DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pvr and Cad96Ca

DIOPT Version :9

Sequence 1:	NP_001162911.1	Gene:	Pvr / 34127	FlyBaseID:	FBgn0032006	Length:	1577	Species:	Drosophila melanogaster
Sequence 2:	NP_651349.1	Gene:	Cad96Ca / 43026	FlyBaseID:	FBgn0022800	Length:	773	Species:	Drosophila melanogaster

Alignment Length:	450	Identity:	143/450 - (31%)
Similarity:	200/450 - (44%)	Gaps:	140/450 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   896 AGLANFEEGA-VGHINPDLTLDEQAELLPYNREFEFPRENLKLGKQLGAGAFGVVLKGEAKGIRR 959
            ||.:...|.| .|..|.|              .:||||..||....||.||||.|.:.||..|..
  Fly   444 AGSSGAPENAFAGEANCD--------------RWEFPRYRLKFFNILGEGAFGQVWRCEATNING 494

  Fly   960 EEPTTTVAVKMVKATADNEVVRALVSELKIMVHLGQHLNVVNLLGAVTKNIAKRELMVIVEYCRF 1024
            .|..||||||.:|.:|.....:.|:|||::|..|..|:|||:|||..|.   |....||:||...
  Fly   495 NEGITTVAVKTLKESATEVDRKDLLSELEVMKSLEPHINVVHLLGCCTD---KDPTFVILEYVNR 556

  Fly  1025 GNIQNFLLRNRKCFINQINPDTDHIDPSIMTQRMSDNYELHRDTNGGGLKYANVGFPIHSYINEP 1089
            |.:|.:|..:|.                                                   |.
  Fly   557 GKLQTYLRSSRA---------------------------------------------------ER 570

  Fly  1090 HNNNTQPPTHRRNSDNDPRSGTRAGRTGSGTATYSYDRQMDTCATVMTTVPEDDQIMSNNSVQPA 1154
            |..||.
  Fly   571 HYGNTH----------------------------------------------------------- 576

  Fly  1155 WRSNYKTDSTEAMTVTTVDLISWAFQVARGMDYLSSKKVLHGDLAARNILLCEDNVVKICDFGLA 1219
            .:||         .:|:.||.|:.:|||:|||||:|:.::|.||||||||:.:|:..|:.|||.|
  Fly   577 GKSN---------VLTSCDLTSFMYQVAKGMDYLTSRGIIHRDLAARNILITDDHTCKVADFGFA 632

  Fly  1220 RSMYRGDNYKKSENGKLPIKWLALESLSDHVFSTYSDVWSYGIVLWEMFSLAKVPYPGIDPNQEL 1284
            |.:.....|::...|||||:|:|.|||.|::||..||:||:||::||:.:|...|||||.. .::
  Fly   633 RDVITSKIYERKSEGKLPIRWMATESLYDNIFSVKSDIWSFGILMWEIVTLGSTPYPGISA-ADV 696

  Fly  1285 FNKLNDGYRMEKPKFANQELYEIMLECWRKNPESRPLFAELEKRFANMLGEDVASHYLDL 1344
            ..|:.||||:|||:...:|||.||..||..:|:.||||||:.:....:|..::  .|::|
  Fly   697 MRKVRDGYRLEKPEHCRRELYNIMYYCWSHDPQERPLFAEIIQMLDKLLHTEM--DYIEL 754

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pvr	NP_001162911.1	IG	346..432	CDD:214652
		Ig	<363..432	CDD:299845
		Ig	466..533	CDD:299845
		IG_like	672..754	CDD:214653
		Ig	674..739	CDD:143165
		IGc2	779..840	CDD:197706
		PKc_like	927..1332	CDD:304357	133/404 (33%)
		Pkinase_Tyr	935..1329	CDD:285015	129/393 (33%)
Cad96Ca	NP_651349.1	Cadherin_repeat	65..164	CDD:206637
		STYKc	470..741	CDD:214568	129/393 (33%)
		PTKc	474..742	CDD:270623	127/390 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45455289
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0200
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24416
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840