DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Snx6 and Snx16

DIOPT Version :9

Sequence 1:	NP_001245939.1	Gene:	Snx6 / 34126	FlyBaseID:	FBgn0032005	Length:	455	Species:	Drosophila melanogaster
Sequence 2:	NP_071625.2	Gene:	Snx16 / 64088	RGDID:	620295	Length:	344	Species:	Rattus norvegicus

Alignment Length:	279	Identity:	59/279 - (21%)
Similarity:	107/279 - (38%)	Gaps:	85/279 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 DDSNLLNSPSTNNGATMEIASPT--NPLATPPATG-GAPAPSGATNGSGSATSPDSSS--SAPAT 65
            :||::.....||....|:.||..  :||.....|| .:.....|.........||:.:  ..|:|
  Rat    45 EDSSVGTCKHTNVQDQMDSASSVCGSPLIRTKFTGTDSSIEYSARPRDTEEQHPDALNWEDRPST 109

  Fly    66 PAVLGENALHVEISDALSEKEKVKFTVHTRTTLPGFSKKDNNVV-RQHEEFVWLHDRIEE----- 124
            |.:||...:          :|:.||||:  ..|...|.:::.|| |::.:|..|:|:::|
  Rat   110 PTILGYEVM----------EERAKFTVY--KILVKESPEESWVVFRRYTDFSRLNDKLKEMFPGF 162

  Fly   125 ----------NDDY-AGYI-------------------IPPC-----------PPRPDFDA---S 145
                      .|:| |.::                   |..|           ||.| ||:   |
  Rat   163 RLALPPKRWFKDNYNADFLEDRQLGLQAFLQNLVAHKDIANCLAVREFLCLDDPPGP-FDSLEES 226

  Fly   146 REKLQRLGEGEGNMTKEEFKKMK-----------SELEAEYLATFKKTVAMH---EVFLRRLASH 196
            |...:.|.|...::.:|..:|.|           .:|..:.|.|..:|:::.   .:::.|....
  Rat   227 RAFCETLEETNYHLQRELLEKQKEVESLKKLLGEKQLHIDALETRIRTLSLEPGASLYVSRAEGG 291

  Fly   197 PVFRVDQHLKVFLEYDQDL 215
            .:.||...:   |:.::|:
  Rat   292 QILRVQSSV---LQVNRDV 307

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Snx6	NP_001245939.1	PX_SNX5_like	72..212	CDD:132802	39/203 (19%)
Snx6	NP_001245939.1	BAR_SNX5_6	228..452	CDD:153305
Snx16	NP_071625.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..49		2/3 (67%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	83..105		3/21 (14%)
		PX_SNX16	105..214	CDD:132809	24/120 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910