DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Snx6 and Snx11

DIOPT Version :9

Sequence 1:	NP_001245939.1	Gene:	Snx6 / 34126	FlyBaseID:	FBgn0032005	Length:	455	Species:	Drosophila melanogaster
Sequence 2:	NP_001156861.1	Gene:	Snx11 / 74479	MGIID:	1921729	Length:	271	Species:	Mus musculus

Alignment Length:	169	Identity:	36/169 - (21%)
Similarity:	61/169 - (36%)	Gaps:	49/169 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 ENALHVEISDALSEKE-----KVKFTVHTRTTLPGFSKKDNNVVRQHEEFVWLHDRIEENDDYAG 130
            |..:.|.:.|...:.|     .|.:.:...|....|:.|.:.|.|::.|||||..:::.|   ||
Mouse    14 EEVITVRVQDPRVQNEGSWNSYVDYKIFLHTNSKAFTAKTSCVRRRYREFVWLRKQLQRN---AG 75

  Fly   131 YIIPPCPPRPD----FDASREKLQRLGEGEGNMTKEEFKKMKSELEAEYLATFKKTVAMHEVFLR 191
            .:  |.|..|.    |..|.|.:::..:|                            ..|  ||.
Mouse    76 LV--PVPELPGKSTFFGGSDEFIEKRRQG----------------------------LQH--FLE 108

  Fly   192 RLASHPVFRVDQHLKVFLEY-----DQDLCAKPRKKMAI 225
            ::....|...|..|.:||:.     :.:.|.:.|..|.:
Mouse   109 KVLQSVVLLSDSQLHLFLQSQLSVPEIEACVQGRGAMTV 147

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Snx6	NP_001245939.1	PX_SNX5_like	72..212	CDD:132802	32/153 (21%)
Snx6	NP_001245939.1	BAR_SNX5_6	228..452	CDD:153305
Snx11	NP_001156861.1	PX_SNX10	18..129	CDD:132808	32/145 (22%)
		Important for membrane trafficking. /evidence=ECO:0000250	135..139		0/3 (0%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	185..271
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845770
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930