DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pvr and Ceacam20

DIOPT Version :9

Sequence 1:	NP_001162911.1	Gene:	Pvr / 34127	FlyBaseID:	FBgn0032006	Length:	1577	Species:	Drosophila melanogaster
Sequence 2:	XP_006540423.1	Gene:	Ceacam20 / 71601	MGIID:	1918851	Length:	579	Species:	Mus musculus

Alignment Length:	427	Identity:	96/427 - (22%)
Similarity:	165/427 - (38%)	Gaps:	90/427 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   486 SENNFKILSTEL-----STMLQVLNAQLQDSGTYVLRGSNSFGVVQREYNVSVM-----DAPALK 540
            |.|:..:|:..:     :..|.:|..|.:|||:|:....:.| .|||....|:.     |..::|
Mouse    85 SNNSLLVLNERMKLSADNKTLTILIVQREDSGSYLCEVQHGF-EVQRSNTASLTVNYGPDPVSIK 148

  Fly   541 MSDAY-------VQVGSVARLECTVRSYP-PAIVTFFFRPCSLEPQWPTCSVLNQNFSLPSEQEK 597
            :....       |..|:........:|.| ||...:                      |||:
Mouse   149 LDSGVAAGDVVEVMEGNTVNFRVEAQSSPVPAYAWY----------------------LPSD--- 188

  Fly   598 YQFQTRPRPGKLSVERIYEVSFLPTEPGILTCIAQNIIDGKERRTLTKAHVLLGNISENMTIYGF 662
              |...|..|..:::.:..     ...|:..|:..|.:....|..:.|..||....:.|:.   |
Mouse   189 --FIQPPTTGTFTIDAVSR-----EHEGMYRCLVSNPVTNLSRLGVVKVQVLEKVTAPNIE---F 243

  Fly   663 DKDHKIAKEDNVNFTCEALAYHFDGNLKWFINGEDLKESDSVHIETSHTKYSYKSTVHITTISDR 727
            .....:....:|..||:  ..|....:.||:.|:.|:.||.:      |..|...|:.|..:...
Mouse   244 PTLALVENATSVTLTCK--TSHQRVGVHWFLKGQPLRPSDRL------TLSSQNRTLTIHGLQRD 300

  Fly   728 DRGTYECRAYHNDKDAVYSSREIDLYV---HDPSAPQWTNGGQEG-HSKIKRKLSQTLELECAST 788
            |.|.|||..::....|    |.:.|.:   :.|...:.|.|...| .|.|:..|:.:|.|.|.:.
Mouse   301 DIGPYECEVWNWGSQA----RSVPLKLTINYGPDQVEITQGPASGVVSTIEAMLNSSLTLYCRAD 361

  Fly   789 AVPVAIVRWFKDDKEVTESKLRHIIEKESKLLITHLYPGDEGVYKCVVENRLDRIERSFTVVI-- 851
            ::|.|..:|       |......:::.| :|.|..|....:|:|.|...|.:..:.||.:|::
Mouse   362 SIPGARYQW-------THEHSSKVLDGE-QLSIEALRQEHQGIYSCTSSNDVTGLARSASVLVMV 418

  Fly   852 --------SDLPGISMAWVWFGVILFLIL-IGLCVFL 879
                    |..|| ::|.:..|:::.:.| |||..||
Mouse   419 VGRGLQSSSMSPG-AIAGIVIGILVAIALAIGLGYFL 454

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pvr	NP_001162911.1	IG	346..432	CDD:214652
		Ig	<363..432	CDD:299845
		Ig	466..533	CDD:299845	14/51 (27%)
		IG_like	672..754	CDD:214653	22/81 (27%)
		Ig	674..739	CDD:143165	19/64 (30%)
		IGc2	779..840	CDD:197706	15/60 (25%)
		PKc_like	927..1332	CDD:304357
		Pkinase_Tyr	935..1329	CDD:285015
Ceacam20	XP_006540423.1	Ig	63..139	CDD:386229	15/54 (28%)
		Ig_3	160..217	CDD:372822	14/88 (16%)
		Ig	234..326	CDD:386229	24/106 (23%)
		IG_like	344..416	CDD:214653	21/79 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000