNNQAQTSNFG----------TGLFGGSQAGQQQQPLQASIDQNP- 639

  Fly   936 KVRQDHNPAFSFAGRH----NLQKPSDTPAPGAYSPEKVR---------QDHNPA--FTMAGKHD 985
               ..:||.||.....    ::|:|..:|.....:|:|..         :.||.|  .:::....
pombe   640 ---YGNNPLFSSTTSQVAPTSIQEPIASPLTSKPTPKKAASLPQFWLSPRSHNTARLASISSFAK 701

  Fly   986 PKVSNDTPAPGDYSPEKVRL------DYTPSF-TFAGKNNPK-----------------VENDTP 1026
            ..|.|.|.|.|  .|:.:.|      |...|. .|..:.|.|                 |:|...
pombe   702 SAVMNSTSASG--KPKSLHLFDSLNDDVLLSADAFTPRQNIKKLVITHKISKDDILQNGVKNGND 764

  Fly  1027 APGDYHPEKVRQDHNPAFSFAG--RHDLH---------KPSDTPAPGAYSPEKVRQDHNPAFSMA 1080
            |..|   .|| |:..|.....|  :.|.|         ||| ......|..||:...|.  ||:.
pombe   765 AKSD---SKV-QEKAPQNEADGSLKKDEHVVLSDDYWMKPS-IEELSKYPKEKLCSVHQ--FSVG 822

  Fly  1081 -------------------------GKYI---EKITNGTPAPGDYCPEKVRLDHTPAFTFGGKND 1117
                                     ||.:   .||....|..|...|....| :.||.....|..
pombe   823 RTGYGQVAFLKPVDLSGFEKLEDIPGKVVVFERKICAVYPVEGSSPPLGEGL-NVPAIITLEKTW 886

  Fly  1118 P-KVENNTPAPGDYHP---EKVRQDH------------------VPAFSFAGRHDLHKPNETPAP 1160
            | ..|...|.....:|   :.|::.|                  |..||..|..|..:.....:.
pombe   887 PLSRETREPIKDPQNPRYIQHVKRLHRIKDTEFIDFNDGKWIFKVQHFSRYGLLDDEEEENDMSS 951

  Fly  1161 GAYSPEKVRQDHNPAFTMAGKHDPKVTHDTPA--PGDYHPEKVRLDHNPAFSFAGRHDLHKPSET 1223
            .:.....:::...|...::||:|..|||.||.  |.|...:::           .||.|......
pombe   952 TSNEAGNLKKYDQPNLKVSGKNDSFVTHHTPGAFPNDSKNKEL-----------NRHFLKVDDSA 1005

  Fly  1224 PAPGDYFPEKVRQDFNPAFTFAGKHDPRSLSESPAPGDYSPEKVRLD 1270
            |....:..:||:.||:         ...::||.   |||.....::|
pombe  1006 PLDDTFMSKKVKLDFS---------SDSNVSER---GDYDDNAKKVD 1040

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8086	NP_001260237.1	None
nup189	NP_594093.1	Nucleoporin_FG	19..132	CDD:290362	25/137 (18%)
		Nucleoporin_FG	241..337	CDD:290362	22/100 (22%)
		Nucleoporin_FG	515..601	CDD:290362	16/97 (16%)
		Nucleoporin2	795..934	CDD:282016	27/142 (19%)
		Nup96	1334..1629	CDD:288926

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R852
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030