Protein Alignment Pvr and kitb

DIOPT Version :9

• Sequence 1: NP_001162911.1
• Gene: Pvr / 34127
• FlyBaseID: FBgn0032006
• Length: 1577
• Species: Drosophila melanogaster
• Sequence 2: NP_001137390.1
• Gene: kitb / 497629
• ZFINID: ZDB-GENE-050916-2
• Length: 957
• Species: Danio rerio
• Alignment Length: 1080
• Identity: 289/1080 - (26%)
• Similarity: 457/1080 - (42%)
• Gaps: 254/1080 - (23%)

  Fly   330 KPVIRSSVEHHV-FTDTNFTLDCEQSAYVESVYG-MEWFTPSRDENRIFASQSRTDPKTRNSTHQ 392
            ||||.....|.| .......|.|...|.|.:  | :.|.   ||:.|....:.:.|
Zfish    22 KPVITPDAPHLVILKGKQLYLRCHDDADVNA--GRVRWL---RDKGRRIEGELKDD--------- 72

  Fly   393 TGRSTLTVLN-AQPSDTGLYKCVTTDNSNQN-------------VQRATYRIKVLKQNESYLN-- 441
              .:::.:|| .:....|.|.|..|:...::             |:|....::|.|..|..|.
Zfish    73 --EASVILLNITETQHMGNYTCENTETEEKSSIYIYVKDLGSAFVRRMVNDLQVRKGEEITLPCL 135

  Fly   442 VGEPS-GHYNVQEYANRTIQMTANFEGFPTP-SFSWFKPDGTEVRQSENNFKILSTELSTMLQVL 504
            |.:|: .|.::|         |.|....|.. :|......|..:|.....|:
Zfish   136 VTDPAVSHLSLQ---------TCNGSALPAALTFITHPQGGITIRNVSKAFE------------- 178

  Fly   505 NAQLQDSGTYVLRGS-NSFGVVQREYNVSVMDAPALKMSDAYVQVGSVARLECTVRSYPPAIVTF 568
                   |.|...|. :...|..||||:.|..||      ..|...|::|.|..:     .|...
Zfish   179 -------GCYFCAGQLDQKPVKSREYNLVVRLAP------ESVPAISLSRNENVI-----LIQDQ 225

  Fly   569 FFRPCSLEPQWPTCSVLNQN------FSLPSEQEKYQ-FQTRPRPGKLSVER---IYEVSFLPTE 623
            .|:        .:||.:|.|      :::|||....: .::..:||....:|   ::..|....:
Zfish   226 EFK--------LSCSAVNINHDFHLRWTIPSEATALESHKSNIQPGSREYQRSITLWIQSVKIND 282

  Fly   624 PGILTCIAQNIIDGKERRTLTKAHVLLGNISENMTIY---------GFDKDHKIAKEDNVNFTCE 679
            .|...|.|:|      .:.::.|.|       |:.:|         |.::..::.:.:::..:.|
Zfish   283 TGSYRCNARN------EKGVSMAAV-------NLEVYERGFINLTEGENRVVEVREGESLTLSVE 334

  Fly   680 ALAYHFDGNLKWFINGEDLKESDSVHIETSHT-KYSYKSTVHITTISDRDRGTYECRAYHNDKDA 743
            ..:|....::.|..|.::| ::.|.|:.|.|. :|.|.|.:.:..:...:.|.|...|.|.
Zfish   335 ITSYPKPNDVLWTYNNQEL-QNTSEHVITLHNQQYRYISELRLVRVHGSEGGIYTFSANHK---- 394

  Fly   744 VYSSREIDLYVHDPSAPQWTNGGQEGHSKIKRKLSQTLELECASTAVPVAIVRWFKDDKEVTESK 808
             |.|......||....|...:  |||        ....::.|.::..||..:.|:.  .|...::
Zfish   395 -YESVNQSFTVHVICKPVIVS--QEG--------PVDGQVRCVASGYPVPKISWYY--CEPPHTR 446

  Fly   809 LRHII----------------------EKESKLLITHLYPGDEGVYKCVVENRLDRIERSFTVVI 851
            ..|::                      |.||:|.|:   .|.....:||...:.::....|::..
Zfish   447 CSHLLNATQADEEFAVITVSGSEFGRSEVESRLNIS---KGKFHTLECVASAQGEQAYTLFSISE 508

  Fly   852 SDLPGISMAWVWFGVILFLILIG-LCVFLAVRYQKEHKRHLALKAAGLANFEEGAVGHINPDLTL 915
            ..:|......:..||:...:|:. :.|.|..:|.::.|..:..|.  :.:|:.....:|:|
Zfish   509 RTVPHKLFTPLLSGVVSTSVLLSFILVVLLYKYMQKPKYEIHWKV--IDSFDGNNYTYIDP---- 567

  Fly   916 DEQAELLPYNREFEFPRENLKLGKQLGAGAFGVVLKGEAKGIRREEPTTTVAVKMVKATADNEVV 980
                ..|||:.::|||||.|:.||.||:||||.|:...|.|:...:..|||||||:|.:|.:...
Zfish   568 ----TQLPYDPKWEFPRERLRFGKILGSGAFGKVVAATAYGLCSADTVTTVAVKMLKPSAHSTEK 628

  Fly   981 RALVSELKIMVHLGQHLNVVNLLGAVTKNIAKRELMVIVEYCRFGNIQNFLLRNRKCFINQINPD 1045
            .||:||||::.::|.|:|:||||||.|   .....:||.|||.:|::.|||.|.|..|
Zfish   629 EALMSELKVLSYIGNHINIVNLLGACT---VGGPTLVITEYCCYGDLLNFLRRKRDAF------- 683

  Fly  1046 TDHIDPSIMTQRMSDNYELHRDTNGGGLKYANVGFPIHSYINEPHNNNTQPPTHRRNSDNDPRSG 1110
                    .:.:..|.|            |.|:            .:.|||..  ..:||    |
Zfish   684 --------FSSKTGDGY------------YKNL------------LSQTQPSI--EGTDN----G 710

  Fly  1111 TRAGRTGSGTATYSYDRQMDTCATVMTTVPEDDQIMSNNSVQPAWRSNYKTDSTEAMTVTTVDLI 1175
            ....|        ||.::                     |.|..|     .|..:.:::.|.||:
Zfish   711 YMPMR--------SYQKR---------------------SNQTEW-----CDDKDDLSLDTEDLL 741

  Fly  1176 SWAFQVARGMDYLSSKKVLHGDLAARNILLCEDNVVKICDFGLARSMYRGDNYKKSENGKLPIKW 1240
            |:::|||:|||:|:||..:|.||||||:||.:..|.|||||||||.:.|..||....|.:||:||
Zfish   742 SFSYQVAKGMDFLTSKNCIHRDLAARNVLLTQGRVAKICDFGLARDITRDSNYVLRGNARLPVKW 806

  Fly  1241 LALESLSDHVFSTYSDVWSYGIVLWEMFSLAKVPYPGIDPNQELFNKLNDGYRMEKPKFANQELY 1305
            ::.|||...|::..||||||||:|||:|||...|||||......:..:.|||||.:|:||..|:|
Zfish   807 MSPESLFACVYTFESDVWSYGILLWEIFSLGNTPYPGIPVGSTFYKMIQDGYRMSEPEFAPSEIY 871

  Fly  1306 EIMLECWRKNPESRPLFAELEKRFANMLGEDVASHYLDLN 1345
            |:|..||..:|..||.|.:|.:|...:|.|.....||:|:
Zfish   872 EVMRWCWSADPLKRPPFKKLVERTELLLSETTKHDYLNLS 911

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pvr	NP_001162911.1	IG	346..432	CDD:214652	18/100 (18%)
		Ig	<363..432	CDD:299845	13/82 (16%)
		Ig	466..533	CDD:299845	13/68 (19%)
		IG_like	672..754	CDD:214653	18/82 (22%)
		Ig	674..739	CDD:143165	15/65 (23%)
		IGc2	779..840	CDD:197706	14/82 (17%)
		PKc_like	927..1332	CDD:304357	154/404 (38%)
		Pkinase_Tyr	935..1329	CDD:285015	148/393 (38%)
kitb	NP_001137390.1	IG_like	121..201	CDD:214653	23/108 (21%)
		Ig	209..305	CDD:299845	23/121 (19%)
		IG	225..305	CDD:214652	19/100 (19%)
		Ig	309..407	CDD:299845	21/103 (20%)
		I-set	319..406	CDD:254352	19/92 (21%)
		PKc_like	547..896	CDD:304357	161/440 (37%)
		Pkinase_Tyr	583..894	CDD:285015	148/392 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	295	1.000	Domainoid score	I1456
eggNOG	1	0.900	-	-		E1_KOG0200
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D126783at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm25366
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.820