DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pvr and si:zfos-1069f5.1

DIOPT Version :9

Sequence 1:	NP_001162911.1	Gene:	Pvr / 34127	FlyBaseID:	FBgn0032006	Length:	1577	Species:	Drosophila melanogaster
Sequence 2:	XP_009305955.1	Gene:	si:zfos-1069f5.1 / 103912059	ZFINID:	ZDB-GENE-141215-70	Length:	449	Species:	Danio rerio

Alignment Length:	469	Identity:	102/469 - (21%)
Similarity:	167/469 - (35%)	Gaps:	143/469 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 IILDAQTSTTLKCEDDEPMSWWTSQSQYVHVKSFDNTEDPARPFGTSLHLIE-VTADYVAAYYCV 119
            :|||:.:...|.||.|.|:::....::  |.:.........|.|     |:| .|.|:...|.||
Zfish    36 VILDSGSPLQLVCEGDGPVTFLPRLAK--HKRYISKEVGKIRSF-----LVEKATVDFTGTYKCV 93

  Fly   120 KTSKFSQIAKEEQSDEAMIELVNQGYASSIYVYVND-------PDTKLVDSHNVVTARQYTDVVI 177
            ..:         .:|..:        :||::|:|.|       |.|.|     ....::..|:::
Zfish    94 YMN---------GNDSNL--------SSSVHVFVRDSRVLFVSPSTSL-----RYVRKEGEDLLL 136

  Fly   178 PCKPAMPDTEVLLETSNGEMHSSKSVG---RYDPQRGFTIEIRSIVDG--GDYYCRPN------- 230
            ||  .:.|.|....|...:..|:...|   .|||::|  :.||....|  |:|.|...
Zfish   137 PC--LLTDPEATNFTFRMDNVSAAPYGMNITYDPRKG--VLIRKAHPGFNGEYICSARIRGIEKV 197

  Fly   231 --------------PPFPH---NEEEMTSIEVRFIATGLDIPRTQTT-----NMVYTYAPGVTDG 273
                          ||:.:   ||      .|:.:...|.|..|...     |:.:|::..:...
Zfish   198 SKIFSINIIQRLRFPPYVYLKRNE------YVKLVGERLQISCTTNNPNFYYNVTWTHSSRMLPK 256

  Fly   274 DDE-------------VLTV--TNQS-TGNLALI----RGGDGTLSRERARRSP-ARLAPMNASP 317
            .:|             :||:  ..|| |||:...    .|.:.:.::......| .||:|..:|.
Zfish   257 AEEKSTMEVDHLAIESILTIPSVQQSHTGNITCTGQNEAGANSSTTQLLVVEEPYIRLSPKLSSK 321

  Fly   318 SPRPGQDGKPLPKPVIRSSVEHHVFTDTNFTLDCEQSAYVESVYGMEWFTP-----SRDENRIFA 377
            ....|            .|:|.....|.:..:..|  || ..:...:|.||     |..|||.|.
Zfish   322 LTHRG------------LSIEVSEGDDVDLGVLIE--AY-PPLTSHKWETPTSHNASLPENRFFN 371

  Fly   378 SQSRTDP----KTRNSTHQTGRSTLTVLNAQPS-----DTGLYKCVTTDNSNQNVQRATYRIKVL 433
            ...|.:.    |:.| ..:.|:.||.|.|:..:     |..:||     :::...|..|
Zfish   372 HNDRYEALLFLKSLN-FEEIGQYTLNVKNSMKNASITFDIKMYK-----STSVKAQWTT------ 424

  Fly   434 KQNESYLNVGEPSG 447
            .|:|...|..|..|
Zfish   425 GQSEDKTNCDETRG 438

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pvr	NP_001162911.1	IG	346..432	CDD:214652	24/99 (24%)
		Ig	<363..432	CDD:299845	21/82 (26%)
		Ig	466..533	CDD:299845
		IG_like	672..754	CDD:214653
		Ig	674..739	CDD:143165
		IGc2	779..840	CDD:197706
		PKc_like	927..1332	CDD:304357
		Pkinase_Tyr	935..1329	CDD:285015
si:zfos-1069f5.1	XP_009305955.1	Ig_2	31..110	CDD:316418	22/97 (23%)
		IG_like	126..200	CDD:214653	18/77 (23%)
		IG_like	222..306	CDD:214653	15/83 (18%)
		Ig	311..410	CDD:325142	27/114 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	49	1.000	Domainoid score	I11782
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D126783at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010