DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pvr and pdgfrl

DIOPT Version :9

Sequence 1:	NP_001162911.1	Gene:	Pvr / 34127	FlyBaseID:	FBgn0032006	Length:	1577	Species:	Drosophila melanogaster
Sequence 2:	NP_956608.2	Gene:	pdgfrl / 393284	ZFINID:	ZDB-GENE-040426-901	Length:	371	Species:	Danio rerio

Alignment Length:	188	Identity:	46/188 - (24%)
Similarity:	70/188 - (37%)	Gaps:	35/188 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   147 SSIYVYVNDPDTKLVDS---HNVVTARQYTDVVIPCKPAMPDTEVLL--ETSNGEMHSSKSVGRY 206
            |:.|:|..|.|...|.|   ..::..|......|||:...|..:|.|  |....|:....:...|
Zfish   155 SATYIYFTDKDELFVPSAIHFEIIYLRPDKPATIPCRVTNPKIKVSLHREVPAEEIAVDGTQISY 219

  Fly   207 DPQRGFTIEIRSIVDGGDYYCRPNPPFPHNEEEMTSIEVRFIATGLDIPRTQTTNMVYTYAPGVT 271
            :|.:||.|:..|....|.|||:.|.......:..|..::.::    ::|.......:...:..|:
Zfish   220 NPTKGFIIQNPSPEHKGAYYCKANSTSKTTPQISTKYQLLYV----EVPSGPPFATIEASSNSVS 280

  Fly   272 DGDDEVLTVTNQSTGNLALIRGGDGTLSRERARRSPARLAPMNASPSPR-PGQDGKPL 328
            .||  |..||....|.                       ..||.|.|.| ||||.:|:
Zfish   281 GGD--VFNVTCTVLGE-----------------------PEMNVSFSWRYPGQDQRPV 313

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pvr	NP_001162911.1	IG	346..432	CDD:214652
		Ig	<363..432	CDD:299845
		Ig	466..533	CDD:299845
		IG_like	672..754	CDD:214653
		Ig	674..739	CDD:143165
		IGc2	779..840	CDD:197706
		PKc_like	927..1332	CDD:304357
		Pkinase_Tyr	935..1329	CDD:285015
pdgfrl	NP_956608.2	IG_like	178..249	CDD:214653	20/70 (29%)
		Ig	186..249	CDD:143165	19/62 (31%)
		Ig	287..356	CDD:299845	13/50 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	49	1.000	Domainoid score	I11782
eggNOG	1	0.900	-	-		E1_KOG0200
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.900