DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Snx6 and SNX2a

DIOPT Version :9

Sequence 1:	NP_001245939.1	Gene:	Snx6 / 34126	FlyBaseID:	FBgn0032005	Length:	455	Species:	Drosophila melanogaster
Sequence 2:	NP_200652.2	Gene:	SNX2a / 835957	AraportID:	AT5G58440	Length:	587	Species:	Arabidopsis thaliana

Alignment Length:	610	Identity:	134/610 - (21%)
Similarity:	226/610 - (37%)	Gaps:	196/610 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 DGTDDSNL-------------------------LNSPSTNNG---ATMEIASPTNPLATPPATGG 39
            ||.:::||                         :|..::|:|   |...:::..:|| :||.|..
plant     8 DGFEETNLNAQRDDMENLDLGVDGGDHPLKISDVNGDTSNSGYRSAMSTLSNVRDPL-SPPPTVM 71

  Fly    40 APAPSG-----------ATNGSGSATSPDSSSSAPATPA--------------VLG--ENALHVE 77
            .||.|.           .::.|....|.|:|...|.:.|              :.|  :|:||.:
plant    72 IPADSDPLLAPSSYEDFRSSFSSKPISSDNSYIEPPSYADVIFSPFDENSDSEINGTEDNSLHSQ 136

  Fly    78 ISDALS------------------EKEK------------VKFTVHTRTTLPGF-SKKDNNVVRQ 111
            .||:||                  :||:            :.:.:.|||.||.| ...:.:|.|:
plant   137 FSDSLSRSPSSSSSDYIKITVSNPQKEQEISNSIVGGNTYITYQITTRTNLPDFGGPSEFSVRRR 201

  Fly   112 HEEFVWLHDRIEENDDYAGYIIPPCPPRPDFDASREKLQRLGEGEGNMTKEEFKKMKSELEAEYL 176
            ..:.|.|.||:.|.  |.|:.|   |||||......::         |.|:||.:
plant   202 FRDVVTLADRLAET--YRGFCI---PPRPDKSVVESQV---------MQKQEFVE---------- 242

  Fly   177 ATFKKTVAMHEVFLRRLASHPVFRVDQHLKVFLEYDQDL---------------CAKPRKKMAIF 226
               ::.||: |.:||||::|||.|....|||||:....|               ..|..|::...
plant   243 ---QRRVAL-EKYLRRLSAHPVIRNSDELKVFLQVQGKLPLPMSTDVASRMLDGAVKLPKQLFGE 303

  Fly   227 GGF----VKSLGKTT----DEILLSATVRD--VNDF-------FENELQFLT------EYHGHLR 268
            ||.    |..:|:..    |.:.|...:|.  .||:       .|.:.:||.      :....:.
plant   304 GGASAVPVTEVGQPARGGRDLLRLFKELRQSVSNDWGGSKPPVVEEDKEFLEKKEKMHDLEQQII 368

  Fly   269 EAALRTEKMTQRHKDVGDSHQKISNALTQLSTTEKGNVETFVAKTAEIFERIKNLET-------- 325
            .|:.:.|.:.:..:|:|::..::..|..:|:..|  |.|............:|||.|
plant   369 NASQQAESLVKAQQDMGETMGELGLAFIKLTKFE--NEEAVCNPQRTRANDMKNLATAAVKASRF 431

  Fly   326 -RVASDQDLKLGDTLRYY--------QRDSDAAKALLIRR--LRCLAAYEAANRNLEKARSK--- 376
             |..:.|.:|..|||..|        ...:|.:.|||..:  |..|.:.:.....||.|.||
plant   432 YRELNSQTVKHLDTLHEYLGMMMAVQGAFADRSSALLTVQTLLSELPSLQTRVEKLEAASSKVFG 496

  Fly   377 -NKDVHAPLE-----VQEAETAQAEACEKFESMSACGKEELIGFRNRRVAAFKKSLVELSELEIK 435
             :|.....:|     ::..|.|:..|.:.:|.:....:.|:......|.|.|...:......::.
plant   497 GDKSRIRKIEELKETIKVTEDAKNVAIKGYERIKENNRSEVERLDRERRADFMNMMKGFVVNQVG 561

  Fly   436 HAK-------------TQYEYLRQS 447
            :|:             :||:..:||
plant   562 YAEKMGNVWAKVAEETSQYDREKQS 586

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Snx6	NP_001245939.1	PX_SNX5_like	72..212	CDD:132802	50/170 (29%)
Snx6	NP_001245939.1	BAR_SNX5_6	228..452	CDD:153305	57/284 (20%)
SNX2a	NP_200652.2	PX_SNX_like	154..274	CDD:132775	43/147 (29%)
SNX2a	NP_200652.2	BAR_SNX	348..576	CDD:153280	45/229 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910