Sequence 1: | NP_001162911.1 | Gene: | Pvr / 34127 | FlyBaseID: | FBgn0032006 | Length: | 1577 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_066124.1 | Gene: | RET / 5979 | HGNCID: | 9967 | Length: | 1114 | Species: | Homo sapiens |
Alignment Length: | 1103 | Identity: | 261/1103 - (23%) |
---|---|---|---|
Similarity: | 432/1103 - (39%) | Gaps: | 339/1103 - (30%) |
- Green bases have known domain annotations that are detailed below.
Fly 434 KQNESYLNVGEPSGHYNV-QEYANRTIQMTANFEGFPTPSFSWFKPDGTEVRQSENNFKILSTEL 497
Fly 498 STMLQVLNAQ-LQDSGTYVLRGSNSF--GVVQREYNVSVMDAPALKMSDAYVQV-GSVARLECTV 558
Fly 559 RSYPPAIVTFFFRPCSLEPQWPTCSVLNQNFSLPSEQEKYQ---------FQTRPRPGKLSVERI 614
Fly 615 YEVSFLPTEPGILTCIAQNIIDGKERRTLTKAHVLLGNISENMTIYGFDKDHKIAKEDNVNFTCE 679
Fly 680 ALAYHFDG-NLKWFINGEDLKESDSVHIETSHTKYSYKSTVHITTISDRDRGTYECRAYHNDKDA 743
Fly 744 VYSSREIDLYVHDPSAPQWTNGGQEGHSKI--------------------KRKLSQTLELECAST 788
Fly 789 AVPVAIVRWFKDDK----------------------EVTESKLRHIIEKE---SKLLITH----- 823
Fly 824 -----------LYPGDEGVYKCVVENRLDRI--ERSFTVVISDLPGISMAWVWFGVILFLILIGL 875
Fly 876 CVFLAVRYQK-EHKRHLA------LKAAGLANFEEGAVGHINPDL-TLDEQAELLPY----NREF 928
Fly 929 EFPRENLKLGKQLGAGAFGVVLKGEAKGIRREEPTTTVAVKMVKATADNEVVRALVSELKIMVHL 993
Fly 994 GQHLNVVNLLGAVTKNIAKRELMVIVEYCRFGNIQNFLLRNRKCFINQINPDTDHIDPSIMTQRM 1058
Fly 1059 SDNYELHRDTNGGGLKYANVGFPIHSYINEPHNNNTQPPTHRRNSDNDPRSGTRAGRTGSGTATY 1123
Fly 1124 SYDRQMDTCATVMTTVPEDDQIMSNNSVQPAWRSNYKTDSTEAMTVTTVDLISWAFQVARGMDYL 1188
Fly 1189 SSKKVLHGDLAARNILLCEDNVVKICDFGLARSMYRGDNYKKSENGKLPIKWLALESLSDHVFST 1253
Fly 1254 YSDVWSYGIVLWEMFSLAKVPYPGIDPNQELFNKLNDGYRMEKPKFANQELYEIMLECWRKNPES 1318
Fly 1319 RPLFAELEKRFANMLGEDVASHYLDLNNPYMQSNIEY---MKKQSTDYLALMGSPDELAPAAPRY 1380
Fly 1381 VNGHIVPDIRIEELPDDYME-----MSRDSDPDACTAIFSP---TRLEGESSDFPDFSSETTF 1435 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
Pvr | NP_001162911.1 | IG | 346..432 | CDD:214652 | |
Ig | <363..432 | CDD:299845 | |||
Ig | 466..533 | CDD:299845 | 15/69 (22%) | ||
IG_like | 672..754 | CDD:214653 | 14/82 (17%) | ||
Ig | 674..739 | CDD:143165 | 10/65 (15%) | ||
IGc2 | 779..840 | CDD:197706 | 13/101 (13%) | ||
PKc_like | 927..1332 | CDD:304357 | 133/404 (33%) | ||
Pkinase_Tyr | 935..1329 | CDD:285015 | 128/393 (33%) | ||
RET | NP_066124.1 | Cadherin | 172..261 | CDD:278457 | 6/28 (21%) |
PTKc_RET | 723..1012 | CDD:173631 | 130/403 (32%) | ||
Pkinase_Tyr | 724..1005 | CDD:285015 | 128/393 (33%) | ||
Inhibitors binding | 805..807 | 1/1 (100%) | |||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_KOG0200 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
2 | 1.810 |