Protein Alignment Pvr and Styk1

DIOPT Version :9

• Sequence 1: NP_001162911.1
• Gene: Pvr / 34127
• FlyBaseID: FBgn0032006
• Length: 1577
• Species: Drosophila melanogaster
• Sequence 2: NP_766479.1
• Gene: Styk1 / 243659
• MGIID: 2141396
• Length: 429
• Species: Mus musculus
• Alignment Length: 568
• Identity: 120/568 - (21%)
• Similarity: 217/568 - (38%)
• Gaps: 176/568 - (30%)

  Fly   827 GDEG-----VYKCVVENRLDRI-ERSFTVVISDLPGISMAWVWFGVILFLILIGLCVFLAVRYQK 885
            |::|     :.:|.:.::|..: |:.:.|:|  :|.:.:..       ||||:.:.::|.:|.|:
Mouse     2 GEKGHLSRVLLECSLSDKLCVVREKQYEVII--VPALLVGG-------FLILLAIILWLFIRGQR 57

  Fly   886 EHK-----RHLALKAAGLANFEEGAVGHINPDLTLDEQAELLPYNR---------------EFEF 930
            ..:     |..|...|.....:| |.||        .:..|||...               :.:.
Mouse    58 SQRQSPGPRGTASVPASRGRSQE-AAGH--------GEKVLLPLKETSVEGFLRAATPRLAKLQV 113

  Fly   931 PREN-LKLGKQLGAGAFGVVLKGEAKGIRREEP-TTTVAVKMVKATADNEVVRALVSELKIMVHL 993
            |||. |::.:|:.:|:.|.:.  .|....::.| ..:|.:|.::.....:.|:..:..::...:|
Mouse   114 PREQLLEVLEQIHSGSCGTLY--HATMTTKDHPKPKSVVLKALEDPVGLQEVQDFIGRIQFYQYL 176

  Fly   994 GQHLNVVNLLGAVTKNIAKRELMVIVEYCRFGNIQNFLLRNRKCFINQINPDTDHIDPSIMTQRM 1058
            |:|.|:|.|.|..|:.:   .|.:::|....|::.:||...|:               .:||.
Mouse   177 GKHKNLVQLEGCCTERL---PLYMMLEDVVPGDLLSFLWTCRR---------------DVMTM-- 221

  Fly  1059 SDNYELHRDTNGGGLKYANVGFPIHSYINEPHNNNTQPPTHRRNSDNDPRSGTRAGRTGSGTATY 1123
                        .||.|
Mouse   222 ------------DGLLY------------------------------------------------ 226

  Fly  1124 SYDRQMDTCATVMTTVPEDDQIMSNNSVQPAWRSNYKTDSTEAMTVTTVDLISWAFQVARGMDYL 1188
                                                  |.||.      .:.....|:...:::|
Mouse   227 --------------------------------------DLTEK------QIYHIGKQILLALEFL 247

  Fly  1189 SSKKVLHGDLAARNILLCEDNVVKICDFGLARSMYRGDNYKKSENGKLPIKWLALESLSDHVFST 1253
            ..|.:.|||:||||||:..|...|:|..|||..::.......:.:..:|:||||.|.|.....|.
Mouse   248 QEKHLFHGDVAARNILIQSDLTPKLCHLGLAYEVHAHGAISSARSSTIPLKWLAPERLLLRPASI 312

  Fly  1254 YSDVWSYGIVLWEMFSLAKVPYPGIDPNQELFNKLNDGYRMEKPKFANQELYEIMLECWRKNPES 1318
            ..|:||:||:|:||.:|...|||.:.|. .:...|.....|::|...:..:|.||..|||.:.:|
Mouse   313 RGDIWSFGILLYEMVTLGAPPYPEVPPT-SILQYLQRKKIMKRPSSCSHAMYNIMKCCWRWSEDS 376

  Fly  1319 RPLFAELEKRF--ANMLGEDVASHYL-DLNNPYMQSNIEYMKKQSTDY 1363
            |||..:|.:|.  |:...:|.|...: :|..|.:.:::..::.:|..|
Mouse   377 RPLLGQLLQRLEAASRSADDKAVLQVPELVVPELYADVAGIRAESISY 424

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pvr	NP_001162911.1	IG	346..432	CDD:214652
		Ig	<363..432	CDD:299845
		Ig	466..533	CDD:299845
		IG_like	672..754	CDD:214653
		Ig	674..739	CDD:143165
		IGc2	779..840	CDD:197706	3/17 (18%)
		PKc_like	927..1332	CDD:304357	89/408 (22%)
		Pkinase_Tyr	935..1329	CDD:285015	84/394 (21%)
Styk1	NP_766479.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	58..83		5/25 (20%)
		PKc_like	123..388	CDD:389743	84/391 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0200
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900