Protein Alignment Pvr and Fgfrl1

DIOPT Version :9

• Sequence 1: NP_001162911.1
• Gene: Pvr / 34127
• FlyBaseID: FBgn0032006
• Length: 1577
• Species: Drosophila melanogaster
• Sequence 2: NP_473412.1
• Gene: Fgfrl1 / 116701
• MGIID: 2150920
• Length: 529
• Species: Mus musculus
• Alignment Length: 473
• Identity: 97/473 - (20%)
• Similarity: 153/473 - (32%)
• Gaps: 171/473 - (36%)

  Fly   457 RTIQMTANFEGFPTPSFSWFKPDGTEVRQSENNFKILSTELSTMLQVLNAQLQDSGTYVLRGSNS 521
            ||:::....||.|.|...|.| ||..:....:.|::|...    |:|...:.:|:|.||.:.:|.
Mouse    41 RTVRLQCPVEGDPPPLTMWTK-DGRTIHSGWSRFRVLPQG----LKVKEVEAEDAGVYVCKATNG 100

  Fly   522 FGVVQREYNVSVMD--APALKMSDAYVQVGSVARLECTVRSYPPAIVTFFFRPCSLEPQWPTCSV 584
            ||.:...|.:.:||  :|.   .::....||....|      .||           ..||
Mouse   101 FGSLSVNYTLIIMDDISPG---KESPGPGGSSGGQE------DPA-----------SQQW----- 140

  Fly   585 LNQNFSLPSEQEKYQFQTRPRPGKLSVERIYEVSFLPTEPGILTCIAQNIIDGKERRTLTKAHVL 649
            ....|:.||:..:   :...||...||.              |.|:|..
Mouse   141 ARPRFTQPSKMRR---RVIARPVGSSVR--------------LKCVASG---------------- 172

  Fly   650 LGNISENMTIYGFDKDHKIAKEDNVNFTCEALAYHFDGNLKWFINGEDLKESDSVHIETS-HTKY 713
                                              |...::.|..:.:.|     .|:|.| |.|
Mouse   173 ----------------------------------HPRPDIMWMKDDQTL-----THLEASEHRK- 197

  Fly   714 SYKSTVHITTISDRDRGTYECRAYHNDKDAVYSSREIDLYVHDPSAPQWTN----------GGQE 768
             .|.|:.:..:...|.|.|.||. .|...|:.::.::|:.....|.|..|.          ||
Mouse   198 -KKWTLSLKNLKPEDSGKYTCRV-SNKAGAINATYKVDVIQRTRSKPVLTGTHPVNTTVDFGG-- 258

  Fly   769 GHSKIKRKLSQTLELECASTAVPVAIVRWFKDDKEVTESKLRHIIEKE----------------- 816
                       |...:|...:....:::|.|..:..:|.:....|:..
Mouse   259 -----------TTSFQCKVRSDVKPVIQWLKRVEYGSEGRHNSTIDVGGQKFVVLPTGDVWSRPD 312

  Fly   817 ----SKLLITHLYPGDEGVYKCVVENRLDRIERS-FTVVISD--LPGISMA---------W-VWF 864
                :||||:.....|.|:|.|:..|.:....|| |..|:.|  .||..||         | |..
Mouse   313 GSYLNKLLISRARQDDAGMYICLGANTMGYSFRSAFLTVLPDPKPPGPPMASSSSSTSLPWPVVI 377

  Fly   865 GV------ILFLILIGLC 876
            |:      ||..:|:.||
Mouse   378 GIPAGAVFILGTVLLWLC 395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pvr	NP_001162911.1	IG	346..432	CDD:214652
		Ig	<363..432	CDD:299845
		Ig	466..533	CDD:299845	20/66 (30%)
		IG_like	672..754	CDD:214653	18/82 (22%)
		Ig	674..739	CDD:143165	15/65 (23%)
		IGc2	779..840	CDD:197706	15/81 (19%)
		PKc_like	927..1332	CDD:304357
		Pkinase_Tyr	935..1329	CDD:285015
Fgfrl1	NP_473412.1	I-set	29..112	CDD:369462	22/75 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	116..151		11/59 (19%)
		Ig2_FGFRL1-like	153..234	CDD:143264	24/155 (15%)
		Ig	257..351	CDD:386229	20/106 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	405..427

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0200
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900