Sequence 1: | NP_001162911.1 | Gene: | Pvr / 34127 | FlyBaseID: | FBgn0032006 | Length: | 1577 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_004110.2 | Gene: | FLT3 / 2322 | HGNCID: | 3765 | Length: | 993 | Species: | Homo sapiens |
Alignment Length: | 1157 | Identity: | 278/1157 - (24%) |
---|---|---|---|
Similarity: | 441/1157 - (38%) | Gaps: | 310/1157 - (26%) |
- Green bases have known domain annotations that are detailed below.
Fly 319 PRPGQDGKPLPKPVIRSSVEHHVFTDTNF-TLDC--------EQSAYVESVYGMEWFTPSRDENR 374
Fly 375 IFASQSRTD------PKTRNSTHQ--------TGRSTLTVLNAQPSDTGLYKCV-TTDNSNQNVQ 424
Fly 425 -------RATYRIKVLKQNESYLNVGEPSGHYNV---QEYANRTIQMTANF-------------- 465
Fly 466 ------------EGFPTPSFSWFKPDGTEVRQSENNFKILSTELSTMLQVLNAQLQDSGTYVLRG 518
Fly 519 SNSFG-VVQREYNVSVMDAPALKMSDAYVQVGSVARLECTVRSYPPAIVTFFFRPCSLEPQWPTC 582
Fly 583 SV--LNQNFSLPSEQEKYQFQTRPRPGKLSVERIYEVSFLPTEPGILTCIAQNIIDGKERRTLTK 645
Fly 646 AHVLLGNISENMTIYGFDKDHKIAKEDNVNFTCEALAYHFDGNL-----KWFINGEDLKESDSV- 704
Fly 705 HIETSHTKYSYKSTVHITTISDRDRGTYECRAYHNDKDAVYSSREIDLYVHDPSAPQWTNGGQEG 769
Fly 770 HSK-------------IKRKLSQTL------ELECASTAVPVAIVRWFK-DDK------EVTESK 808
Fly 809 LRHIIEKE--------SKLLITHLYPGDEGVYKCVVENRLDRIERSFTVVISDLPG--------I 857
Fly 858 SMAWVWFGVILFLILIGLCVFLAVRYQKEHKRHLALKAAGLANFEEGAVGHINPDLTLDEQAELL 922
Fly 923 PYNREFEFPRENLKLGKQLGAGAFGVVLKGEAKGIRREEPTTTVAVKMVKATADNEVVRALVSEL 987
Fly 988 KIMVHLGQHLNVVNLLGAVTKNIAKRELMVIVEYCRFGNIQNFLLRNRKCFINQINPDTDHIDPS 1052
Fly 1053 IMTQRMSDNYELHRDTNGGGLKYANVGFPIHSYINEP----HNNNTQPPTH--RRNSDNDPRSGT 1111
Fly 1112 RAGRTGSGTATYSYDRQMDTCATVMTTVPEDDQIMSNNSVQPAWRSNYKTDSTEAMTVTTV-DLI 1175
Fly 1176 SWAFQVARGMDYLSSKKVLHGDLAARNILLCEDNVVKICDFGLARSMYRGDNYKKSENGKLPIKW 1240
Fly 1241 LALESLSDHVFSTYSDVWSYGIVLWEMFSLAKVPYPGIDPNQELFNKLNDGYRMEKPKFANQELY 1305
Fly 1306 EIMLECWRKNPESRPLFAELEKRFANMLGEDVASHYLDLNN-----PYMQSN 1352 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
Pvr | NP_001162911.1 | IG | 346..432 | CDD:214652 | 20/116 (17%) |
Ig | <363..432 | CDD:299845 | 16/90 (18%) | ||
Ig | 466..533 | CDD:299845 | 10/67 (15%) | ||
IG_like | 672..754 | CDD:214653 | 17/87 (20%) | ||
Ig | 674..739 | CDD:143165 | 13/70 (19%) | ||
IGc2 | 779..840 | CDD:197706 | 18/81 (22%) | ||
PKc_like | 927..1332 | CDD:304357 | 146/411 (36%) | ||
Pkinase_Tyr | 935..1329 | CDD:285015 | 140/400 (35%) | ||
FLT3 | NP_004110.2 | ig | 256..345 | CDD:278476 | 24/154 (16%) |
PKc_like | 572..947 | CDD:304357 | 150/450 (33%) | ||
Important for normal regulation of the kinase activity and for maintaining the kinase in an inactive state in the absence of bound ligand | 591..597 | 1/7 (14%) | |||
Pkinase_Tyr | 610..943 | CDD:285015 | 140/400 (35%) |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_KOG0200 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 1 | 1.010 | - | - | D126783at33208 | |
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 1 | 1.000 | - | - | otm41363 | |
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
4 | 3.820 |