DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pvr and R09D1.13

DIOPT Version :9

Sequence 1:	NP_001162911.1	Gene:	Pvr / 34127	FlyBaseID:	FBgn0032006	Length:	1577	Species:	Drosophila melanogaster
Sequence 2:	NP_496022.1	Gene:	R09D1.13 / 187740	WormBaseID:	WBGene00011169	Length:	388	Species:	Caenorhabditis elegans

Alignment Length:	495	Identity:	116/495 - (23%)
Similarity:	199/495 - (40%)	Gaps:	163/495 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   871 ILIGLCVFLAV-------RYQKEHKRHLALKAAGLANFEEGAVGHINPDLTLDEQAELLPYNRE- 927
            ::|.:|:|:||       ..||.:|:    |.........|..|.|.      ||.||.|.|::
Worm     5 LVILICIFIAVILFAFACILQKVYKK----KTQDRPALRRGKRGSIT------EQIELTPINKDD 59

  Fly   928 -------------FEFPRENLKLGKQLGAGAFGVVLKGEAK-GIRREEPTTTVAVKMVKATADNE 978
                         .|....|||....|..|.|..:.:|... .:..||..:...|.::.....|.
Worm    60 MCIRDNISIGNIPVEIDPSNLKFSSVLENGYFCKIRRGTLNINVTAEEKNSNKLVDVLVKRPKNH 124

  Fly   979 VVRALV-SELKIMVHLGQHLNVVNLLGAVTKNIAKRELMVIVEYCRFGNIQNFLLRNRKCFINQI 1042
            :.:.:: :||.|:..:|:|.||:.|:|..:....:  .:|:.|....||:|:.|
Worm   125 IEKEMLENELTILRLIGRHPNVLALIGYTSPMFGR--TVVVYESVELGNLQHVL----------- 176

  Fly  1043 NPDTDHIDPSIMTQRMSDNYELHRDTNGGGLKYANVGFPIHSYINEPHNNNTQPPTHRRNSDNDP 1107
                         :...:|:||             ||.|...:
Worm   177 -------------KITKNNFEL-------------VGVPETEF---------------------- 193

  Fly  1108 RSGTRAGRTGSGTATYSYDRQMDTCATVMTTVPEDDQIMSNNSVQPAWRSNYKTDSTEAMTVTTV 1172
                      ||...:        |.:
Worm   194 ----------SGLDEF--------CVS-------------------------------------- 202

  Fly  1173 DLISWAFQVARGMDYLSSKKVLHGDLAARNILLCEDNVVKICDFGLARSMYRGDNYK--KSENGK 1235
            ||.|:|||:|.||:||:...|:|..||.|||.|..:..::|.:|||::::   ::|:  .|.:..
Worm   203 DLHSFAFQIANGMEYLTHIPVIHRFLALRNIFLKRNKTIRIANFGLSKNV---NDYRIIDSMDTP 264

  Fly  1236 LPIKWLALESLSDHVFSTYSDVWSYGIVLWEMFSLAKVPYPGIDPNQELFNKLND----GYRMEK 1296
            :|:.|:|.||.::.:|:..:||||:|:.|:|::||.:.||..:   :.||:.|.:    |.|:.|
Worm   265 VPLYWMAPESYNELIFNEKTDVWSFGVCLYELYSLGEDPYENV---KTLFDHLMEYLEKGNRLSK 326

  Fly  1297 PKFANQ-ELYEIMLECWRKNPESRPLFAELEKRFANMLGE 1335
            ||:.:. |:::.|..||...||:||.|::..:.|.:.|.|
Worm   327 PKYIDSPEIFDFMKICWNFKPETRPCFSDCAQFFKSHLQE 366

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pvr	NP_001162911.1	IG	346..432	CDD:214652
		Ig	<363..432	CDD:299845
		Ig	466..533	CDD:299845
		IG_like	672..754	CDD:214653
		Ig	674..739	CDD:143165
		IGc2	779..840	CDD:197706
		PKc_like	927..1332	CDD:304357	96/427 (22%)
		Pkinase_Tyr	935..1329	CDD:285015	93/402 (23%)
R09D1.13	NP_496022.1	STYKc	80..360	CDD:214568	93/402 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0200
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D126783at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820